Results 231 to 240 of about 68,227 (310)

Systematic Review of Intravenous Ceftriaxone Administration in Animals

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
ABSTRACT Background Ceftriaxone is an antibiotic frequently prescribed in veterinary medical practice due to its effectiveness against several pathogenic microorganisms responsible for diseases in different animal species. Objective To select scientific articles from the academic databases PubMed and Web of Science that analysed the pharmacokinetic ...
Paula Maria Fernandes de Vasconcelos, Gabriel de Brito Rodrigues, Michel Leandro de Campos   +2 more
wiley   +1 more source

Photochemical Cyclization of Tertiary Buta-2,3-dienamides to β-Lactams Upon Triplet Energy Transfer. [PDF]

Angew Chem Int Ed Engl
Hofer J, Bertrams MS, Kerzig C, Bach T.
europepmc   +1 more source

Phenylalanine Versus Tyrosine (Pos. 367/332 in MCT1/MCT4) in the Substrate Binding Site Defines Affinity and Preferred Directionality of Human Monocarboxylate Transporters 1–4

Acta Physiologica, Volume 242, Issue 7, July 2026.
ABSTRACT Aim Human monocarboxylate transporters 1–4, MCT, are key for the lactate/H+ exchange between glycolytic and oxidative cancer cells, white and red muscle fibers, or in the astrocyte‐neuron shuttle. The common MCT transport mechanism involves three conserved residues, that is, a substrate‐attracting Lys and a conformation‐locking Asp/Arg salt ...
Maike Menzel, Ioana‐Daniela Dumitru, Josh Peters, Jan‐Bernd Hövener, Andrey N. Pravdivtsev, Ana‐Nicoleta Bondar, Eric Beitz   +6 more
wiley   +1 more source

Raising the Bar of PK/PD Target Attainment of Beta-Lactams in Daily Clinical Practice: An Effective Strategy to Overcome Resistance Development to Novel Beta-Lactams? [PDF]

Infect Dis Rep
Gatti M, Pea F.
europepmc   +1 more source

Drugs that act on both G protein‐coupled receptors (GPCRs) and kinases: potentiation of effects, side effects and general aspects of drug pleiotropy

British Journal of Pharmacology, Volume 183, Issue 13, Page 3471-3483, July 2026.
Abstract Background A drug designed for a specific target often interacts with multiple targets, either unintentionally or as part of its intended mechanism of action. This has been called pharmacological pleiotropy or polypharmacology. There are key endogenous ligands such as ATP, GABA and glutamate that act on various proteins in humans. Furthermore,
Hampus Ljunggren, Aleksandr Sokolov, Flavio Ballante, Robert Fredriksson, Francisco Lagunas‐Rangel, Alexander S. Hauser, Stefan Knapp, Jörgen Jonsson, Helgi B. Schiöth   +8 more
wiley   +1 more source

Bayesian network models to assess antimicrobial resistance patterns of Streptococcus suis isolated from swine production systems in the United States between 2014-2021. [PDF]

PLoS Comput Biol
Rupasinghe R, Morgan Bustamante BL, Robbins RC, Clavijo MJ, Martínez-López B.   +4 more
europepmc   +1 more source

Global resistome architecture of Escherichia coli across human and animal hosts: analysis of 9,696 genome. [PDF]

BMC Microbiol
Azour A, Matar GM, Bilen M.
europepmc   +1 more source

Enzymatic activity of PBP1B is required for growth rate-independent ppGpp-mediated resistance to PBP2 inhibitors in E. coli. [PDF]

J Bacteriol
Anderson SE, Mack IE, Levin PA.
europepmc   +1 more source

Penicillin-Binding Proteins in Streptococcus agalactiae and Their Association with Reduced Penicillin Susceptibility: An Overview. [PDF]

Antibiotics (Basel)
Nagao Ferreira L, Pimentel Hecht BA, Dos Santos LS, Nagao PE.   +3 more
europepmc   +1 more source