Results 131 to 140 of about 65,237 (244)
Turkish Journal of Nephrology, 2019 Metformin is a biguanide used in the treatment of type 2 diabetic patients with normal renal function. Lactic acidosis is the most serious side effect of metformin. Renal failure is the most common cause of reduced lactate excretion.
Mustafa YAPRAK +7 more
doaj
Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.ABSTRACT Riboflavin (RF, vitamin B2) is an essential vitamin of which the co‐factors are critical to numerous cellular processes. RF is used as a treatment for inherited metabolic diseases (IMDs), although its effectiveness in many disorders has not been established.
Bregje Jaeger +7 more
wiley +1 more source
Journal of Pediatric Critical CareDiabetic ketoacidosis (DKA) is a life-threatening complication of diabetes mellitus, characterized by hyperglycemia, ketosis, and metabolic acidosis. Severe dehydration and hypovolemic shock in severe DKA are common, but myocardial dysfunction and lactic
Sannarudrappa Sagar +3 more
doaj +1 more source
Antenatal Presentation of MRPS22‐Related Mitochondrial Disease Confirmed With Rapid Proteomics
JIMD Reports, Volume 67, Issue 3, May 2026.ABSTRACT MRPS22‐related mitochondrial disease (MIM#611719) is a rare autosomal recessive disorder caused by defects in the mitochondrial ribosomal protein S22, a component of the small mitoribosomal subunit essential for mitochondrial translation. Of the few reported cases, most present antenatally with a severe phenotype, conveying a poor prognosis ...
Liana N. Semcesen +43 more
wiley +1 more source
Determining predictors of underlying etiology and clinical deterioration in patients with physiologic instability in the emergency department [PDF]
, 2013 Thesis (M.A.)--Boston UniversityShock is a critical state defined by inadequate oxygen delivery to tissues. It is well known in the critical care community that early diagnosis and treatment of shock are crucial to improving patient outcomes. However, in
Day, Danielle E.
core +1 more source
The Dairy Ruminant Gut Microbiome: Profile, Responsiveness to Seasonality and Impact on Milk Quality
Environmental Microbiology, Volume 28, Issue 5, May 2026.The dairy ruminant gut microbiome that is shaped by host and diet is affected by seasonality and rearing. These factors can impact dairy productivity and milk quality potentially through the gut microbiota. ABSTRACT The gut microbiome (GM) and particularly the rumen microbiome (RM) affect the ruminant health and they are associated with milk quality ...
Alexandra Ntemiri +2 more
wiley +1 more source
Clinical Physiology and Functional Imaging, Volume 46, Issue 3, May 2026.Abstract This study evaluates mannitol as a clearance marker for measuring glomerular filtration rate (GFR) in outpatients with chronic kidney disease (CKD). Multi‐sample iohexol clearance served as the reference method. Twenty patients with CKD, stages 3–4, received bolus injections of both clearance markers simultaneously.
Katalin Kiss +3 more
wiley +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4112-4120, May 2026.ABSTRACT Aims Evogliptin, a dipeptidyl peptidase‐4 inhibitor with a glucose‐dependent mechanism of action, is widely used as a monotherapy or in combination with other agents. However, observational studies in routine clinical settings remain limited.
Jun Hwa Hong +14 more
wiley +1 more source