The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Estimation of lactate threshold with machine learning techniques in recreational runners [PDF]
Applied Soft Computing, 63, 181-196 (2018), 2018 Lactate threshold is considered an essential parameter when assessing performance of elite and recreational runners and prescribing training intensities in endurance sports. However, the measurement of blood lactate concentration requires expensive equipment and the extraction of blood samples, which are inconvenient for frequent monitoring ...
arxiv +1 more source
Stabilization of lactate dehydrogenase [PDF]
, 1972 Addition of substances such as dimethylsulfoxide, glycerol, and gelatin to aqueous solutions of lactate dehydrogenase maintains enzymes in stable and fully active form when stored at 2 - 6 ...
Friedman, O. M.
core +1 more source
Formate Excretion in Urine of Rats Fed Dimethylaminoazobenzene-rich Diets: The Possibility of Formate Formation from D-Lactate [PDF]
, 2008 This experiment was carried out to evaluate the possibility of degradation of d-lactate into formate and acetaldehyde. In order to induce hyperproduction of d-lactate in rats.
Kawase, Michi +2 more
core +1 more source
Lactate dehydrogenase activity drives hair follicle stem cell activation
Nature Cell Biology, 2017 Although normally dormant, hair follicle stem cells (HFSCs) quickly become activated to divide during a new hair cycle. The quiescence of HFSCs is known to be regulated by a number of intrinsic and extrinsic mechanisms.
A. Flores +16 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez +3 more
wiley +1 more source
BIO-CXRNET: A Robust Multimodal Stacking Machine Learning Technique for Mortality Risk Prediction of COVID-19 Patients using Chest X-Ray Images and Clinical Data [PDF]
arXiv, 2022 Fast and accurate detection of the disease can significantly help in reducing the strain on the healthcare facility of any country to reduce the mortality during any pandemic. The goal of this work is to create a multimodal system using a novel machine learning framework that uses both Chest X-ray (CXR) images and clinical data to predict severity in ...
arxiv
Latent acetylcholinesterase in secretory vesicles isolated from adrenal medulla [PDF]
, 1981 A new procedure is described for the preparation of highly purified and stable secretory vesicles from adrenal medulla. Two forms of acetylcholinesterase, a membrane bound form as well as a soluble form, were found within these vesicles.
Abbs +38 more
core +1 more source
Characterization of apparent lactate dehydrogenase isoenzyme 6: a lactate-independent dehydrogenase.
Clinical Chemistry, 1984 Abstract We found in a prospective study of lactate dehydrogenase isoenzyme 6 (LD6) in human tissues obtained at autopsy that LD6 was usually present in liver when death was preceded by prolonged hypotension or impaired ventilation but not in cases of sudden death. Other organs containing LD6 were kidney and spleen.
R A McPherson +2 more
openaire +3 more sources
Inhibition of lactate dehydrogenase A suppresses inflammatory response in RAW 264.7 macrophages.
Molecular Medicine Reports, 2018 Lactate is an important metabolite in cellular metabolism and fluctuates in certain disease conditions including cancer and immune diseases.
Yoo-Jeong Song +8 more
semanticscholar +1 more source