Results 31 to 40 of about 471,023 (292)

Comparison of different criteria for the diagnosis of primary myelofibrosis reveals limited clinical utility for measurement of serum lactate dehydrogenase

Haematologica, 2010
Primary myelofibrosis shows histological and pathogenetic overlap with essential thrombocythemia and polycythemia vera. Several diagnostic classifications have been proposed for primary myelofibrosis, although little is known about their clinical utility.
Philip A. Beer, Peter J. Campbell, Anthony R. Green   +2 more
doaj   +1 more source

The D-Lactate Dehydrogenase from Sporolactobacillus inulinus Also Possessing Reversible Deamination Activity. [PDF]

PLoS ONE, 2015
Hydroxyacid dehydrogenases are responsible for the conversion of 2-keto acids to 2-hydroxyacids and have a wide range of biotechnological applications.
Lingfeng Zhu, Xiaoling Xu, Limin Wang, Hui Dong, Bo Yu   +4 more
doaj   +1 more source

Biosensors based on electrochemical lactate detection: A comprehensive review

Biochemistry and Biophysics Reports, 2016
Lactate detection plays a significant role in healthcare, food industries and is specially necessitated in conditions like hemorrhage, respiratory failure, hepatic disease, sepsis and tissue hypoxia. Conventional methods for lactate determination are not
Kavita Rathee, Vikas Dhull, Rekha Dhull, Sandeep Singh   +3 more
doaj   +1 more source

LACTATE DEHYDROGENASE : EFFECT OF AMINO ACID CHANGES ON PROPERTIES [PDF]

, 2023
Many changes have been made by protein engineering in lactate dehydrogenase from B.stearothermophilus. The role of groups involved in susbtrate and coenzyme binding, catalysis and effector molecule binding has been deduced and variants with improved ...
Wigley, D. B., Holbrook, J. J., Nicholls, D. J., Clarke, A. R., Barstow, D. A., Chia, W. N., Atkinson, T., Scawen, M. D., Hart, K. W.   +8 more
core   +1 more source

A STUDY OF SERUM LACTATE AS A PREDICTOR OF SEVERITY IN DENGUE INFECTION

National Journal of Medical Research, 2023
Background: Dengue infections caused by the four antigenically distinct dengue virus serotypes (DENV1, DENV2, DENV3, DENV4) of the family Flaviviridae are the most major arboviral diseases in humans in terms of geographic spread, morbidity, and ...
Meet Ladani, Deepak Shukla, Rakesh Raval, Tejas Goyani, Srushti Vadodaria   +4 more
doaj   +1 more source

Induction of alcohol dehydrogenase and lactate dehydrogenase in hypoxically induced barley

, 1989
In barley (Hordeum vulgare L.), alcohol dehydrogenase (ADH) and lactate dehydrogenase (LDH) are induced by anaerobiosis in both aleurone layers and roots.
Good, A. G., Crosby, W. L.
core   +1 more source

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho, Emmanuella Amoako, Nihad Salifu, Lily Gloria Tagoe, Yaw Bediako, Michelle Hermiston, Catherine Segbefia   +6 more
wiley   +1 more source

Lactate-proton co-transport and its contribution to interstitial acidification during hypoxia in isolated rat spinal roots [PDF]

, 1993
Exposure of nervous tissue to hypoxia results in interstitial acidification. There is evidence for concomitant decrease in extracellular pH to the increase in tissue lactate.
Schneider, Uwe, Poole, RC, Halestrap, Andrew P., Grafe, Peter, Grafe, P, Poole, Robert C., Schneider, U, Halestrap, AP   +7 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Lactate Dehydrogenases of Hemopoietic Cells [PDF]

Blood, 1966
Abstract In summary we have demonstrated that hemopoietic stem cells of man contain all five isoenzymes, and not a single pure type. Our data and the results of others obtained from fetal tissue also indicate that embryonic LDH of man exists as multiple forms.
W H, Starkweather, H H, Spencer, H K, Schoch   +2 more
openaire   +2 more sources