Abstract Background Disease in primary care frequently represents a surveillance blind spot, particularly for diseases affecting farm animals. Methods Electronic health records (EHRs) were collected from four farm animal veterinary practices in Wales (February 2024‒January 2025) as part of a pilot study.
Beverley Hopkins +8 more
wiley +1 more source
Synergistic activity of dual β-lactams against <i>Mycobacterium avium</i> complex. [PDF]
Shin E +6 more
europepmc +1 more source
Nacubactam: a review on mechanistic insights and therapeutic promise for combating β-lactam resistance among multidrug-resistant Gram-negative pathogens. [PDF]
Kumar D +4 more
europepmc +1 more source
Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy
DeAns with defined nanoscale structure reveal that conjugate size and determinant density govern IgE‐mediated effector‐cell activation in AX allergy. All DeAn generations bind to sIgE in inhibition immunoassay, but only larger DeAns trigger FcεRI‐dependent responses in mouse MC, huRBL‐2H3, and LUVA cells.
Amene Tesfaye Ayane +12 more
wiley +1 more source
Antibiotics and probiotics differentially shape immunotherapy outcomes in non-small cell lung cancer. [PDF]
Ma S +11 more
europepmc +1 more source
Successful Application of the Mast Cell Activation Test in Immediate Hypersensitivity to Amoxicillin
This study included 28 amoxicillin‐allergic patients and 11 healthy exposed controls. Mast cells were differentiated from CD34+ progenitors over 8 weeks using cytokine cocktails. The mast cell activation test involved sensitization with patient or control sera and stimulation with free amoxicillin or G4/G5‐AXO dendrimers with successfully activated ...
Jose A. Céspedes +11 more
wiley +1 more source
Butadienyl Ketene: An Unexplored Intermediate in Organic Synthesis
Maninderjeet K. Mann +3 more
doaj +1 more source
Highly stereoselective synthesis of allylic β-lactams <i>via</i> enzymatic C(sp<sup>3</sup>)-H amidation. [PDF]
Jafari NZ +4 more
europepmc +1 more source
Hypersensitivity to Excipients in Drugs: An EAACI Position Paper
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey +10 more
wiley +1 more source
Utilizing whole genome sequencing data for machine learning driven prediction of antibiotic resistance in <i>Escherichia coli</i>. [PDF]
Wan F +6 more
europepmc +1 more source

