Results 121 to 130 of about 140,146 (333)
Massoia lactone (1) and its derivative, 3,5-dihydroxydecanoic acid-d-lactone (2), were identified from an ethyl acetate extract of the endophytic fungus Kabatiella caulivora, isolated from its host Alyxia reinwardtii.
Izzatul Laili+4 more
doaj +1 more source
Deconjugation Kinetics of Glucuronidated Phase II Flavonoid Metabolites by B-glucuronidase from Neutrophils [PDF]
Flavonoids are inactivated by phase II metabolism and occur in the body as glucuronides. Mammalian ß-glucuronidase released from neutrophils at inflammatory sites may be able to deconjugate and thus activate flavonoid glucuronides.
Arts, I.C.W.+9 more
core +2 more sources
The Synthesis of Cyclopropyl‐Fused Tetrahydrofurans from Vinylcyclopropanes
Vinylcyclopropanes undergo iodocyclization to afford a series of oxabicyclo[3.1.0]hexanols. These substrates were shown to be useful intermediates for the construction of various cyclopropyl‐fused polycycles. Abstract The rapid synthesis of oxabicyclo[3.1.0]hexanols from various vinylcyclopropanes is described.
Alexander J. Craig+7 more
wiley +1 more source
A C‐to‐B Atom Swap on Coumarins and Dibenzolactones
Cyclic boronic hemiesters, boron isosteres of lactones, display unique and valuable chemical properties. Herein, we report a novel method for their synthesis via nickel‐catalyzed decarbonylative borylation, enabled by electron‐rich phosphine ligands to achieve a formal “C‐to‐B” atom swap.
Tian You, Quang H. Luu, Junqi Li
wiley +2 more sources
New approach to the equilibrium of D-glucaric acid in water: DFT study of tetrahedral intermediates
The present study aims at investigating, for the first time, the formation of tetrahedral intermediates during the equilibrium mechanism of D-glucaric acid in water.
Amara S.
doaj +1 more source
Bacteria realize the ability to communicate by production of quorum sensing (QS) molecules called autoinducers, which regulate the physiological activities in their ecological niches.
Share Yuan Goh+6 more
doaj +1 more source
Parthenolide eliminates leukemia-initiating cell populations and improves survival in xenografts of childhood acute lymphoblastic leukemia [PDF]
Key Points First report demonstrating in vivo elimination of multiple LIC populations from childhood ALL cases using animal models. In vivo models of leukemia are essential for drug evaluation studies.
Blair, Allison+3 more
core +1 more source
The antioxidant efficacy of Colocasia esculenta flower’s methanolic extract was assessed using 2,2′‐azino‐bis‐(3‐ethylbenzothiazoline‐6‐sulfonic) (ABTS) and 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) scavenging assay. The hepatoprotective effect was investigated by assessing liver injury indicators (amino transferase [ALT], aspartate amino transferase [AST],
Mahathir Mohammad+9 more
wiley +1 more source
Deciphering Tryptophan Oxygenation: Key Modulators of 2‐Oxindole Formation in MarE
This study reveals that MarE, a heme‐dependent aromatic oxygenase, favors dioxygenation of β‐methyl‐l‐tryptophan in the absence of ascorbate and demonstrates how structural and redox tuning shifts its reactivity toward selective monooxygenation, yielding a 2‐oxindole scaffold. These findings offer new insights into enzyme‐controlled indole oxidation in
Romie C. Nguyen, Inchul Shin, Aimin Liu
wiley +2 more sources
Dependence of copolymer sequencing based on lactone ring size and ε-substitution [PDF]
The copolymerization of an ε-substituted ε-lactone, menthide (MI), and a range of nonsubstituted lactones (6-, 7-, 8-, and 9-membered rings) was investigated in order to determine the factors that affect the sequencing of the MI copolymers.
Dove, Andrew P.+3 more
core +2 more sources