Functional characterization of the cytochrome P450 monooxygenase CYP71AU87 indicates a role in marrubiin biosynthesis in the medicinal plant Marrubium vulgare. [PDF]
, 2019 BackgroundHorehound (Marrubium vulgare) is a medicinal plant whose signature bioactive compounds, marrubiin and related furanoid diterpenoid lactones, have potential applications for the treatment of cardiovascular diseases and type II diabetes.
Addison, J Bennett +5 more
core +6 more sources
Molecules, 2016 The aim of this study was the chemical synthesis of a series of halo- and unsaturated lactones, as well as their microbial transformation products. Finally some of their biological activities were assessed. Three bicyclic halolactones with a methyl group
Katarzyna Wińska +8 more
doaj +1 more source
Molecules, 2018 Three novel enantiomeric pairs of bromolactones possesing a 2,5-dimethylphenyl substituent at the β-position of the lactone ring have been synthesized from corresponding enantiomeric (E)-3-(2′,5′-dimethylphenyl)hex-4-enoic acids (4) by ...
Witold Gładkowski +9 more
doaj +1 more source
Primary familial congenital erythrocytosis: two novel EPOR mutations found in Spain [PDF]
, 1997 Two-carbon ring expansions of vinyl β-lactones, were carried out by Lewis acids (BF3-Et2O or Et2AlCl) via an ionization/cation rearrangement. β,γ-unsaturated δ-lactones were produced as efficient protocols for the synthesis of bioactive substances. Vinyl
Bento, C. +3 more
core +2 more sources
Molecules, 2021 A total of nine sesquiterpenoid lactones together with phenolic compounds and other terpenes were identified from the crude methanol extract of Elephantopus mollis Kunth.
Gabin Thierry M. Bitchagno +6 more
doaj +1 more source
Scientific Opinion on Flavouring Group Evaluation 217, Revision 1 (FGE.217Rev1). Consideration of genotoxic potential for ?,?-unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: Lactones [PDF]
EFSA Journal, 2013 The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of 12 flavouring substances from subgroup 4.1 of FGE.19 in the Flavouring Group ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj +1 more source
Microbial Biosynthesis of Lactones: Gaps and Opportunities towards Sustainable Production
Applied Sciences, 2021 Lactones are volatile organic compounds widely present in foods. These chemicals are applied as flavors and fragrances in the food, cosmetics and pharmaceutical industries.
Rui Silva +3 more
doaj +1 more source
Secondary metabolites with ecologic and medicinal implications in Anthemis cretica subsp. petraea from Majella National Park [PDF]
, 2016 Anthemis cretica subsp. petraea (Ten.) Greuter is a plant belonging to the Asteraceae family and endemic of central Italy. In this paper, the first analysisof the ethanolic fraction of samples collected in the Majella National Park is reported.
Alessandro Venditti +7 more
core +2 more sources
Development of covalent triazine frameworks as heterogeneous catalytic supports [PDF]
, 2019 Covalent triazine frameworks (CTFs) are established as an emerging class of porous organic polymers with remarkable features such as large surface area and permanent porosity, high thermal and chemical stability, and convenient functionalization that ...
Krishnaraj, Chidharth +3 more
core +1 more source
Journal of Lipid Research, 2006 Serum paraoxonase (PON1) is a HDL-associated enzyme exhibiting potentially antiatherogenic properties. Here, we examined the common PON1-192R/Q human polymorphism. Despite numerous studies, the effect of this polymorphism on the antiatherogenic potential
Leonid Gaidukov +3 more
doaj +1 more source