Results 121 to 130 of about 7,921 (224)

A Rare Case of Fatty Acid Hydroxylase‐Associated Neurodegeneration in a Pakistani Boy With a Homozygous FA2H Variant

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Fatty acid hydroxylase‐associated neurodegeneration (FAHN) is an ultra‐rare neurological disorder caused by a mutation in the FA2H gene. Defective production of this gene leads to abnormal myelin formation, which subsequently causes neurodegeneration and brain iron accumulation.
Araj Naveed Siddiqui, Yamna Naveed Siddiqui, Noor ul Huda Abbasi, Raman Kumar, Hermann Yokolo   +4 more
wiley   +1 more source

Frontal Lobe Epilepsy Presenting With Unilateral Eye Closure

Neurology and Clinical Neuroscience, EarlyView.
Yuki Mizumoto, Kazutoshi Konomatsu, Takafumi Kubota, Kazushi Ukishiro, Yosuke Kakisaka, Makoto Yoshida, Kazutaka Jin   +6 more
wiley   +1 more source

Severe Pediatric MOGAD‐Associated ADEM With Persistent Neurological Morbidity and Later‐Onset Epilepsy of Uncertain Etiology: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This report describes a 7‐year‐old boy with MOGAD presenting as severe ADEM with fever, encephalopathy, seizures, markedly elevated intracranial pressure, diffuse multifocal MRI abnormalities, and serum MOG‐IgG positivity. He required intravenous corticosteroids, plasma exchange, IVIG, and tocilizumab, followed by rehabilitation and ...
Desiree‐Anne Ramsaran, Garrett Gianneschi, Janet Elgallab   +2 more
wiley   +1 more source

Polymicrogyria and Cardiac Arrhythmia in a Neonate With Biallelic Stop‐Gain Variant in TMEM161B: Expanding the Phenotype

Prenatal Diagnosis, EarlyView.
Miriam Bertrand, Ute Grasshoff, Cornelia Wiechers, Dennis Witt, Vivien Richter, Andreas Dufke, Karl Oliver Kagan, Tobias B. Haack   +7 more
wiley   +1 more source

Peripartum Management of Vagus Nerve Stimulation and Antiseizure Medications During Two Pregnancies in a Woman With Drug‐Resistant Epilepsy: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT There are limited reports on vagus nerve stimulation (VNS) therapy during pregnancy. We report a case of two pregnancies in a woman with drug‐resistant epilepsy (DRE) managed with VNS. A woman with epilepsy underwent implantation of a VNS device because antiseizure medications (ASMs) and a lobectomy were not sufficient to control seizures ...
Motoki Ono, Ryoichi Asaka, Yasuhiro Tanaka, Chiho Fuseya, Norihiko Kikuchi, Tsutomu Miyamoto   +5 more
wiley   +1 more source

Breath Signatures of Antiseizure Medication Response and Tolerability in Adults With Epilepsy

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Breath metabolomic profiles distinguish treatment response and adverse effects in adults with epilepsy, whereas serum antiseizure medication concentrations do not. These findings support breath analysis as a non‐invasive approach to pharmacodynamic phenotyping, capturing treatment‐related metabolic states relevant to complex human disease.
Kai Fricke, Diego Manuel Baur, Kapil Dev Singh, Felix Schmidt, Kathrin Müsch, Noriane Andrina Sievi, Marco Di Donato, Anton Schmick, Silvia Ulrich, Pablo Sinues, Marian Galovic, Malcolm Kohler   +11 more
wiley   +1 more source

The Concomitant Effect of the Antiepileptic Drug Lacosamide and rTMS on an SH-SY5Y Model of Neuronal Excitability

Neurology International
Background/Objectives: Epilepsy is identified by irregular neuronal hyperexcitability, generating recurrent seizures. Despite many available pharmacological treatments, certain patients with drug-resistant epilepsy may require novel therapeutic ...
Ioannis Dardalas, Efstratios K. Kosmidis, Vasilios K. Kimiskidis, Roza Lagoudaki, Theodoros Samaras, Theodoros Moysiadis, Dimitrios Kouvelas, Chryssa Pourzitaki   +7 more
doaj   +1 more source

The Effectivety, Safety and Tolerability Profile of Lacosamide Therapy in Refractory Epilepsy: Premarketing Experience

, 2014
E, A/0000-0003-3698-8201WOS: 000408852700005Objectives: Lacosamide is a novel antiepileptic drug used in partial refractory epilepsy patients. Methods: We searched retrospectively 1100 patients who have follow up in Antalya Education and Research ...
Kutlu, Gulnihal, Aydemir, Yasemin, Gomceli, Yasemin Bicer, Erdal, Abidin, Akca, Gizem, Tokuc, Firdevs Ezgi Ucan, Genc, Fatma   +6 more
core   +1 more source

Clobazam to preserve meaningful engagement in prolonged disorder of consciousness with concurrent seizure disorder

PM&R, EarlyView.
Tatiana Bernstein, Zachary Miklja, Tiffany Wood, Joshua Startup   +3 more
wiley   +1 more source

Cenobamate use in super‐refractory status epilepticus: A report of three cases

Epileptic Disorders, Volume 28, Issue 5, Page 1661-1668, October 2026.
Abstract Objectives Super‐refractory status epilepticus (SRSE) is a neurological emergency with high morbidity and mortality. Cenobamate, a novel antiseizure medication, may be helpful in managing SRSE, but evidence is limited. Methods This retrospective case series reports the use of cenobamate as add‐on therapy in the management of three cases of ...
Marina Romozzi, Juan Luis Alcala‐Zermeno, Antonio Funcis, Federico Tosto, Marta Piccioli, Luigi Francesco Iannone, Riccardo Maviglia, Masahito Katsuki, Yasuhiko Matsumori, Paolo Calabresi, Raffaele Iorio, Catello Vollono   +11 more
wiley   +1 more source