Results 41 to 50 of about 7,921 (224)
Heliyon, 2023 Objective: We evaluated adherence to and 1-year persistence of two third-generation anti-seizure medications (ASMs), lacosamide and perampanel, in adult patients with focal epilepsy, compared with lamotrigine and levetiracetam.
Siming Chen +6 more
doaj +1 more source
Lacosamide-Induced Bullous Pemphigoid
Annals of Internal Medicine: Clinical CasesDrug-induced bullous pemphigoid (DIBP) is a rare condition commonly associated with polypharmacy. Unlike several other antiepileptic drugs, lacosamide has not been linked previously to the development of bullous pemphigoid (BP).
Jasmine Dugal +4 more
doaj +1 more source
Clinical Experience with Adjunctive Lacosamide in Adult Patients with Focal Seizures
, 2017 Objectives: The aim of this study was to report first clinical experience in Turkey using lacosamide (LCM) as adjunctive therapy in patients with focal onset ...
Ilhan Algin, Demet +6 more
core +1 more source
Effects of Lacosamide in Cerebral Tuberculoma-Induced Nonconvulsive Status Epilepticus: Case Report
, 2017 Nonconvulsive status epilepticus (NCSE) is characterized by unexplained changes in behavior and mental status accompanied with continuous seizure activity seen on electroencephalography (EEG).
Ilhan Algin, Demet +7 more
core +1 more source
Acute toxic leucoencephalopathy following protonitazene ingestion
British Journal of Clinical Pharmacology, EarlyView.Background Distribution of illicit counterfeit alprazolam containing the highly potent synthetic opioid‐receptor agonist protonitazene recently resulted in a number of severe overdoses in Ireland. We report three cases that presented to our hospital, within 6 weeks of one another, following ingestion of illicitly‐sourced alprazolam.
Ruadhan O'Laoi +5 more
wiley +1 more source
Lacosamide adjunctive therapy for partial-onset seizures: a meta-analysis [PDF]
PeerJ, 2013 Background. The relative efficacy and safety of lacosamide as adjunctive therapy compared to other antiepileptic drugs has not been well established.Objective.
Sonja C. Sawh +3 more
doaj +2 more sources
Examining the Clinical Utility of Lacosamide
, 2010 Lacosamide is an antiepileptic drug (AED) approved for the adjunctive treatment of partial-onset seizures in adults. Completed phase II/III clinical trials of lacosamide provide a valuable opportunity to evaluate clinically relevant aspects of the ...
Nathan B. Fountain +17 more
core +1 more source
Annals of the Child Neurology Society, EarlyView.ABSTRACT Introduction GRIA2 encodes the GluA2 ionotropic α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPA) receptor subunit. Pathogenic GRIA2 variants cause epilepsy, developmental delay, and neurobehavioral disorders. Characterizations of clinical features, including seizure types and their treatments, in patients with GRIA2‐related ...
Sai Srihitha Dommata +9 more
wiley +1 more source
Bulletin of Faculty of Pharmacy Cairo University, 2019 Validation of stability indicating RP-UPLC assay method for the determination of Lacosamide and Quetiapine fumarate in pharmaceutical products. This method has showed a high degree performance in separation and quantification of Lacosamide and Quetiapine
Tene Sivaganesh +5 more
doaj +1 more source
Epileptic Disorders, EarlyView.Abstract Objective The postictal state is a major yet underrecognized component of the epilepsy burden. We aimed to develop a structured patient‐reported instrument to quantify postictal recovery, characterize its multidimensional burden, and identify demographic, clinical, psychiatric, and treatment‐related factors associated with postictal severity ...
Ionuț‐Flavius Bratu +2 more
wiley +1 more source