Results 61 to 70 of about 217,585 (392)
Frontiers in Cellular and Infection Microbiology, 2018 Quorum sensing systems regulate gene expression in response to bacterial population density. Acyl-homoserine lactones are a class of quorum sensing molecules found in cattle rumen that are thought to regulate the gene expression of enterohemorrhagic ...
Yang Yang +4 more
semanticscholar +1 more source
Contribution of microscopy for understanding the mechanism of action against trypanosomatids [PDF]
, 2018 Transmission electron microscopy (TEM) has proved to be a useful tool to study the ultrastructural alterations and the target organelles of new antitrypanosomatid drugs.
A Martinez-Palomo +90 more
core +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2013 A “stop-and-flow” strategy was developed for the chemoselective dioxygenation of alkenes with a PIFA-initiated cyclization. This method is conceived for the desymmetrization of seco-diene, and a series of substituted 5-hydroxymethyl-γ-lactones were ...
Huili Liu +4 more
doaj +1 more source
Molecules, 2019 Recent growth and diversification of sheep milk products means more sophisticated methods are required to ensure their flavour quality. The objective of this study was to compare four extraction techniques for the analysis of volatile compounds in sheep ...
Ryan High +3 more
doaj +1 more source
A grapevine cytochrome P450 generates the precursor of wine lactone, a key odorant in wine.
New Phytologist, 2017 Monoterpenes are important constituents of the aromas of food and beverages, including wine. Among monoterpenes in wines, wine lactone has the most potent odor.
Tina Ilc +10 more
semanticscholar +1 more source
Discovery of macrocyclic inhibitors of apurinic/apyrimidinic endonuclease 1 [PDF]
, 2019 Apurinic/apyrimidinic endonuclease 1 (APE1) is an essential base excision repair enzyme that is upregulated in a number of cancers, contributes to resistance of tumors treated with DNA-alkylating or -oxidizing agents, and has recently been identified as ...
Beglov, Dmitri +12 more
core +7 more sources
Advanced Materials, EarlyView.Metal‐free carbon catalysts enable the sustainable synthesis of hydrogen peroxide via two‐electron oxygen reduction; however, active site complexity continues to hinder reliable interpretation. This review critiques correlation‐based approaches and highlights the importance of orthogonal experimental designs, standardized catalyst passports ...
Dayu Zhu +3 more
wiley +1 more source
Frontiers in Oncology, 2018 Glioblastoma is the most devastating primary brain tumor. Current treatment is palliative, making necessary the development of new therapeutic strategies to offer alternatives to patients.
Nathalia Stark Pedra +15 more
doaj +1 more source
Chemoselective Polymerizations from Mixtures of Epoxide, Lactone, Anhydride, and Carbon Dioxide.
Journal of the American Chemical Society, 2016 Controlling polymer composition starting from mixtures of monomers is an important, but rarely achieved, target. Here a single switchable catalyst for both ring-opening polymerization (ROP) of lactones and ring-opening copolymerization (ROCOP) of ...
C. Romain +6 more
semanticscholar +1 more source