Results 171 to 180 of about 778,516 (343)

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

Advanced Science, EarlyView.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang, Heng Yang, Xinjie Gao, Zengyu Zhang, Ruiyuan Weng, Yuchao Fei, Jiabin Su, Hanqiang Jiang, Wei Ni, Yuxiang Gu   +9 more
wiley   +1 more source

Catalytic Dehydration of Methyl Lactate to Methyl Acrylate Over Potassium-Exchanged Organic-Free Zsm-5 Zeolites

Taekyung Ryu, Seung Hyeok Cha, Dong Won Hwang   +2 more
openalex   +1 more source

EFFECT OF INCREASES IN PLASMA LACTATE CONCENTRATION ON INTRAVASCULAR HEOLYSIS DURING EXHAUSTIVE EXERCISE

, 1997
Atsuko Tsukanaka, Nobuo Matsui, Yoshihisa Umemura, Toshihiro Ishiko   +3 more
openalex   +2 more sources

Renal protection in sepsis: Is hypertonic sodium (lactate) the solution? [PDF]

, 2019
Patrick M. Honoré, Leonel Barreto Gutierrez, Herbert Spapen   +2 more
openalex   +1 more source

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

Lactation.

Bulletin of the World Health Organization, 2010
Lactation is the most energy-efficient way to provide for the dietary needs of young mammals, their mother's milk being actively protective, immunomodulatory, and ideal for their needs. Intrauterine mammary gland development in the human female is already apparent by the end of the sixth week of gestation.
openaire   +1 more source

Dose-dependent inhibition of lactate formation in COLO-2 cells – cytostatic effect.

Samo Lešnik (21073880), Janez Konc (348025), Tina Vodopivec (21402916), Katja Čamernik (21402919), Urška Karolina Potokar (21402922), Matic Legiša (222193)   +5 more
openalex   +1 more source

NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2

Advanced Science, EarlyView.
The loss of NFS1 leads to its reduced binding with the transcription factor SP2, resulting in decreased expression of the downstream gene Idh2. This causes a shift in energy supply toward glycolysis in VSMCs, ultimately contributing to the occurrence and progression of AAA.
Luzheng Zhang, Yu Zhang, Dezhong Wen, Suxiang Guo, Xiaohui Qi, Heng Wang, Yujin Sun, Guangdong Yang, Yuehong Wang, Song Xue   +9 more
wiley   +1 more source

The Lactate Nexus: A Molecular Bridge Linking Physical Activity, Sleep, and Cognitive Enhancement. [PDF]

Biomedicines
Ablitip A, Zheng K, Ding H, Cui Y, Ma X, You Y.   +5 more
europepmc   +1 more source

Comparative Evaluation of Ringer Lactate Infusion of National and Multinational Brand available in Nowshehra, Pakistan

Zawar Hussain, Muhammad Abbas, Saqib Jahan, Abdul Mateen, Ali Khan, Naveed Ahmad, Muhammad Sohail Anwar, Abdul Saboor, Hafiz Sajid Akbar, Rafiullah ., Abdullah ., Wahab Ali, Muhammad Ikram   +12 more
openalex   +2 more sources