Results 121 to 130 of about 2,083,504 (286)

A Novel tRNA Half mt‐5’‐tiRNA‐Tyr Promotes Colorectal Cancer Proliferation via Inducing HARS2 Succinylation

Advanced Science, EarlyView.
A mitochondria‐derived tRNA half, mt‐5’‐tiRNA‐Tyr, is upregulated in colorectal cancer tissues and plasma and promotes tumor proliferation. It binds HARS2 and promotes CPT1A‐associated HARS2 K91 succinylation, disrupts HARS2–mt‐tRNA‐His association, impairs mitochondrial translation, enhances succinate‐linked metabolic reprogramming, and shows promise ...
Xinliang Gu, Danping Zhu, Xinwei Liu, Shangshang Hu, Xincheng Yang, Junjie Nie, Tao Xu, Yuqin Pan, Mu Xu, Huiling Sun, Shukui Wang   +10 more
wiley   +1 more source

Production Parameters in a Romanian Buffalo Population

Scientific Papers Animal Science and Biotechnologies, 2023
The biological material of buffaloes in this area shows favorable characteristics in the direction of milk production with a total length of lactation almost close to the normal one, but the interval between births is quite high. Pure milk fat content on
Aurelia Coroian, Vioara Mireșan, Cristian O. Coroian, Iulia Feștilă, Daniel Cocan, Camelia Răducu, Stelian Dărăban   +6 more
doaj  

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

Advanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao, Wei Gu, Yimin Ren, Chenfei Lu, Wanzhi Cai, Junnan Lu, Zhongyuan Bao, Yanan Zhou, Rong Li, Ke Jin, Chao Chen, Hongxiang Wang, Lei Xu, Juxiang Chen   +13 more
wiley   +1 more source

Nutritional supplements during breastfeeding [PDF]

, 2011
Women who are breastfeeding have increased requirements for energy and nutrients. Nutritional requirements for lactation have been the subject of several international reports and are included in general nutrient requirements documents, including those ...
Binns, C.W., Scott, J., Lee, M., Zhao, Yun, Oddy, W., Lee, M.K., Zhao, Y., Binns, Colin   +7 more
core  

Plasma and Milk Variables Classify Diet, Dry Period Length, and Lactation Week of Dairy Cows Using a Machine Learning Approach

Metabolites
Background/Objectives: The aim of this study was to classify cows with respect to different diets, dry period (DP) lengths, and lactation weeks based on body weight, milk variables, and plasma metabolites measured in early lactation.
Xiaodan Wang, Sanjeevan Jahagirdar, Bas Kemp, Josef J. Gross, Rupert M. Bruckmaier, Edoardo Saccenti, Ariette van Knegsel   +6 more
doaj   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li, Yong Wei, Yongshan Li, Yuxiang Dong, Jiancheng Lv, Mingzhi Yuan, Ao Shen, Fuyang Liu, Yetao Zhang, Youjian Li, Ruixi Yu, Yang Liu, Tong Zhao, Jun Wang, Kai Zhou, Zongyao Fan, Manning Wang, Jun Xu, Mulong Du, Min Gu, Bing Yao, Qingyi Zhu   +21 more
wiley   +1 more source

ACCURACY OF MILK YIELD ESTIMATION IN DAIRY CATTLE FROM MONTHLY RECORD BY REGRESSION METHOD [PDF]

, 2009
This experiment was conducted to estimate the actual milk yield and to compare the estimation accuracy of cumulative monthly record to actual milk yield by regression method.
Kurnianto, E. (E), Nuringtias, N. L. (N), Johari, S, Kuswahyuni, I S, Kurnianto, E, Nuringtias, N L, Johari, S. (S), Kuswahyuni, I. S. (I)   +7 more
core   +1 more source

MetaboSense: An Integrated Quantum Dot‐Mediated Aptamer Assay and Modular Microfluidic Platform for Continuous In‐Line Monitoring of Lung Metabolism During Ex Vivo Perfusion

Advanced Science, EarlyView.
MetaboSense is a first‐of‐its‐kind microfluidic platform enabling continuous, in‐line monitoring of glucose and lactate during ex vivo lung perfusion. Combining a quantum dot–mediated aptamer assay with mixing, depletion, and optofluidic detection modules, it achieves 60–s temporal resolution and shows strong agreement with standard blood gas analyzers,
Sanjana Srikant, Pouyan Keshavarz Motamed, Thomas Borrillo, Lielle Ronen, Gabriel Siebiger, Guillermo Garza, Hesam Abouali, Md Fahim Al Fattah, Ines Jaber, Dayan Ban, Marcelo Cypel, Mingyao Liu, Shaf Keshavjee, Andrew T. Sage, Mahla Poudineh   +14 more
wiley   +1 more source

Genetic aspects of feed intake in lactating sows [PDF]

, 2011
Productivity of sows has increased worldwide, especially during the last decade. Sows have been changed genetically to produce larger litters. It was hypothesized that including feed intake or feed efficiency during lactation or both in the breeding ...
Bergsma, R.
core