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Biosynthesis and chemical diversity of β-lactone natural products.
Natural product reports (Print), 2019Covering: up to 2018 β-Lactones are strained rings that are useful organic synthons and pharmaceutical warheads. Over 30 core scaffolds of β-lactone natural products have been described to date, many with potent bioactivity against bacteria, fungi, or ...
S. Robinson +2 more
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Journal of Agricultural and Food Chemistry, 2019
The mycotoxin zearalenone (ZEN) is a secondary metabolite produced mainly by Fusarium species. ZEN poses health hazards both for humans and animals, as a major contaminant in the food and feed industries.
Xinrui Yu +9 more
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The mycotoxin zearalenone (ZEN) is a secondary metabolite produced mainly by Fusarium species. ZEN poses health hazards both for humans and animals, as a major contaminant in the food and feed industries.
Xinrui Yu +9 more
semanticscholar +1 more source
Helenalin - A Sesquiterpene Lactone with Multidirectional Activity.
Current Drug Targets, 2019Sesquiterpene lactones, secondary metabolites of plants, present in a large number of species mostly from the Asteracea family, are used in the traditional medicine of many countries for the treatment of various pathological conditions.
Joanna Drogosz, A. Janecka
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CONVERSION OF LACTONE INTO LACTONE HEMITHIOACETAL AND SYNTHESIS OF ENOL LACTONE
Chemistry Letters, 1981Abstract Lactone hemithioacetal was synthesized in good yield from ω-phenylthiocarboxylic acid derived from lactone, and it was converted into enol lactone via the corresponding sulfoxide.
Masahito Ochiai +3 more
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Journal of Pharmaceutical Sciences, 1983
Preparation of some simple lactone analogues of picrotoxin and their biological evaluation is reported. Certain analogues possessed activity, but at potencies insufficient to warrant further work.
J D, McChesney, A F, Wycpalek
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Preparation of some simple lactone analogues of picrotoxin and their biological evaluation is reported. Certain analogues possessed activity, but at potencies insufficient to warrant further work.
J D, McChesney, A F, Wycpalek
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C R C Critical Reviews in Food Science and Nutrition, 1976
Lactones represent another important class of flavor compounds that have been found in a wide variety of foods although traditionally they have been mainly associated with dairy products. This review summarizes their occurrences in foods along with their formation pathways, sensory properties, and isolation, identification, and synthesis techniques ...
Joseph A. Maga, Ira Katz
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Lactones represent another important class of flavor compounds that have been found in a wide variety of foods although traditionally they have been mainly associated with dairy products. This review summarizes their occurrences in foods along with their formation pathways, sensory properties, and isolation, identification, and synthesis techniques ...
Joseph A. Maga, Ira Katz
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American Journal of Contact Dermatitis, 1996
Sesquiterpene lactones are a large, diverse group of chemicals found in several plant families that cause allergic contact dermatitis. The biological, botanical, allergenic, and structural significance of sesquiterpene lactones is explored as well as the clinical characteristics of cutaneous reactions.
E M, Warshaw, K A, Zug
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Sesquiterpene lactones are a large, diverse group of chemicals found in several plant families that cause allergic contact dermatitis. The biological, botanical, allergenic, and structural significance of sesquiterpene lactones is explored as well as the clinical characteristics of cutaneous reactions.
E M, Warshaw, K A, Zug
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Synthesis of (+)-trans-Whisky Lactone, (-)-cis-Whisky Lactone, (+)-Cognac Lactone and (+)-Eldanolide
HETEROCYCLES, 1993(+)-trans-Whisky lactone (5) and (-)-cis-whisky lactone (8), (+)-cognac lactone (9) and (+)-eldanolide (10) were synthesized starting from levoglucosenone (1) in optically pure ...
Takashi Ehata +7 more
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Preparation of lactones via tricarbonyliron–lactone complexes
J. Chem. Soc., Perkin Trans. 1, 1981A number of tricarbonyliron–lactone complexes have been prepared from vinyl oxirans by treatment with pentacarbonyliron. In certain cases two η3-allyl complexes were isolated from a single vinyl oxiran. Oxidation of the complexes by cerium(IV) ammonium nitrate in acetonitrile leads predominantly to β-lactones.
Gary D. Annis +3 more
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