Results 151 to 160 of about 360,868 (176)

Lactase non-persistent genotype distribution in Italy

Minerva Gastroenterology, 2017
Adult-type hypolactasia is a frequent condition of lactose malabsorption; in Europe the distribution of adult-type hypolactasia have been shown to display a North-South gradient. Genotyping for LCT-13910 C>T polymorphism has been proposed as a useful diagnostic marker of adult-type hypolactasia.
Cristina, Zadro, Savina, Dipresa, Giovanni, Zorzetti, Annalisa, Pediroda, Francesco, Menegoni   +4 more
openaire   +2 more sources

Hypolactasia and Lactase Persistence Historical Review and the Terminology

Scandinavian Journal of Gastroenterology, 1994
Lactase (more precisely lactase-phlorizin hydrolase) is located in the brush border of the small intestinal enterocytes and is responsible for the hydrolysis of dietary lactose. The earliest studies on lactase activity in mammals were published around the turn of the century.
openaire   +2 more sources

EVOLUTION OF LACTASE PERSISTENCE

The Lancet, 1989
S F, Hoegerman, R A, Schenck
openaire   +2 more sources

Reevaluating the Evolution of Lactase Persistence

American Journal of Medical Genetics Part A, 2020
openaire   +2 more sources

The evolutionary tale of lactase persistence in humans

Nature Reviews Genetics, 2023
openaire   +2 more sources

Evolutionary genetics of lactase persistence in Italy.

2012
The enzyme that hydrolyzes lactose, the main carbohydrate in milk, is lactase-phlorizin hydrolase (LCT), which is encoded by the gene LCT located on chromosome 2. Normally, in all mammals, the ability to digest lactose rapidly declines after weaning, but in some human populations this ability persists in adulthood, a condition called lactase ...
DE FANTI, SARA, SAZZINI, MARCO, SARNO, STEFANIA, GIULIANI, CRISTINA, GARAGNANI, PAOLO, Montinaro F., Anagnostou P., Destro Bisol G., LUISELLI, DONATA   +8 more
openaire   +1 more source

New insights into the molecular basis of lactase non-persistence/persistence: a brief review

Drug Discoveries and Therapeutics, 2020
Raja Amir Hassan Kuchay
exaly  

Strain-Level Analysis of Bifidobacterium spp. from Gut Microbiomes of Adults with Differing Lactase Persistence Genotypes.

MSystems, 2020
Hagay Enav, Nicholas D Youngblut, Ruth Ley   +2 more
exaly  

The human lactase persistence-associated SNP −13910*T enables in vivo functional persistence of lactase promoter–reporter transgene expression

Human Genetics, 2012
Eric Sibley
exaly  

Lactase persistence-related genetic variant: population substructure and health outcomes

European Journal of Human Genetics, 2008
Shah Ebrahim, Deborah A. Lawlor
exaly