Results 111 to 120 of about 326,261 (230)

Dairy consumption and cardiometabolic diseases: systematic review and updated meta-analyses of prospective cohort studies [PDF]

open access: yes, 2018
Purpose of Review Dairy products contain both beneficial and harmful nutrients in relation to cardiometabolic diseases. Here, we provide the latest scientific evidence regarding the relationship between dairy products and cardiometabolic diseases by ...
A Hruby   +82 more
core   +3 more sources

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, Volume 19, Issue 6, Page 1737-1750, June 2025.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

The Role of Lactose Tolerance in Pre-Colonial Development [PDF]

open access: yes
This paper establishes a link between natural selection since the Neolithic Revolution and economic conditions in the pre-colonial era. The ability to digest milk, or to be lactose tolerant, is conferred by a gene variant, which is unequally distributed ...
Charles J. Cook
core  

The genetic variation of lactase persistence alleles in northeast Africa

open access: yesbioRxiv, 2020
Lactase persistence (LP) is a well-studied example of a Mendelian trait under selection in some human groups due to gene-culture co-evolution. We investigated the frequencies of genetic variants linked to LP in Sudanese and South Sudanese populations ...
N. Hollfelder   +4 more
semanticscholar   +1 more source

Microbiota in Gut‐Heart Axis: Metabolites and Mechanisms in Cardiovascular Disease

open access: yesComprehensive Physiology, Volume 15, Issue 3, June 2025.
Influence of Dietary and Lifestyle Factors on Gut Microbiota and Cardiovascular Health. ABSTRACT Emerging evidence highlights the pivotal role of gut microbiota in regulating cardiovascular health and disease. The gut microbiota, a diverse community of microorganisms residing in the gastrointestinal tract, interacts with its host through metabolites ...
Narendra Kondapalli   +4 more
wiley   +1 more source

High frequency of lactose intolerance in a prehistoric hunter-gatherer population in northern Europe

open access: yesBMC Evolutionary Biology, 2010
Background Genes and culture are believed to interact, but it has been difficult to find direct evidence for the process. One candidate example that has been put forward is lactase persistence in adulthood, i.e. the ability to continue digesting the milk
Holmlund Gunilla   +7 more
doaj   +1 more source

Strain-level analysis of Bifidobacterium spp. from gut microbiomes of adults of differing lactase persistence genotypes

open access: yesbioRxiv, 2020
One of the strongest associations between human genetics and the gut microbiome is a greater relative abundance of Bifidobacterium in adults with lactase gene (LCT) SNPs associated with lactase-non persistence (GG genotypes), versus lactase persistence ...
V. Schmidt   +4 more
semanticscholar   +1 more source

Bioavailability and Bioaccessibility of Grain Polyphenols: A Comprehensive Review

open access: yeseFood, Volume 6, Issue 3, June 2025.
ABSTRACT Phenolic compounds are highly abundant, heterogeneous substances in plant food sources, especially grains. Wheat contains chlorogenic acid, syringic acid, ferulic acid, and gallic acid, and oats contain polyphenolic compounds such as p‐hydroxybenzoic acid, caffeic acid, syringic acid, vanillic acid, and p‐coumaric acid. Corn also consists of p‐
Fatima Tariq   +9 more
wiley   +1 more source

Neolithic pots and potters in Europe: the end of ‘demic diffusion’ migratory model

open access: yesDocumenta Praehistorica, 2013
In this paper we discuss the inventions and re-inventions of ceramic technology and pot- tery dispersals in foraging and farming contexts in Eurasia.
Mihael Budja
doaj   +1 more source

The Conquest of Milk: The Rise of Lactase Persistence and the Fall of Scandinavian Hunter-Gatherers [PDF]

open access: yes, 2022
Over half of the global human population suffers from lactase nonpersistence, a condition marked by losing the ability to digest lactose after infancy. However, a minority of the global population, primarily located in Central and Northern Europe, has a ...
Mays, Nicholas
core   +1 more source

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