Results 171 to 180 of about 74,505 (292)

Photocatalytic Annulation of Primary Amines to δ-Lactams: Access to Privileged (Spiro)piperidine Space. [PDF]

Org Lett
Turner-Dore JC, Bell-Tyrer JJ, Askey HE, Richards DL, Polishchuk O, Datsenko OP, Cadge JA, Ciaccia M, Mykhailiuk PK, Cresswell AJ.   +9 more
europepmc   +1 more source

UV mutagenesis‐enhanced Streptomyces nogalater produces a novel streptothricin‐like compound with strong activity against cabbage soft rot

Pest Management Science, EarlyView.
UV mutagenesis of Streptomyces sp. KRA0514‐6 yielded HL‐3, a novel streptothricin‐like compound (C17H29N7O8) with N‐methylglycine replacing β‐lysine, achieving 100% cabbage soft rot control at >1 ppm concentration. Abstract BACKGROUND A total of 1000 soil‐derived actinomycetes were isolated and screened for antibacterial activity against Pectobacterium
Young Sook Kim, Mirjalol Umurzokov, Hae Young Kim, Chun‐Zhi Jin, Eun Ae Kim, Kwang Min Cho   +5 more
wiley   +1 more source

Multipronged Cell Wall-Targeting Converts Ineffective Antibiotics into a Potent Regimen against Mycobacterium abscessus. [PDF]

ACS Infect Dis
Pee CJE, Santos MD, Pethe K.
europepmc   +1 more source

Polymersome‐Enabled Multimodal Delivery of Tobramycin and Doripenem for Targeted Eradication of Pseudomonas aeruginosa Biofilms in Chronic Rhinosinusitis

Small, EarlyView.
Schematic representation of diffusion‐based versus pH‐triggered drug release within a bacterial biofilm. In diffusion‐based systems, drug cargo is gradually released independent of local pH, resulting in rapid burst release and reduced sustained concentrations.
Amalie Kjær Andresen, Matteo Tollemeto, Alexander B. Cook, Claus Sternberg, Yudong Li, Claus Moser, Lars Jelsbak, Jan C. M. Van Hest, Anja Boisen, Line Hagner Nielsen   +9 more
wiley   +1 more source

Synthesis of bicyclic lactams using novel Schmidt reactions

ARKIVOC, 2003
Mike Casey, John A. Donnelly, Joseph C. Ryan, Satoshi Ushioda   +3 more
doaj   +1 more source

Antibacterial Effect of the In Vitro Interaction Between Clotrimazole and Chlorhexidine Against Staphylococcus pseudintermedius With Known Resistance Patterns Isolated From Canine Pyoderma. [PDF]

Vet Med Sci
Gallegos-Torres B, Alfonseca-Silva E, Ledesma-Carrasco C, Aquino-Díaz I.   +3 more
europepmc   +1 more source

Photo‐Switched Catalytic Amyloids

Small, EarlyView.
Photo‐switched reversible hierarchical assembly of catalytic amyloid fibrils is accomplished by mixing an amphiphilic cross‐ß peptide with a merocyanine photo switch. The peptide monomers, comprising phenylalanine‐lysine repeats, do not self‐assemble in water because of the electrostatic repulsion.
Shubhra Kanti Bhaumik, Sisira Mambram Kunnath, Elad Arad, Einat Nativ‐Roth, Arunavo Chatterjee, Albert Batushansky, Nitzan Shauloff, Hanna Rapaport, Raz Jelinek   +8 more
wiley   +1 more source

Likelihood of aggressive PK/PD target attainment of continuous-infusion beta-lactams during the first week of treatment of febrile neutropenia: findings from a 1-year prospective, monocentric study in onco-haematological patients. [PDF]

J Antimicrob Chemother
Cojutti PG, Toschi A, Pasquini Z, Paolini S, Maffini E, Bonifazi F, Zinzani PL, Giannella M, Viale P, Pea F.   +9 more
europepmc   +1 more source

Programmable 3D Microfluidics Reveals Motility‐Driven Antibiotic Resistance Evolution in Gradients

Small, EarlyView.
Using a programmable microfluidic platform, this study shows that bacterial motility is crucial for resistance development in heterogeneous antibiotic landscapes. Motile Escherichia coli randomly migrates along antibiotic gradients, and sufficient movement is required for resistance to emerge.
Xiaobo Li, Jianan Yin, Yanqing Song, Andrew Glidle, William Sloan, He Huang, Maggie Cusack, Cindy J. Smith, Huabing Yin   +8 more
wiley   +1 more source

The phenotypic landscape of the model firmicute <i>Bacillus subtilis</i>. [PDF]

Proc Natl Acad Sci U S A
Kim LM, Koo BM, Burkhart HN, Vollmer D, Vollmer W, Todor H, Gross CA.   +6 more
europepmc   +1 more source