Asymmetric Synthesis and Antimicrobial Activity of Some New
: Reaction of the amino acid D-phenylalanine ethyl ester (4) with cinnamaldehyde gave chiral Schiff base 5, which underwent an asymmetric Staudinger [2+2] cycloaddition reaction with phthalimidoacetyl chloride to give the monocyclic β-lactam 6 as a ...
Bicyclic Β-lactams +3 more
core
ABSTRACT Aim To synthesise evidence on the effectiveness, harms and benefits of different approaches to prevent early‐onset Group B Streptococcus (EOGBS) and identify gaps in short and longer‐term outcomes. Methods A two‐phase rapid review. Phase 1 included an overview of systematic reviews (SRs).
Pauline Campbell +12 more
wiley +1 more source
Postsurgical infection with carbapenemase-producing Enterobacterales in a 45-year-old woman. [PDF]
Leung E, Fattouh R, Verway M, Tan C.
europepmc +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Correction: Molecular resistance mechanisms to newly approved antibiotics (2017-2025) in WHO priority pathogens. [PDF]
Frontiers Production Office.
europepmc +1 more source
Quality and Consistency of Penicillin Allergy Delabelling Guidelines: A Systematic Review
Eighteen penicillin allergy delabelling guidelines from 12 countries were reviewed. There is consensus for staged risk‐based testing, with emerging support for direct oral challenge in low‐risk patients and expanded non‐specialist roles. Overall guideline quality was low, with major gaps in methodological rigour, stakeholder involvement, and ...
Jessie He +8 more
wiley +1 more source
Comparative effectiveness of oral antibiotics to treat uncomplicated urinary tract infections in male outpatients. [PDF]
Madaras-Kelly K, Boyd J, Bond L.
europepmc +1 more source
NCY-1 β-Lactamase Activity Correlates With Antimicrobial Susceptibility of a Clinical Strain of Nocardia cyriacigeorgica. [PDF]
Couston J +8 more
europepmc +1 more source
ABSTRACT The present guideline updates the initial ESCD patch testing guideline, summarizing all aspects of patch testing for the diagnosis of contact allergy in patients suspected of suffering, or having been suffering, from allergic contact dermatitis or other delayed‐type hypersensitivity skin and mucosal conditions. Sections with brief descriptions
Wolfgang Uter +23 more
wiley +1 more source
Association of antibiotic type and timing with sepsis mortality using target trial emulation. [PDF]
Li J, Zhao M, He Q.
europepmc +1 more source

