Results 121 to 130 of about 65,237 (244)

Unusual Case of Severe Lactic Acidosis in a Liver Transplant Patient

Case Reports in Transplantation, 2017
Lactic acidosis is a standard indicator for oxygen debt and some other very significant causes. We describe a case of liver transplant patient presenting with vague abdominal pain and lactic acidosis without any liver dysfunction/failure/ischemia ...
Shweta Yemul Golhar, Michael S. Green, Stephen Guy   +2 more
doaj   +1 more source

Effect of Two Therapeutic Renal Diets on Hormonal and Regulatory Pathways Affecting Calcium Homeostasis in Cats With Early‐Stage Chronic Kidney Disease

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is a known risk factor for hypercalcemia in cats. Phosphate‐restricted diets have also been implicated in causing hypercalcemia, in part because phosphate restriction increases the Ca:P ratio. The primary objective of this study was to evaluate the impact of two different therapeutic renal foods on ionized (iCa ...
Jean A. Hall, Elizabeth M. Morris, Dale A. Fritsch, John J. Brejda, Kim M. Wilson   +4 more
wiley   +1 more source

in vitro activation of complement and contact system by lactic acidosis

Mediators of Inflammation, 1998
The activation of complement and contact systems occurs in reperfusion injuries with initial tissue hypoxia, and lactic acidosis such as mycardial infarction and birth asphyxia.
J. Sonntag, M. Emeis, E. Strauss, M. Obladen   +3 more
doaj   +1 more source

Status Epilepticus After Electrocution Injury in a Dog

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To describe a case of status epilepticus secondary to electrocution injury associated with an electric fence. Case Summary A 1.5‐year‐old male Kangal Shepherd Dog mix was presented to the emergency service after being entangled in an agricultural electric fence for 1–2 h. On presentation, the dog was recumbent, was unable to stand or
Julia Ortlieb, Sofie Muthmann, Fabienne Blunschi, Adriana Czerwik, Agnieszka Olszewska, Esther Hassdenteufel   +5 more
wiley   +1 more source

Hypoxic‐hypocapnic red blood cells in PAGGSM additive solution before and after gamma irradiation show improved metabolism

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Hypoxic/hypocapnic (HH) treatment and storage conditions have been shown to reduce oxidative stress and improve red blood cell (RBC) quality. This study aimed to validate a good manufacturing practice HH RBC product for obtaining the licence for routine use in patients, by comparison with normoxic RBCs both without ...
Soroth Chey, Jacqueline Maier, Samuel Sowemimo‐Coker, Reinhard Henschler   +3 more
wiley   +1 more source

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

The Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich, Ulas Ozkurede, Shanmugasundaram Pakkiriswami, Ryan Gemilere, Samira M. Azarin, Julia C. Liu   +5 more
wiley   +1 more source

Skeletal muscle adaptation to muscle activity and hypoxia: Differential structural and metabolic remodelling

The Journal of Physiology, EarlyView.
Abstract figure legend There has been controversy about the structural (capillary) response of skeletal muscle to altered O2 status, involving decreased supply (hypoxia) or increased demand (activity). Here we demonstrate that seven days of activation of skeletal muscle by indirect electrical stimulation led to significant expansion of the capillary ...
David Hauton, Roger W.P. Kissane, James McCullagh, Stuart Egginton   +3 more
wiley   +1 more source

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini, Hassan Valadbeigi, Seyedeh Mahdieh Khoshnazar, Saeed Khoshnood, Shahab Falahi, Delsuz Rezaee, Ali Hematian, Mohammad Hossein Haddadi   +7 more
wiley   +1 more source

BMQ [PDF]

, 1958
BMQ: Boston Medical Quarterly was published from 1950-1966 by the Boston University School of Medicine and the Massachusetts Memorial ...
Bakst, Henry J., Berry, Joseph, Bonnet, Philip D., Bradford, Martin L., Curran, William J., Emerson, Charles P., Greer, William E. R., Huckabee, William E., Hutt, Michael S. R., Keefer, Chester S., Laforet, Eugene G., Lemon, Henry M., O'Brien, Gerald F., Relman, Arnold S., Soutter, Lamar, Street, Russell B., Jr., Waye, Jerome D.   +16 more
core  

Severe, Non‐apneic Respiratory Dysfunction and Hypoxia following Generalized Convulsive Seizures

Annals of Neurology, Volume 99, Issue 5, Page 1263-1276, May 2026.
Objective Sudden unexpected death in epilepsy (SUDEP) is a devastating consequence of some generalized convulsive seizures (GCS). Recent work has focused on seizure related apnea as a biomarker of SUDEP risk, frequently without characterizing the adequacy of non‐apneic ventilation or identifying other dysfunctional breathing patterns.
Haley E. Pysick, Rup K. Sainju, Roshni Nair, Deidre N. Dragon, Eduardo Bravo, Laura Vilella, Xiaojin Li, Samden D. Lhatoo, George B. Richerson, Brian K. Gehlbach   +9 more
wiley   +1 more source