Results 51 to 60 of about 60,229 (277)
Journal of Medical Science, 2022 Aim. Early discontinuation of metformin before cardiac surgery is advised by several national societies, although no hard evidence exist supporting this practice. This precaution is mostly extrapolated by data on different clinical settings.
Fotini Ampatzidou +3 more
doaj +3 more sources
Minimal lactate clearance proclaims pediatric intensive care unit mortality
Journal of Pediatric Critical Care, 2019 Background: Lactate clearance among the survived patients is higher and is inversely related to the PRISM III Score. Objectives: We aimed to correlate lactate clearance with pediatric Intensive Care Unit (PICU) mortality. Material and Methods: This was
Mushtaq Sheikh +3 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Serum lactate clearance as a predictor of outcome in infants' postcardiac surgery
Heart India, 2022 Background and Aims: Prediction of postoperative outcomes by conventional hemodynamic parameters and risk scoring systems immediately after pediatric cardiac surgery has not been found to be reliable.
Hasmukh Patel +5 more
doaj +1 more source
Reduced gluconeogenesis and lactate clearance in Huntington's disease
Neurobiology of Disease, 2010 We studied systemic and brain glucose and lactate metabolism in Huntington's disease (HD) patients in response to ergometer cycling. Following termination of exercise, blood glucose increased abruptly in control subjects, but no peak was seen in any of the HD patients (2.0 ± 0.5 vs. 0.0 ± 0.2mM, P < 2 × 10(-6)).
Josefsen, Knud +9 more
openaire +4 more sources
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Alcohol consumption decreases lactate clearance in acutely injured patients
, 2016 Introduction—Alcohol, a common risk factor for injury, has direct toxic effects on the liver. The use of lactate clearance has been well described as an indicator of the adequacy of resuscitation in injured patients.
Narayan, M +3 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Frontiers in Cardiovascular Medicine, 2023 ObjectiveThe purpose of this study was to compare the changes in serum lactate between surgical repair and transthoracic device closure of ventricular septal defects (VSDs) in pediatric patients.MethodsThis study was a retrospective analysis, and 314 ...
Jiang-Shan Huang +5 more
doaj +1 more source