Results 51 to 60 of about 136,021 (344)

Study on the total synthesis of velbanamine: Chemoselective dioxygenation of alkenes with PIFA via a stop-and-flow strategy

open access: yesBeilstein Journal of Organic Chemistry, 2013
A “stop-and-flow” strategy was developed for the chemoselective dioxygenation of alkenes with a PIFA-initiated cyclization. This method is conceived for the desymmetrization of seco-diene, and a series of substituted 5-hydroxymethyl-γ-lactones were ...
Huili Liu   +4 more
doaj   +1 more source

A Revised Structure and Assigned Absolute Configuration of Theissenolactone A

open access: yesMolecules, 2020
Antimicrobial bioassay-guided fractionation of Microcera larvarum led to the isolation of a γ-lactone with a furo[3,4-b]pyran-5-one bicyclic ring system (1) and three known compounds, (3S,4R)-4-hydroxymellein (2), (3S,4S)-4-hydroxymellein (3) and 7 ...
Melissa M. Cadelis   +5 more
doaj   +1 more source

Antibiofilm effect of C-10 massoia lactone toward polymicrobial oral biofilms

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2021
This study is aimed to test the efficacy of C-10 Massoia lactone in oral polymicrobial degradation. Polymicrobial of Streptococcus sanguinis, Streptococcus mutans, Lactobacillus acidophilus, and Actinomyces viscosus were studied.
Diyah Tri Utami   +4 more
doaj   +1 more source

Directed evolution of Vibrio fischeri LuxR for improved response to butanoyl-homoserine lactone [PDF]

open access: yes, 2007
LuxR is the 3-oxohexanoyl-homoserine lactone (3OC6HSL) dependent transcriptional activator of the prototypical acyl-homoserine lactone (AHL) quorum sensing system of Vibrio fischeri.
Arnold, Frances H.   +4 more
core   +3 more sources

Isolation of quinic acid from dropped Citrus reticulata Blanco fruits: its derivatization, antibacterial potential, docking studies, and ADMET profiling

open access: yesFrontiers in Chemistry
Citrus reticulata dropped fruits are generally discarded as waste, causing environmental pollution and losses to farmers. In the present study, column chromatography has been used to isolate quinic acid (1,3,4,5-tetrahydroxycyclohexane-1-carboxylic acid)
Heena   +5 more
doaj   +1 more source

Making of Massoia Lactone-Loaded and Food-Grade Nanoemulsions and Their Bioactivities against a Pathogenic Yeast

open access: yesJournal of Marine Science and Engineering, 2022
Nanoemulsions (NEs) have been made for improving the delivery and disperse of bioactive compounds. In this study, it was found that the best ingredients for the stable Massoia lactone-loaded and food-grade NEs making were 560.0 µL of Tween-80, 240.0 µL ...
Li Yuan   +4 more
doaj   +1 more source

Synthesis of enantiomeric polyhydroxyalkylpyrrolidines from 1,3-dipolar cycloadducts. Evaluation as inhibitors of a β-galactofuranosidase [PDF]

open access: yes, 2016
Enantiomeric 2,3,4-tris(hydroxyalkyl)-5-phenylpyrrolidines have been synthesized from the major cycloadducts obtained by the 1,3-dipolar cycloaddition of sugar enones with azomethine ylides derived from natural amino acids.
Oliveira Udry, Guillermo Alejandro   +3 more
core   +2 more sources

Endophytic Fungus Isolated From Achyrocline satureioides Exhibits Selective Antiglioma Activity—The Role of Sch-642305

open access: yesFrontiers in Oncology, 2018
Glioblastoma is the most devastating primary brain tumor. Current treatment is palliative, making necessary the development of new therapeutic strategies to offer alternatives to patients.
Nathalia Stark Pedra   +15 more
doaj   +1 more source

Tucumanin, a β-hydroxy-γ-lactone bistetrahydrofuranic acetogenin from Annona cherimolia, is a potent inhibitor of mitochondrial complex I [PDF]

open access: yes, 2004
A new β-hydroxy-γ-methyl-γ-lactone bistetrahydrofuranic acetogenin, tucumanin, with the infrequent symmetrical threo/trans/threo/trans/ threo relative configuration at the tetrahydrofuran rings was isolated from Annona cherimolia (Annonaceae) seeds.
Alvarez, Olga   +8 more
core   +1 more source

Intramolecular Lactones of Sialic Acids [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
The so-called “sialo-chemical-biology” has become an attractive research area, as an increasing number of natural products containing a sialic acid moiety have been shown to play important roles in biological, pathological, and immunological processes.
P. Rota   +4 more
openaire   +4 more sources

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