Results 101 to 110 of about 2,083,504 (286)

Relationships between symptoms and changes in breast physiology during lactation mastitis [PDF]

open access: yes, 2006
OBJECTIVE: The objective was to investigate changes in milk composition that reflect variations in breast permeability, milk synthesis, and immune response in women before, during, and after mastitis. METHODS: Mothers (n = 26) were followed prospectively
Fetherston, C.M.   +2 more
core  

Food resource allocation patterns in lactating females in a long-term selection experiment for litter size in mice [PDF]

open access: yes, 2002
Resource allocation patterns, as quantified by residual food intake (RFI), and the consequences for offspring development were investigated during lactation in 96 females of a mouse line selected for 104 generations for high litter size at birth (S-line)
Luiting, Petronella   +18 more
core   +1 more source

Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy

open access: yesAdvanced Science, EarlyView.
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang   +5 more
wiley   +1 more source

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

open access: yesAdvanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang   +12 more
wiley   +1 more source

RGS16 Aggravates Hepatic Ischemia‐Reperfusion Injury via Hepatocyte‐Intrinsic Apoptosis/Inflammation & Neutrophil Recruitment/NETosis

open access: yesAdvanced Science, EarlyView.
RGS16 competitively interferes with the YTHDF3–PAN3 complex to prevent CXCL1 mRNA decay during hepatic ischemia‐reperfusion injury. Stabilized CXCL1 strengthens hepatocyte injury, neutrophil recruitment, and NET‐associated inflammation, uncovering how stress‐induced RGS16 converts post‐transcriptional regulation into immune‐mediated liver damage ...
Xinglong Li   +16 more
wiley   +1 more source

Fitting lactation curves in a Colombian Holstein herd using nonlinear models

open access: yesRevista Facultad Nacional de Agronomía Medellín, 2018
Statistical characterization of dairy cows lactation curves allows prediction of total milk yield from one or a few test-day records. The objectives were the characterization of milk production in a Colombian Holstein herd under tropical dairy production
Norma Patricia Duque López   +4 more
doaj   +1 more source

[Length of lactational amenorrhea in an urban population of Temuco, Chile].

open access: yesRevista medica de Chile, 2002
Studies done in Santiago, Chile show that menses return before the sixth month of puerperium in 50% of lactating women, even in those that continue with exclusive breast feeding.To study the length of lactational amenorrhea in a group of women living in Southern Chile.One hundred fourteen women giving exclusive breast feeding, were followed from the ...
Patricio, Valdés   +3 more
openaire   +1 more source

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

open access: yesAdvanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma   +14 more
wiley   +1 more source

Genetic Relationship of Body Energy and Blood Metabolites with Reproduction in Holstein Cows [PDF]

open access: yes, 2008
Body condition score (BCS), energy content (EC), cumulative effective energy balance (CEEB), and blood serum concentrations of glucose, beta-hydroxybutyrate (BHBA), and nonesterified fatty acids ( NEFA) were measured throughout first lactation in 497 ...
Arsenos, G.   +5 more
core   +1 more source

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