Results 51 to 60 of about 468,567 (186)

Four novel mutations in the lactase gene (LCT) underlying congenital lactase deficiency (CLD)

BMC Gastroenterology, 2009
Background Congenital lactase deficiency (CLD) is a severe gastrointestinal disorder of newborns. The diagnosis is challenging and based on clinical symptoms and low lactase activity in intestinal biopsy specimens.
Höglund Pia, Catassi Carlo, Gijsbers Carolien, Routi Taina, Freddara Roberta, Torniainen Suvi, Savilahti Erkki, Järvelä Irma   +7 more
doaj   +1 more source

Refining Genetic Instruments for Dietary Intake Mendelian Randomization Using Phenome‐Wide Association Studies

Genetic Epidemiology, Volume 50, Issue 8, December 2026.
ABSTRACT Most Mendelian randomization (MR) of dietary intake use the full set of genome‐wide significant (GWS) variants in the instrumental variable (IV), likely biasing causal estimates due to pleiotropy. To characterize the common methods to handle pleiotropy in dietary intake MR, we conducted a scoping review of the literature on dietary intake MR ...
Kristen J. Sutton, Julie E. Gervis, Moomal Jatoi, Liang‐Dar Hwang, Audrey E. Hendricks, Debashis Ghosh, Kenneth E. Westerman, Joanne B. Cole   +7 more
wiley   +1 more source

Comparative Pharmacokinetics and Safety of Orally Disintegrating and Conventional Tablet Formulations of Zastaprazan in Healthy Subjects

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Zastaprazan, a potassium‐competitive acid blocker, has been developed as an orally disintegrating tablet (ODT) to improve administration flexibility. This study evaluated the pharmacokinetics and safety of a single 20 mg dose of Zastaprazan ODT administered with or without water compared with the conventional tablet in healthy volunteers.
Hyung‐Gun Kim, Seunghyun Kang, Sunyoung Min, Heejoo Hong, Moonjung Bae   +4 more
wiley   +1 more source

Treatment of lactase deficiency in children’s obesity with genotype C/C 13910 of lactase gene [PDF]

, 2019
Introduction: Excess lactose in the diet of modern man causes the development of not only lactase deficiency, but it can be a factor that contributes to obesity. The aim: To study associations between obesity and genotype C/C 13910 of lactase gene (LCT)
Nikulina, Anna A., Stepanov, Yuri M., Abaturov, Alexandr Ye.   +2 more
core   +3 more sources

Sources, Transmission, and Control of Salmonella in Vertically Integrated Broiler Chicken Production: Farm, Hatchery, and Processing Plant

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT Salmonella remains one of the most important foodborne pathogens associated with poultry products, despite substantial progress in processing hygiene and antimicrobial interventions. This review critically examines the sources, transmission routes, and control strategies for Salmonella in vertically integrated broiler production systems ...
Deepak Subedi, Bharath Mallavarapu, Pranita Patil, Abhisek Niraula, Milan Kandel, Sanjay Kumar, Amit Kumar Singh   +6 more
wiley   +1 more source

Lactase Deficiency in Children With Cystic Fibrosis

Педиатрическая фармакология, 2017
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Irina G. Gordeeva
doaj   +1 more source

Duodenal stricture and portal gas accumulation secondary to ulcerative, fibronecrotising duodenitis in a foal

Equine Veterinary Education, Volume 38, Issue 10, Page e665-e670, October 2026.
Summary Gastroduodenal ulcer disease with secondary stricture formation of the proximal duodenum and portal gas accumulation is described in a neonatal foal. Conventional diagnostics were performed to reach a diagnosis, including gastroscopy, ultrasonography and positive contrast radiography. In addition, a post‐mortem CT was acquired with the contrast
R. F. Dash, G. Manso‐Diaz, A. Suarez‐Bonnet, M. Hewetson   +3 more
wiley   +1 more source

Bioengineered Extracellular Vesicles Mitigate Neuroinflammation by Neutralizing Pneumolysin and Delaying Disease Onset in Experimental Pneumococcal Meningitis

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Bacterial meningitis is a life‐threatening neurological disorder frequently caused by a Streptococcus pneumoniae (the pneumococcus) infection of the brain. Standard treatment consists of antibiotics to eliminate bacteria and dexamethasone to reduce inflammation.
Kristine Farmen, Doste R. Mamand, Miguel Tofiño‐Vian, Georgia Yfanti, Xiuming Liang, Houze Zhou, Vicky W. Q. Hou, Samir El Andaloussi, Oscar P. B. Wiklander, Federico Iovino   +9 more
wiley   +1 more source

Primary Lactase Deficiency: Genetic or Acquired?

Gastroenterology, 1970
From a critical review of the literature, it would appear that, in animals, intestinal lactase is an adaptive enzyme, with adaptation occurring in 5–8 weeks. In man, short-term attempts at adaptation have not been successful, although a fall in lactase activity or lactose absorption has been found after substrate withdrawal in some subjects.
T D, Bolin, A E, Davis
openaire   +3 more sources

Recent and Promising Strategies for Robust, Sustainable, and Cost‐Friendly Production of Yogurt With Superior Quality

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 5, September 2026.
ABSTRACT Yogurt is one of the most technologically mature fermented dairy products on the market, traditionally prepared using the two lactic acid bacteria (LAB) Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus. Global demand for yogurt continues to rise, driven by consumer interest in healthy, high‐protein diets with as few ...
Shuangqing Zhao, Belay Tilahun Tadesse, Christian Solem   +2 more
wiley   +1 more source