Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley +1 more source
Sugar-Based Polyesters: From Glux-Diol Synthesis to Its Enzymatic Polymerization. [PDF]
Acciaretti F +9 more
europepmc +1 more source
Quantitative Determination of Lactones in Piper methysticum (Kava-Kava) by Supercritical Fluid Chromatography [PDF]
Adele Murauer, Markus Ganzera
openalex +1 more source
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve +6 more
wiley +1 more source
Development of a Stereoselective Synthesis of Isomers of (+)-Disorazole Z1's Lateral Chain. [PDF]
Bauer TJ +3 more
europepmc +1 more source
Nanoemulsions for Skin Delivery of Essential Oils: A Systematic Review
ABSTRACT Essential oils (EOs) are recognized for their multiple health benefits. However, their high volatility, low stability, and limited water solubility limit their effective application. This systematic review aims to assess the use of nanoemulsions as delivery systems for the topical administration of EOs, highlighting their efficacy, safety, and
Thais Leticia Moreira da Silva +3 more
wiley +1 more source
Unified Asymmetric Synthesis of Aryltetralin Lactone Cyclolignans via Conformation-Assisted Radical C-H Cyclization. [PDF]
Yin R, Wang X, Zhou R, Zhu L, Huang J.
europepmc +1 more source
Reaction of Olefins with Malonamide in the Presence of Manganese(III) Acetate. Formation of α,β-Unsaturated γ-Lactones and γ-Lactams [PDF]
Hiroshi Nishino
openalex +1 more source
PET trays pose recycling challenges due to multilayer structures with polyethylene (PE) tie‐layers and barrier materials. In this study, a delamination process using a hot alkaline solution was applied to postindustrial multilayer PET/PE thermoforming waste to recover PET flakes and produce sheets.
Isabela F. A. Daras +6 more
wiley +1 more source
Erratum to: The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases [Journal of Lipid Research 66/1 (2025) 100711]. [PDF]
Stukey GJ +9 more
europepmc +1 more source

