Results 151 to 160 of about 68,227 (310)

Cefdinir reprograms Gram‐positive bacteria to synergize with lysozyme against superbugs

mLife, EarlyView.
Abstract Multidrug‐resistant (MDR) bacteria pose a critical global health threat, urgently requiring solutions. Cefdinir, the highest‐selling third‐generation cephalosporin but one now facing clinical obsolescence due to escalating resistance, is conventionally classified as a nascent cell wall synthesis inhibitor.
Qi Zhang, Yang Yang, Shuqi Li, Zhao Liu, Chun‐Kit Lee, Chi‐Bun Ko, Qian Zhao   +6 more
wiley   +1 more source

Likelihood of aggressive PK/PD target attainment of continuous-infusion beta-lactams during the first week of treatment of febrile neutropenia: findings from a 1-year prospective, monocentric study in onco-haematological patients. [PDF]

J Antimicrob Chemother
Cojutti PG, Toschi A, Pasquini Z, Paolini S, Maffini E, Bonifazi F, Zinzani PL, Giannella M, Viale P, Pea F.   +9 more
europepmc   +1 more source

Thermoplastic‐Resin Transfer Molding Technology: Development and Challenges Toward Industrialization

Polymer Composites, EarlyView.
Illustration of the key aspects involved in the manufacture of thermoplastic composites by T‐RTM highlighting the relationships between raw materials, resin mixing strategies, polymerization parameters, and processing equipment ranging from laboratory to industrial scale. ABSTRACT Driven by increasingly stringent international environmental regulations,
Filipe P. Martins, Paulo S. Lima, Ricardo Torcato, Laura Santos, J. M. Oliveira   +4 more
wiley   +1 more source

Base-Promoted C→N Carbonyl Shift Enables One-Step Access to aza-β-Lactams from α-Heteroaryl-α-amino Esters. [PDF]

Org Lett
Kristek J, Št'astná N, Pospíšil J.
europepmc   +1 more source

Statistical evaluation of nylon chemical recycling through acidolysis

Polymer International, EarlyView.
Sustainable PA6 recycling through acidolysis enabled temperature‐driven depolymerization, modeled by regression analysis. Recycled products successfully replaced up to 30% monomer while preserving PA6 chemical composition or crystalline structure. Abstract This study focuses on the sustainability of plastics reporting the recycling of polyamide (PA ...
Diego Penzo, Bruno Godinho, Gabriele Rossignolo, Michele Modesti, Artur Ferreira, Alessandra Lorenzetti, Ana Barros‐Timmons, Nuno Gama   +7 more
wiley   +1 more source

Chemoproteomic Elucidation of β-Lactam Drug Targets in <i>Mycobacterium abscessus</i>. [PDF]

ACS Infect Dis
Devlin KL, Hutchinson E, Leach DT, Gorham LJ, Nelson WC, Lamichhane G, Lin VS, Beatty KE.   +7 more
europepmc   +1 more source

Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems

The Chemical Record, EarlyView.
Main nanocarriers employed to enhance the bioavailability and transport of organoselenium compounds. The image illustrates the key interaction forces that stabilize these organoselenium species in solution, enabling their application in drug delivery systems, catalysis, photoelectronic devices, and sensing technologies. In recent years, publications on
Romelly Eugenia Rojas Ramírez, Tielle Moraes de Almeida, Daiani Canabarro Leite, Gilson Zeni   +3 more
wiley   +1 more source

Acid-dependent beta-lactam resistance in <i>Klebsiella pneumoniae</i> is mediated by paralogous class B PBPs and the class A PBP, PBP1b. [PDF]

mBio
Beagle S, Levin PA.
europepmc   +1 more source

Antimicrobial Residues in a Key Cerrado River: Distribution, Persistence, and Effects on Zebrafish Embryo‐Larval Development

Environmental Toxicology, EarlyView.
ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão, Igor Romeiro dos Santos, Jerônimo Raimundo de Oliveira Neto, Flávio Olimpio Sanches Neto, Felipe Cirqueira Dias, Jéssyca Moreira Morais, Lorranny Pereira de Assis Valadares, Naiara Raica Lopes de Oliveira, Mirelle Garcia Silva Bailão, Luiz Carlos da Cunha, Valter Henrique Carvalho‐Silva, Thiago Lopes Rocha, Elisa Flávia Luiz Cardoso Bailão   +12 more
wiley   +1 more source

DBU-Promoted Cascade Cyclization/Thiolation of β-Enamino Diketones to 5-Sulfenylated 3-Hydroxy-γ-lactams. [PDF]

J Org Chem
Poletto J, Willig JCM, Camargo JNA, Rosa FA.   +3 more
europepmc   +1 more source