Results 51 to 60 of about 3,547 (167)
Lactose intolerance is a condition where the body cannot digest lactose due to a deficiency of the lactase enzyme in the digestive system, leading to various health issues and indirectly increasing the risk of stunting.
Mike Permata Sari +2 more
doaj +1 more source
Genetics of lactase deficiency in Russia
The ability to digest lactose in adulthood is caused by a genetic mutation that emerged following the domestication of cattle approximately 10 000 years ago. However, many adults retain primary lactase deficiency - the ancestral phenotype characterized by a decline in lactase enzyme activity after weaning.
E.V. Kovalenko +8 more
openaire +2 more sources
Homo sapiens, industrialisation and the environmental mismatch hypothesis
ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley +1 more source
Features of endocrine status in obese children and polymorphisms of the lactase gene
Background. Obesity is an imbalance of immunocytokine and neuroendocrine regulation of energy metabolism with excessive accumulation of adipose tissue in the body accompanied by the formation of a chronic proinflammatory immune response associated with ...
A.A. Nikulina
doaj +1 more source
Pembrolizumab for Early‐Stage Triple‐Negative Breast Cancer: KEYNOTE‐522 Japan Subgroup Analysis
In the global, phase 3 KEYNOTE‐522 study of high‐risk early‐stage triple‐negative breast cancer (TNBC), neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab improved efficacy outcomes versus neoadjuvant chemotherapy alone. In this analysis of Japanese participants from KEYNOTE‐522, neoadjuvant pembrolizumab plus chemotherapy ...
Masato Takahashi +16 more
wiley +1 more source
Hypolactasia associated with severe iron-deficiency anemia has been reported in several studies. The objective of the present study was to determine whether hypolactasia is associated with the degree and duration of iron-deficiency anemia.
M.R. Vieira +2 more
doaj +1 more source
Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska +8 more
wiley +1 more source
Nezgoda I., Naumenko O. Rotavirus infection in children with different variants allelic polymorphism C> T 13910 gene LCT = Перебіг ротавірусної інфекції у дітей з різними варіантами алельного поліморфізму С >Т 13910 гена лактази.
I. Nezgoda, O. Naumenko
doaj +3 more sources
Dietotherapy in children with obesity associated with adult lactase deficiency
Background. Excess lactose in the infant’s nutrition, especially in combination with adult lactase deficiency (С/C 13910 genotype), promotes the persistence of a chronic inflammatory process associated with the formation of obesity-complicated insulin ...
A.E. Abaturov +3 more
doaj +1 more source
Molecular Pharming: Advances, Applications, and Future Prospects in Biotechnology and Medicine
ABSTRACT Genetically engineered plants incorporate the use of a novel bioreactor known as molecular pharming, which has a transformative view on the pharmaceutical industry. The technique enables mass production, at a low cost, and reproducibly of a large number of different protein‐based drugs, vaccines, and industrial enzymes. This review‐based study
Md. Hridoy Ahmed +13 more
wiley +1 more source

