Results 261 to 270 of about 985,828 (404)

Histochemical Studies of Fat Metabolism in Mammary Glands of Lactating Cows

, 1954
B. C. Hatziolos, M.L. Yamin-Smith, Joseph Shaw   +2 more
openalex   +1 more source

Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery

Advanced Science, EarlyView.
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou, Xin‐Ge Wang, Xuan‐Ren Shi, Shu‐Ting Sun, Jing Mi, Xiao‐Peng Zhang, Bin‐Cheng Yin, Ying Zhou, Bang‐Ce Ye   +8 more
wiley   +1 more source

Research progress on the interaction between glucose metabolic reprogramming and lactylation in tumors. [PDF]

Front Immunol
Yang Y, Wu Y, Chen H, Xu Z, Lu R, Zhang S, Zhan R, Xi Q, Jin Y.   +8 more
europepmc   +1 more source

Comparison of Alfalfa Fed as Soilage or Silage and the Only Forage for Lactating Dairy Cows

, 1958
C.F. Foreman, R.S. Allen, Arthur R. Porter, P.G. Homeyer   +3 more
openalex   +1 more source

Lactate and pyruvate concentrations in exercised ischemic canine muscle: relationship of tissue substrate level to lactate dehydrogenase isozyme pattern. [PDF]

, 1966
Elliot S. Vesell, P. E. Pool
openalex   +1 more source

Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3‐Regulated HIF1A/HMOX1 Signaling Pathway

Advanced Science, EarlyView.
This study reveals that histone lactylation, a modification derived from lactate, plays a crucial role in ferroptosis resistance in ectopic endometrial stromal cells. This resistance is mediated via the HIF1A/HMOX1 pathway regulated by METTL3. In vivo, a combination of 2‐DG and erastin shows promise as an effective treatment for endometriosis ...
Zongwen Liang, Jinming Liu, Yanling Gou, Honglin Wang, Zhi Li, Yingying Cao, Huiyan Zhang, Ruru Bai, Zongfeng Zhang   +8 more
wiley   +1 more source

Crizotinib: A Novel Strategy to Reverse Immunosuppression in Melanoma by Targeting Lactate Transport. [PDF]

MedComm (2020)
Zhou Z, Zhang X, Zhu S, Liu W, Guo Y, Xiong S, Peng C, Chen X.   +7 more
europepmc   +1 more source

On the Preparation of Ca-lactate from the Still-residue of Biity^|^ucirc;

, 1926
Syoosuke Tanaka
openalex   +2 more sources

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Dynamic Lactate Clearance Patterns During Normothermic Machine Perfusion Predict Posttransplant Biliary Complications in Donation After Circulatory Death Liver Transplantation. [PDF]

Transplant Direct
Obana A, Akabane M, Chi H, Ladd N, Nguyen A, Tan LA, Punjala R, Shah K, Hamilton M, Limkemann A, Singh N, Alebrahim M, Mumtaz K, Schenk A, Black S, Washburn K.   +15 more
europepmc   +1 more source