Results 151 to 160 of about 140,146 (333)

The Chemistry and Biology of the Tetrodotoxin Natural Product Family

open access: yesAngewandte Chemie International Edition, EarlyView.
Tetrodotoxin is best known as the poison of the pufferfish, which is a delicacy in Japanese cuisine. Its toxicity arises from the selective blockage of NaV channels, which is depicted for the NaV1.7 pore, highlighting the DEKA motif, which permeates sodium ions.
Benedikt Nißl   +6 more
wiley   +1 more source

UPLC-PDA-Q Exactive Orbitrap-MS profiling of the lipophilic compounds product isolated from Eucalyptus viminalis plants

open access: yesHeliyon, 2020
The lipophilic compounds product (LCP), which was isolated and purified from Eucalyptus viminalis plants, has shown earlier broad antimicrobial and anti-inflammatory activities. To study secondary compounds responsible for the pharmacological activities,
Vladimir Ossipov   +3 more
doaj  

Developing HaloTag and SNAP‐Tag Chemical Inducers of Dimerization to Probe Receptor Oligomerization and Downstream Signaling

open access: yesAngewandte Chemie International Edition, EarlyView.
Controlling protein interactions is key to studying signaling. Antibody methods have limits, but chemical inducers of dimerization (CIDs) using HaloTags and SNAP‐Tags offer precise control. We present CIDs to covalently link heteromers with varied linkers and a FRET‐based sensor.
Michael Trumpp   +8 more
wiley   +1 more source

The Rearrangement of cis-2-en-4:6-diyn-oic Acids to alphabeta-Unsaturated gamma-Lactones. [PDF]

open access: bronze, 1957
Per Koch Christensen   +4 more
openalex   +1 more source

Recent Applications of the Simple Hydrocarbon Cyclooctatetrene as a Starting Material for Complex Molecule Synthesis [PDF]

open access: yes, 2012
Cyclooctatetraene [COT], a simple non-aromatic cyclic polyene, is capable of undergoing a variety of oxidation and cycloaddition reactions to afford polycyclic structures.
Donaldson, William, Glaeske, Kevin W
core   +2 more sources

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