Results 121 to 130 of about 140,146 (333)

Identification of Massoia Lactone and its Hydroxy-derivative from Kabatiella caulivora, an Endophyte of the Terrestrial Plant Alyxia reinwardtii

open access: yesMakara Journal of Science, 2017
Massoia lactone (1) and its derivative, 3,5-dihydroxydecanoic acid-d-lactone (2), were identified from an ethyl acetate extract of the endophytic fungus Kabatiella caulivora, isolated from its host Alyxia reinwardtii.
Izzatul Laili   +4 more
doaj   +1 more source

Deconjugation Kinetics of Glucuronidated Phase II Flavonoid Metabolites by B-glucuronidase from Neutrophils [PDF]

open access: yes, 2010
Flavonoids are inactivated by phase II metabolism and occur in the body as glucuronides. Mammalian ß-glucuronidase released from neutrophils at inflammatory sites may be able to deconjugate and thus activate flavonoid glucuronides.
Arts, I.C.W.   +9 more
core   +2 more sources

The Synthesis of Cyclopropyl‐Fused Tetrahydrofurans from Vinylcyclopropanes

open access: yesAsian Journal of Organic Chemistry, EarlyView.
Vinylcyclopropanes undergo iodocyclization to afford a series of oxabicyclo[3.1.0]hexanols. These substrates were shown to be useful intermediates for the construction of various cyclopropyl‐fused polycycles. Abstract The rapid synthesis of oxabicyclo[3.1.0]hexanols from various vinylcyclopropanes is described.
Alexander J. Craig   +7 more
wiley   +1 more source

A C‐to‐B Atom Swap on Coumarins and Dibenzolactones

open access: yesAngewandte Chemie, EarlyView.
Cyclic boronic hemiesters, boron isosteres of lactones, display unique and valuable chemical properties. Herein, we report a novel method for their synthesis via nickel‐catalyzed decarbonylative borylation, enabled by electron‐rich phosphine ligands to achieve a formal “C‐to‐B” atom swap.
Tian You, Quang H. Luu, Junqi Li
wiley   +2 more sources

New approach to the equilibrium of D-glucaric acid in water: DFT study of tetrahedral intermediates

open access: yesKuwait Journal of Science
The present study aims at investigating, for the first time, the formation of tetrahedral intermediates during the equilibrium mechanism of D-glucaric acid in water.
Amara S.
doaj   +1 more source

Unusual Multiple Production of N-Acylhomoserine Lactones a by Burkholderia sp. Strain C10B Isolated from Dentine Caries

open access: yesSensors, 2014
Bacteria realize the ability to communicate by production of quorum sensing (QS) molecules called autoinducers, which regulate the physiological activities in their ecological niches.
Share Yuan Goh   +6 more
doaj   +1 more source

Parthenolide eliminates leukemia-initiating cell populations and improves survival in xenografts of childhood acute lymphoblastic leukemia [PDF]

open access: yes, 2013
Key Points First report demonstrating in vivo elimination of multiple LIC populations from childhood ALL cases using animal models. In vivo models of leukemia are essential for drug evaluation studies.
Blair, Allison   +3 more
core   +1 more source

A hepatoprotective experiment on taro vegetable (Colocasia esculenta (L.) Schott) flower employing animal models by mitigating oxidative stress

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The antioxidant efficacy of Colocasia esculenta flower’s methanolic extract was assessed using 2,2′‐azino‐bis‐(3‐ethylbenzothiazoline‐6‐sulfonic) (ABTS) and 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) scavenging assay. The hepatoprotective effect was investigated by assessing liver injury indicators (amino transferase [ALT], aspartate amino transferase [AST],
Mahathir Mohammad   +9 more
wiley   +1 more source

Deciphering Tryptophan Oxygenation: Key Modulators of 2‐Oxindole Formation in MarE

open access: yesAngewandte Chemie, EarlyView.
This study reveals that MarE, a heme‐dependent aromatic oxygenase, favors dioxygenation of β‐methyl‐l‐tryptophan in the absence of ascorbate and demonstrates how structural and redox tuning shifts its reactivity toward selective monooxygenation, yielding a 2‐oxindole scaffold. These findings offer new insights into enzyme‐controlled indole oxidation in
Romie C. Nguyen, Inchul Shin, Aimin Liu
wiley   +2 more sources

Dependence of copolymer sequencing based on lactone ring size and ε-substitution [PDF]

open access: yes, 2016
The copolymerization of an ε-substituted ε-lactone, menthide (MI), and a range of nonsubstituted lactones (6-, 7-, 8-, and 9-membered rings) was investigated in order to determine the factors that affect the sequencing of the MI copolymers.
Dove, Andrew P.   +3 more
core   +2 more sources

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