Results 41 to 50 of about 11,690 (235)

“Lactose free” depression- Antidepressant with and without lactose registered in Croatia

European Psychiatry, 2023
Introduction Depression is a common illness worldwide, with an estimated 3.8% of the population affected, including 5.0% among adults and 5.7% among adults older than 60 years. Lactose intolerance affects 70% of the world population.
D. Svetinović, I. Barun, S. Vuk Pisk, I. Filipčić, V. Grošić   +4 more
doaj   +1 more source

Daily Lactose Supplementation in Lactase Non-Persistent Individuals Induces Colonic Adaptation and Reduces Intolerance Symptoms

Proceedings, 2023
Background and objectives: Globally, about 70% of the adult population is lactase non-persistent (LNP), lacking the enzyme required for lactose digestion.
Ellen Looijesteijn, Lonneke JanssenDuijghuijsen, Maartje van den Belt, Beatrix Gerhard, Renata Ariens, Reina Tjoelker, Jan Geurts   +6 more
doaj   +1 more source

Lactase Deficiency and Lactose Intolerance: Current Understanding and Future Directions

Journal of Education, Health and Sport
Introduction and purpose: Lactose, the primary carbohydrate in milk, requires the enzyme lactase for digestion. Deficiency in lactase activity leads to lactose intolerance, causing gastrointestinal symptoms.
Krystian RACHWAŁ, Karol Wielgus, Piotr Bator, Wiktor Razik, Grzegorz Łyko, Maria Antos, Julia Furgalska, Maria Pawłowska, Angelika Wawryszuk   +8 more
doaj   +1 more source

MTSS2‐Related Disorder: Refining the Phenotype in Four New Cases and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT MTSS2 encodes a protein highly expressed in the central nervous system, with a crucial role in neurodevelopment. The de novo recurrent variant c.2011C>T (p.Arg671Trp) was first identified in 2022 as cause of Intellectual Developmental Disorder with ocular anomalies and distinctive facial features (OMIM#620086).
Angela De Dominicis, Francesca Piceci Sparascio, Fabrizia Stregapede, Alessandra Terracciano, Daniela Verrigni, Francesca Romana Lepri, Sarah Cetola, Maria Lisa Dentici, Federico Vigevano, Antonio Novelli, Nicola Specchio, Marina Trivisano, Maria Cristina Digilio   +12 more
wiley   +1 more source

Mutarotational Kinetics and Glass Transition of Lactose [PDF]

Solid State Communications 140 (11/2006) 329-334, 2006
We report for the first time real time in situ and quantitative measurements of the mutarotation reaction of lactose in the solid state. The experiments have been performed by 13C NMR. We show that mutarotation is initiated on heating the amorphous state, and reaches chemical equilibrium close above the glass transition temperature Tg.
arxiv   +1 more source

Clinical Evaluation of Potential Interaction Between Bemnifosbuvir and Ruzasvir With an Assessment of Food Effect: Results of a Phase 1 Study in Healthy Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract A combination of nucleotide hepatitis C virus (HCV) nonstructural protein (NS) 5B and 5A inhibitors is a preferred standard of care for treating chronic HCV. Bemnifosbuvir is a novel oral guanosine nucleotide prodrug with potent pan‐genotypic inhibitory activity against HCV NS5B.
Xiao‐Jian Zhou, Gaetano Morelli, Maureen Montrond, Shannan Lynch, Keith Pietropaolo, Bruce Belanger, Arantxa Horga, Janet Hammond   +7 more
wiley   +1 more source

Inequality leads to the evolution of intolerance in reputation-based populations [PDF]

Chaos 33 (3), 033119 (2023)
This work studies the impact of economic inequality on the evolution of intolerance through a reputation-based model of indirect reciprocity. Results show that economic inequality is a powerful enhancer of intolerance, inducing the escalation of out-group discrimination even without the presence of new intolerant mutants.
arxiv   +1 more source

Fructose and/or Sorbitol Intolerance in a Subgroup of Lactose Intolerant Patients

Canadian Journal of Gastroenterology, 1994
The diagnosis and treatment of lactose intolerance often does not resolve all the symptoms of postcibal bloating and flatulence. Included in this study were 104 lactose intolerant patients (71 female, 33 male) who complained of residual postcibal ...
SR Mishkin, L Sablauskas, S Mishkin
doaj   +1 more source

Spreading of intolerance under economic stress: results from a model with reputation [PDF]

Physical Review E 90, 022805 (2014), 2014
When a population is engaged in successive prisoner's dilemmas, indirect reciprocity through reputation fosters cooperation through the emergence of moral and action rules. A simplified model has recently been proposed where individuals choose between helping or not others, and are judged good or bad for it by the rest of the population. The reputation
arxiv   +1 more source

Predicting the asymmetric response of a genetic switch to noise [PDF]

, 2008
We present a simple analytical tool which gives an approximate insight into the stationary behavior of nonlinear systems undergoing the influence of a weak and rapid noise from one dominating source, e.g. the kinetic equations describing a genetic switch with the concentration of one substrate fluctuating around a constant mean.
arxiv   +1 more source