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The Onset of Lactase Persistence in Europe [PDF]

Human Heredity, 2013
The genomic region containing the lactase (LCT) gene shows one of the strongest signals of positive selection in Europeans, detectable using a range of approaches including haplotype length, linked microsatellite variation and population-differentiation-based tests. Lactase is the enzyme that carries out the digestion of the milk sugar lactose.
openaire +2 more sources

Diversity of lactase persistence in African milk drinkers

Human Genetics, 2015
The genetic trait of lactase persistence is attributable to allelic variants in an enhancer region upstream of the lactase gene, LCT. To date, five different functional alleles, −13910*T, −13907*G, −13915*G, −14009*G and −14010*C, have been identified ...
B. L. Jones +10 more
semanticscholar +1 more source

Genetic adult lactase persistence is associated with risk of Crohn's Disease in a New Zealand population

BMC Research Notes, 2010
Background Mycobacterium avium subspecies paratuberculosis (MAP) is an infective agent found in ruminants and milk products, which has been suggested to increase the risk of gastrointestinal inflammation in genetically susceptible hosts.
Morgan Angharad R +6 more
doaj +1 more source

Human small-intestinal β-galactosidases. Separation and characterization of one lactase and one hetero β-galactosidase [PDF]