Results 111 to 120 of about 1,908 (139)

Lactase Persistence in Central Asia: Phenotype, Genotype, and Evolution

Human Biology, 2011
The aim of the present study is to document the evolution of the lactase persistence trait in Central Asia, a geographical area that is thought to have been a region of long-term pastoralism. Several ethnic groups co-exist in this area: Indo-Iranian speakers who are traditionally agriculturist (Tajik) and Turkic speakers who used to be nomadic herders (
Evelyne Heyer, Laure Segurel, Frédéric Austerlitz   +2 more
exaly   +4 more sources

Hypolactasia and Lactase Persistence Historical Review and the Terminology

Scandinavian Journal of Gastroenterology, 1994
Lactase (more precisely lactase-phlorizin hydrolase) is located in the brush border of the small intestinal enterocytes and is responsible for the hydrolysis of dietary lactose. The earliest studies on lactase activity in mammals were published around the turn of the century.
openaire   +2 more sources

EVOLUTION OF LACTASE PERSISTENCE

The Lancet, 1989
S F, Hoegerman, R A, Schenck
openaire   +2 more sources

The evolutionary tale of lactase persistence in humans

Nature Reviews Genetics, 2023
openaire   +2 more sources

Reevaluating the Evolution of Lactase Persistence

American Journal of Medical Genetics Part A, 2020
openaire   +2 more sources

New insights into the molecular basis of lactase non-persistence/persistence: a brief review

Drug Discoveries and Therapeutics, 2020
Yaser Rafiq Mir
exaly  

Evolutionary genetics of lactase persistence in Italy.

2012
The enzyme that hydrolyzes lactose, the main carbohydrate in milk, is lactase-phlorizin hydrolase (LCT), which is encoded by the gene LCT located on chromosome 2. Normally, in all mammals, the ability to digest lactose rapidly declines after weaning, but in some human populations this ability persists in adulthood, a condition called lactase ...
DE FANTI, SARA, SAZZINI, MARCO, SARNO, STEFANIA, GIULIANI, CRISTINA, GARAGNANI, PAOLO, Montinaro F., Anagnostou P., Destro Bisol G., LUISELLI, DONATA   +8 more
openaire   +1 more source

Strain-Level Analysis of Bifidobacterium spp. from Gut Microbiomes of Adults with Differing Lactase Persistence Genotypes

MSystems, 2020
Hagay Enav, Tim D Spector, Nicholas D Youngblut   +2 more
exaly  

The human lactase persistence-associated SNP −13910*T enables in vivo functional persistence of lactase promoter–reporter transgene expression

Human Genetics, 2012
Lin Fang, Eric Sibley
exaly  

Low prevalence of lactase persistence in Neolithic South-West Europe

European Journal of Human Genetics, 2012
Theo S Plantinga, Santos Alonso, Neskuts Izagirre   +2 more
exaly