Results 101 to 110 of about 215,605 (258)
Fenestrated Microneedle Biosensor for Continuous In Vivo Lactate Monitoring in Interstitial Fluid
Small, EarlyView.A fenestrated microneedle biosensor enables continuous transdermal monitoring of lactate in interstitial fluid while protecting the functional sensing interface during insertion into the skin. The platform delivers sensitive electrochemical lactate detection and distinguishes metabolic profiles in healthy and type 2 diabetic‐obese mice, and captures ...
Masoud Khazaei +5 more
wiley +1 more source
Case Reports in Immunology, 2018 Type B lactic acidosis is a rare metabolic complication sometimes associated with hematologic malignancies. When present, this type of lactic acidosis is most commonly seen in patients with high-grade lymphomas or leukemias and is usually indicative of a
Marco Mejia +6 more
doaj +1 more source
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.The Swedish fetal heart rate (FHR) classification from 2017 identifies most FHR patterns associated with fetal acidemia as non‐normal, according to fetal blood sampling (FBS) in immediate connection to the ongoing FHR pattern. However, long‐standing FHR patterns with non‐repetitive decelerations of the types severe variable and late warrant increased ...
Erika Gyllencreutz +4 more
wiley +1 more source
Clinical manifestations of dual‐gene variants in retinitis pigmentosa
Acta Ophthalmologica, EarlyView.Abstract Purpose Retinitis pigmentosa (RP) is an inherited retinal disease (IRD), whereby each affected individual typically harbours pathogenic variants in a single causative gene, yet the disorder exhibits marked genetic heterogeneity, with more than 100 genes reported to underlie RP.
Lasse Wolfram +11 more
wiley +1 more source
International Journal of Endocrinology, 2014 Objective. To clarify the link between metformin accumulation and its metabolic consequences by taking the time frame for metformin measurement into account. Research Design and Methods.
Jean-Daniel Lalau, Farshad Kajbaf
doaj +1 more source
Non‐Alzheimer Aβ deposits in the human CNS: Implications with hypoxia and related conditions
Brain Pathology, EarlyView.An Aβ deposit in a non‐Alzheimer's brain from an individual who experienced hypoxia/energy failure. Abstract We recently reported the deposition of Aβ in the frontal cortex of individuals who died of acute coronavirus disease 2019 (COVID‐19), or who did not have COVID‐19 but had respiratory distress, or infants with severe cardiac malformations.
Esma Karlovich +5 more
wiley +1 more source
Metformin and Lactic Acidosis in Diabetic Patients
, 2021 Metformin is the basic drug in the clinical treatment of Diabetes, often used in the treatment of Type 2 Diabetes Mellitus (T2DM).Its effect has been fully verified in the clinical treatment of T2DM.
Yu, Yiying +6 more
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Expanding the Biochemical Phenotype of ReNU Syndrome: A Case Report
Clinical Genetics, EarlyView.This report detailed the clinical findings and the biochemical phenotype of a 3‐year‐old girl with ReNU syndrome. Circulating biomarkers and a muscle biopsy s uggested mild mitochondrial abnormalities. Severe plasmalogen deficiency was also observed, comparable to defects of peroxisomal plasmalogen biosynthesis.
Irene De Biase +4 more
wiley +1 more source
Modulation of sebocyte function in acne: A pathway‐inclusive review
Journal of the European Academy of Dermatology and Venereology, EarlyView.Acne is multifactorial, with the sebocyte acting as a central immunometabolic hub linking lipogenic, inflammatory, hormonal and barrier pathways. Mapping established and investigational therapies onto this sebocyte‐centred model offers a mechanism‐based framework that complements existing treatment paradigms and may guide more targeted, antibiotic ...
Christos C. Zouboulis +3 more
wiley +1 more source