Ring Formation in Sesquiterpene Synthesis: Biomimetic vs. Non‐Biomimetic Strategies
European Journal of Organic Chemistry, EarlyView.A short review of cyclase enzyme‐mediated ring formation in sesquiterpene biosynthesis is presented as a prelude to six case studies examining the merits and demerits of biomimetic vs. non‐biomimetic strategies for carbocyclisation in the total synthesis of this iconic natural product class.
Bohan Lin, Chen Dai, Alan C. Spivey
wiley +1 more source
European Journal of Organic Chemistry, EarlyView.An ATRA‐based, Ru‐photocatalyzed radical‐polar crossover reaction for the preparation of monoprotected dicarbonyl compounds is reported. This procedure is based on the capture of a cationic intermediate, arising from the radical step, with diverse nucleophiles.
Derek Mota‐Hernández +2 more
wiley +1 more source
Rewiring Yarrowia lipolytica toward triacetic acid lactone for materials generation
Proceedings of the National Academy of Sciences of the United States of America, 2018 Kelly A. Markham +9 more
semanticscholar +1 more source
Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review
Food Safety and Health, EarlyView.Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra +2 more
wiley +1 more source
Asymmetric Synthesis of Chiral δ-Lactones Containing Multiple Contiguous Stereocenters
, 2011 Jennifer Peed +6 more
openalex +2 more sources
The Relation Between the Structure of γ-Lactones and the Vaule of their Molecular Rotations—Presumption of Eight Unknown [M]D20 [PDF]
, 1950 Shukichi Yamana
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Photocatalytic production and biological activity of D-arabino-1,4-lactone from D-fructose
Scientific ReportsLactones play crucial roles in various fields, such as pharmaceuticals, food, and materials science, due to their unique structures and diverse biological activities.
Sho Usuki +9 more
doaj +1 more source
Helvetica Chimica Acta, EarlyView.Four stereogenic centers are formed diastereoselectively in one step from a cyclic (E,E)‐1,5‐diene system using an electrophilic addition reaction. Subsequent ozonolytic cleavage of the intact Z‐double bond, followed by intramolecular nucleophilic substitution, yields an octahydroterfurandione with a threo,cis,threo configuration, an arrangement found ...
Holger Schimanski +6 more
wiley +1 more source
Photocaged and Water‐Soluble Glucose Functionalization for Spatiotemporal Acidification Pathways
Helvetica Chimica Acta, EarlyView.Light‐controlled glucose release from a water‐soluble coumarin photocage enables spatiotemporal acid generation in enzyme‐driven chemical reaction networks. ABSTRACT The spatiotemporal control of complex molecular systems, such as chemical reaction networks (CRNs), requires reagents and reactive species that can be activated both efficiently and ...
Nikolai Hempel +2 more
wiley +1 more source
Bioassay-guided isolation of dehydrocostus lactone from Echinops kebericho as a leishmanicidal drug
HeliyonSeveral strains of Leishmania parasite are involved in the occurrence of leishmaniasis infections, which makes its prevention and treatment very challenging.
Bekri Melka Abdo +5 more
doaj +1 more source