Results 31 to 40 of about 209,396 (337)
Activity and isozyme content of lactate dehydrogenase under long-term oral taurine administration to rats [PDF]
The Ukrainian Biochemical Journal, 2015 The effect of long-term oral taurine administration to rats on activity of lactate dehydrogenase (LDH), its isozyme content and activity in the whole blood, liver, thigh muscle, brain and testes tissues were studied in the present work.
R. D. Ostapiv +2 more
doaj +1 more source
Using machine learning techniques to predict hospital admission at the emergency department [PDF]
arXiv, 2021 Introduction: One of the most important tasks in the Emergency Department (ED) is to promptly identify the patients who will benefit from hospital admission. Machine Learning (ML) techniques show promise as diagnostic aids in healthcare. Material and methods: We investigated the following features seeking to investigate their performance in predicting ...
arxiv
Characterization of Rabbit Lactate Dehydrogenase-M and Lactate Dehydrogenase-H cDNAs
Journal of Biological Chemistry, 1989 Two cDNA clones were isolated, one corresponding to the mRNA coding for lactate dehydrogenase-M (LDH-M), the other to the mRNA coding for lactate dehydrogenase-H (LDH-H). The cDNA inserts consist of the entire open reading frame for LDH-M and a partial sequence, from amino acid 117 to 332, for LDH-H. Using these two clones as probes we demonstrate that:
M Renaud +4 more
openaire +3 more sources
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
Estimation of lactate threshold with machine learning techniques in recreational runners [PDF]
Applied Soft Computing, 63, 181-196 (2018), 2018 Lactate threshold is considered an essential parameter when assessing performance of elite and recreational runners and prescribing training intensities in endurance sports. However, the measurement of blood lactate concentration requires expensive equipment and the extraction of blood samples, which are inconvenient for frequent monitoring ...
arxiv +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
BIO-CXRNET: A Robust Multimodal Stacking Machine Learning Technique for Mortality Risk Prediction of COVID-19 Patients using Chest X-Ray Images and Clinical Data [PDF]
arXiv, 2022 Fast and accurate detection of the disease can significantly help in reducing the strain on the healthcare facility of any country to reduce the mortality during any pandemic. The goal of this work is to create a multimodal system using a novel machine learning framework that uses both Chest X-ray (CXR) images and clinical data to predict severity in ...
arxiv
Characterization of apparent lactate dehydrogenase isoenzyme 6: a lactate-independent dehydrogenase.
Clinical Chemistry, 1984 Abstract We found in a prospective study of lactate dehydrogenase isoenzyme 6 (LD6) in human tissues obtained at autopsy that LD6 was usually present in liver when death was preceded by prolonged hypotension or impaired ventilation but not in cases of sudden death. Other organs containing LD6 were kidney and spleen.
R A McPherson +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Lactate Dehydrogenase Isoenzymes
Clinical Chemistry, 1967 Abstract Five lactate dehydrogenase isoenzymes are normally observed in human serum: H4 (LDH1), H3M (LDH2), H2M2 (LDH3), HM3 (LDH4), and M4 (LDH5). This study presents evidence that these isoenzymes vary in the ratio of LDH activity (pyruvate → lactate) to LDH activity (lactate → pyruvate).
John Bernard Henry +2 more
openaire +3 more sources