Results 31 to 40 of about 223,991 (196)

A Metabolic Change towards Fermentation Drives Cancer Cachexia in Myotubes

Biomedicines, 2021
Cachexia is a disorder associated with several pathologies, including cancer. In this paper, we describe how cachexia is induced in myotubes by a metabolic shift towards fermentation, and the block of this metabolic modification prevents the onset of the
Michele Mannelli, Tania Gamberi, Francesca Magherini, Tania Fiaschi   +3 more
doaj   +1 more source

Cystatin-C is an independent prognostic factor for survival in multiple myeloma and is reduced by bortezomib administration

Haematologica, 2009
Background Renal impairment is a common complication of multiple myeloma. Cystatin-C is considered an accurate marker of glomerular filtration rate in several renal disorders.
Evangelos Terpos, Eirini Katodritou, Evangelos Tsiftsakis, Efstathios Kastritis, Dimitrios Christoulas, Anastasia Pouli, Eurydiki Michalis, Evgenia Verrou, Konstantinos Anargyrou, Konstantinos Tsionos, Meletios A. Dimopoulos, Konstantinos Zervas   +11 more
doaj   +1 more source

Interactions between PPAR Gamma and the Canonical Wnt/Beta-Catenin Pathway in Type 2 Diabetes and Colon Cancer

PPAR Research, 2017
In both colon cancer and type 2 diabetes, metabolic changes induced by upregulation of the Wnt/beta-catenin signaling and downregulation of peroxisome proliferator-activated receptor gamma (PPAR gamma) may help account for the frequent association of ...
Yves Lecarpentier, Victor Claes, Alexandre Vallée, Jean-Louis Hébert   +3 more
doaj   +1 more source

Salivary Lactate Dehydrogenase (LDH) as a Marker for Radiation-induced Mucositis in Head and Neck Cancers: A Preliminary Study [PDF]

Middle East Journal of Cancer, 2019
Background: In this study, we sought to understand the usefulness of salivary lactatedehydrogenase as a predictive marker for the development of radiation-inducedmucositis.Methods: This was a prospective study with head and neck cancer patients ...
Arnadi Shivashankara, Raees Tonse, Sucharitha Suresh, Thomas George, Mamidipudi Vidyasagar, Suresh Rao, Manjeshwar Baliga,   +6 more
doaj   +1 more source

Pattern of hemolysis parameters and association with fetal hemoglobin in sickle cell anemia patients in steady state

Revista Brasileira de Hematologia e Hemoterapia, 2015
Objective: This study aimed to evaluate the influence of fetal hemoglobin (Hb F) on hemolysis biomarkers in sickle cell anemia patients. Methods: Fifty adult sickle cell anemia patients were included in the study.
Juliane Almeida Moreira, Marília Rocha Laurentino, Rosângela Pinheiro Gonçalves Machado, Maritza Cavalcante Barbosa, Ronaldo Pinheiro Gonçalves, Amanda de Menezes Mota, Lilianne Brito da Silva Rocha, Alice Maria Costa Martins, Alcínia Braga de Lima Arruda, Iêda Pereira de Souza, Romélia Pinheiro Gonçalves   +10 more
doaj   +1 more source

BIOMARKERS OF SUBCLINICAL MASTITIS IN THE MAMMARY GLAND OF COWS [PDF]

Biotechnologia Acta, 2017
The aim of the study was to create an algorithm for controlling subclinical forms of mastitis of cows on the basis of determining the activity of lactate dehydrogenase and the number of somatic cells in milk.
V. R. Mazurenko, O. V. Manchulyak
doaj   +1 more source

SUBFRACTIONS OF LACTATE DEHYDROGENASE OF THE RAT [PDF]

Journal of Histochemistry & Cytochemistry, 1966
A survey of the lactate dehydrogenase (LDH) isozymes of 20 organs and tissues of the rat revealed a total of nine fractions exhibiting LDH activity after starch gel electrophoresis. Of the nine LDH fractions, eight were found in testis and lymph node, while the ninth fraction was unique to kidney. The occurrence of LDH fractions in excess of the usual
Janet L. Buta, James L. Conklin, Maynard M. Dewey   +2 more
openaire   +3 more sources

Expression of Lactate Dehydrogenase in Aspergillus niger for L-Lactic Acid Production. [PDF]

PLoS ONE, 2015
Different engineered organisms have been used to produce L-lactate. Poor yields of lactate at low pH and expensive downstream processing remain as bottlenecks.
Khyati K Dave, Narayan S Punekar
doaj   +1 more source

Lactate dehydrogenase supports lactate oxidation in mitochondria isolated from different mouse tissues

Redox Biology, 2020
Research over the past seventy years has established that mitochondrial-l-lactate dehydrogenase (m-L-LDH) is vital for mitochondrial bioenergetics. However, in recent report, Fulghum et al.
Adrian Young, Catherine Oldford, Ryan J. Mailloux   +2 more
doaj   +1 more source

Therapeutic Effect of Curcumin Oral Gel on Salivary Epidermal Growth Factor and Lactate Dehydrogenase Levels in Relation to Oral Mucositis in Head and Neck Cancer Patients Undergoing Concurrent Chemoradiation

Diyala Journal of Medicine
Background: Curcumin is a traditional herbal medication, which has shown promise in a variety of pharmacologic applications. Epidermal growth factor an amino acid polypeptide found in saliva and other bodily fluids, which promotes cell proliferation and
Rouaa S. Farhan, Fawaz D. Al-Aswad
doaj   +1 more source