Results 111 to 120 of about 7,921 (224)

Central composite design optimized fluorescent method using dual doped graphene quantum dots for lacosamide determination in biological samples

Scientific Reports
Lacosamide is a third-generation antiepileptic drug used for the treatment of partial-onset seizures. This study investigates the development and validation of a novel analytical method for the determination of lacosamide in human plasma and ...
Ahmed Serag, Rami M. Alzhrani, Reem M. Alnemari, Maram H. Abduljabbar, Atiah H. Almalki   +4 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Emotional Improvement Despite General Clinical Deterioration During Multidisciplinary Rehabilitation in Stiff Person Syndrome: A Longitudinal Case Report

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT We report a woman with anti‐GAD‐positive Stiff Person Syndrome undergoing two multidisciplinary neurorehabilitation admissions. A Transactional Analysis‐informed neuropsychotherapeutic intervention supported emotional adaptation and goal transition from recovery to adaptation.
Marianna Contrada, Federica Scarfone, Martina Vatrano, Isabel Mantia, Natascia De Cicco, Maria Girolama Raso, Antonio Cerasa, Maria Elena Pugliese, Valentina Errigo, Riccardo Spanò   +9 more
wiley   +1 more source

Comparative study evaluating the efficacy of duloxetine, gabapentin, and lacosamide on oxaliplatin-induced peripheral neuropathy

PAIN Reports
Introduction:. Peripheral neuropathic pain limits oxaliplatin use and negatively impacts patients' quality of life. Objectives:. This study was conducted to assess the impact of gabapentin and lacosamide on oxaliplatin-induced peripheral neuropathy ...
Sally Said Tantawy, Osama Mohamed Ibrahim, Sahar Mohamed El-Haggar, Mohamed Abouelfetouh Shehata   +3 more
doaj   +1 more source

Severe maternal morbidity in pregnancies complicated by maternal seizure disorder

Pregnancy, Volume 2, Issue 6, November 2026.
Abstract Introduction Seizure disorders are a common comorbidity of pregnancy, leading to increased maternal and neonatal complications. In particular, we sought to identify the impact of seizure disorders on severe maternal morbidity (SMM) and hypertensive disorders of pregnancy in a contemporary cohort.
Janki Amin, Brianna Lau, Brandie D. Taylor, Calla Holmgren, Rachel K. Harrison   +4 more
wiley   +1 more source

The retention of lacosamide in patients with epilepsy and intellectual disability in three specialised institutions

, 2017
Purpose: We describe the effectiveness of lacosamide as adjunctive therapy in patients with epilepsy and an intellectual disability. This information is relevant, as few data exist pertaining to this population with a high prevalence of (intractable ...
Carpay, J. A., Brenner, J., van Beek, S., Majoie, H. J. M.   +3 more
core   +1 more source

Melatonin Levels in 89 Individuals With Smith Magenis Syndrome

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2260-2272, October 2026.
ABSTRACT In patients with Smith–Magenis syndrome (SMS), an inverted circadian rhythm of melatonin (MT) contributes to the sleep disturbance. Standard treatment of sleep disturbance with MT often leads to extremely high daytime MT levels, resulting in even more sleep disorders. We therefore retrospectively evaluated the MT data of 89 SMS patients.
Wiebe Braam, Ann C. M. Smith
wiley   +1 more source

Lacosamide as treatment for partial epilepsy: mechanisms of action, pharmacology, effects, and safety

, 2009
Christoph KellinghausDepartment of Neurology, Klinikum Osnabrück, GermanyAbstract: Lacosamide (LCM) is a novel agent that has been developed as an antiepileptic drug.
Christoph Kellinghaus
core  

Lacosamide as treatment of epileptic seizures - cost utility results for Sweden.

, 2010
Bolin K, Berggren F, Forsgren L. Lacosamide as treatment of epileptic seizures - cost utility results for Sweden. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2009.01320.x. (c) 2010 The Authors Journal compilation (c) 2010 Blackwell Munksgaard. Objectives
Berggren, Fredrik, Forsgren, L, Forsgren, Lars,, Berggren, F, Bolin, Kristian, Berggren, Fredrik,, Bolin, Kristian,, Lund University., F. Berggren, L. Forsgren, K. Bolin   +10 more
core   +1 more source

Vitamin B6 Deficiency and Status Epilepticus: A Preventable Cause of Death in People with Parkinson's Disease

Movement Disorders, EarlyView.
Karlo J. Lizarraga, Andres M. Kanner, Anthony E. Lang   +2 more
wiley   +1 more source