Results 31 to 40 of about 7,921 (224)

Efficacy of Lacosamide Therapy in Focal Onset Refractory Epilepsy of Childhood: A Single Center Experience

open access: yesJournal of Behçet Uz Children's Hospital, 2021
Objective: Treatment of childhood refractory epilepsy is a challenge for clinicians. Lacosamide is a new generation antiepileptic drug which is being used for focal onset seizures of adults and children.
Halil Ural Aksoy   +5 more
doaj   +1 more source

The effectiveness of antiepileptic drug treatment in glioma patients: lamotrigine versus lacosamide [PDF]

open access: yes, 2021
Purpose Optimal treatment with antiepileptic drugs (AEDs) is an important part of care for brain tumor patients with epileptic seizures. Lamotrigine and lacosamide are both examples of frequently used non-enzyme inducing AEDs with limited to no drug-drug
Opijnen, M.P. van   +7 more
core   +1 more source

A case of auditory disturbance caused by lacosamide

open access: yesEpilepsy and Behavior Case Reports, 2019
We report a case of auditory disturbance in an adult female that developed after starting lacosamide treatment for epilepsy. While carbamazepine is known to change auditory pitch perception in some patients, that has not been previously reported as a ...
Mihoko Kawai, Kousuke Kanemoto
doaj   +1 more source

Lacosamide-induced excessive laughing in a patient with Lennox–Gastaut syndrome

open access: yesEpilepsy and Behavior Case Reports, 2018
Lacosamide is one of the third-generation antiseizure drugs that block voltage-gated sodium channels by enhancing slow inactivation. The most common adverse effects of lacosamide include dizziness, headache, nausea, vomiting, diplopia, fatigue, and ...
Hussein Algahtani   +2 more
doaj   +1 more source

Successful treatment of childhood prolonged refractory status epilepticus with lacosamide [PDF]

open access: yes, 2011
Prolonged, refractory status epilepticus is a rare clinical syndrome that is associated with severe morbidity and mortality. Lacosamide is a newly approved medication for treatment of partial onset seizures in adults, which has a novel mechanism of ...
Tennison, Michael   +7 more
core   +1 more source

Lacosamide add-on Treatment in Refractory Focal Epilepsy: The Experience of a Single Tertiary Center [PDF]

open access: yes, 2020
Objectives:Lacosamide is a third-generation antiepileptic agent that selectively enhances slow inactivation of sodium channels that take part in generation and propagation of action potentials and results in the diminution of neuronal excitability ...
Bülent Oğuz GENÇ   +6 more
core   +1 more source

Safety and efficacy of lacosamide versus phenytoin for refractory seizures in neurosurgical patients

open access: yesBMJ Neurology Open, 2021
Background Postoperative neurosurgical patients have increased risk of seizures. Traditional anti-epileptics, such as phenytoin, are not always effective and cause adverse effects.
Sarah Schaidle   +2 more
doaj   +1 more source

Lacosamide in Pediatric Status Epilepticus [PDF]

open access: yes, 2017
Investigators from Baylor College of Medicine studied the efficacy of lacosamide in pediatric status epilepticus (SE)
Juan A. Piantino
core   +1 more source

Neonatal Cardiac Arrest Following Lacosamide Treatment: A Case Report

open access: yes, 2023
Lacosamide is an antiepileptic drug with FDA approval for treatment of partial-onset seizures in patients above the age of 1 month. Lacosamide works by selective enhancement of proteins which induce preferential slow promotion of sodium channels to the ...
Melissa Ann Huberman   +5 more
core   +1 more source

CLINICAL AND ECONOMIC EVALUATION OF LACOSAMIDE IN PATIENTS WITH PARTIAL EPILEPSY

open access: yesФармакоэкономика, 2016
Aims of study: 1) development of a model for forecasting of impact of Lacosamide administration for antiseizure therapy of local convulsions in patients, who are resistant to previous antiseizure therapy, for the account of healthcare and social security
E. A. Pyadushkina, M. Yu. Frolov
doaj   +1 more source

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