Results 121 to 130 of about 7,301 (235)

Lactosylceramide is synthesized in the lumen of the Golgi apparatus

FEBS Letters, 1994
Recently, synthesis of lactosylceramide has been described to occur on the cytosolic face of the Golgi [(1991) J. Biol. Chem. 266, 20907‐20912]. The reactions following in the biosynthesis of higher glycosphingolipids are known to take place in the lumen of the Golgi.
Lannert, Heinrich, Bünning, Garsten, Jeckel, Dieter, Wieland, Felix T.   +3 more
openaire   +2 more sources

Accumulation of Unusual Gangliosides G_Q3 and G_P3 in Breast Cancer Cells Expressing the G_D3 Synthase

Molecules, 2012
Glycosphingolipids from the ganglio-series are usually classified in four series according to the presence of 0 to 3 sialic acid residues linked to lactosylceramide.
Agata Steenackers, Jorick Vanbeselaere, Aurélie Cazet, Marie Bobowski, Yoann Rombouts, Florent Colomb, Xuefen Le Bourhis, Yann Guérardel, Philippe Delannoy   +8 more
doaj   +1 more source

Neuromuscular synaptic function in mice lacking major subsets of gangliosides [PDF]

, 2008
Gangliosides are a family of sialylated glycosphingolipids enriched in the outer leaflet of neuronal membranes, in particular at synapses. Therefore, they have been hypothesized to play a functional role in synaptic transmission.
Ando, Ang, B. Todorov, B.C. Jacobs, Buchwald, Bullens, Chamberlain, Chen, Chiavegatto, Desplats, Egorushkina, F.M.P. Zitman, Fishman, Furuse, Gong, Green, H.J. Willison, Hakomori, Halstead, Halstead, Hashiramoto, Inoue, Isaev, J.J. Plomp, J.J. Verschuuren, K. Furukawa, K. Furukawa, Kaja, Kappel, Kawai, Lang, Ledeen, Ledeen, Liu, Magleby, Marconi, McLachlan, Meir, Nakatani, Ngamukote, O'Hanlon, Okada, Ortiz, Plomp, Proia, Rahmann, Ramirez, Roth, Salaun, Santafe, Sheikh, Simpson, Sohn, Sonnino, Stevens, Sugiura, Susuki, Svennerholm, Takamiya, Tanaka, Taverna, Tettamanti, Varoqueaux, Wang, Wieraszko, Willison, Wood, Wu, Wu, Wu, Wu, Yamashita, Yates   +72 more
core   +1 more source

Biosynthesis of Lactosylceramide and Triglycosylceramide by Galactosyltransferases from Rat Spleen

Journal of Biological Chemistry, 1969
Abstract The transfer of galactose from labeled uridine diphosphogalactose to glucosylceramide and to galactosyl-glucosylceramide (lactosylceramide) was shown to occur in incubations with rat spleen, brain, kidney, liver, and bone marrow preparations.
J, Hildebrand, G, Hauser
openaire   +2 more sources

Effect of membrane lipids on the lactosylceramide molecular species specificity of CMP-N-acetylneuraminate:lactosylceramide sialyltransferase

Journal of Lipid Research, 1993
It has previously been shown that when the molecular species specificity of rat liver Golgi CMP-N-acetylneuraminate:lactosylceramide alpha 2,3-sialyltransferase was determined, using as the substrate lactosylceramide (LacCer) incorporated into liposomes ...
H Kadowaki, MA Grant, LA Williams
doaj   +1 more source

Elastin-derived peptides potentiate atherosclerosis through the immune Neu1-PI3Kγ pathway [PDF]

, 2017
Aims Elastin is degraded during vascular ageing and its products, elastin-derived peptides (EP), are present in the human blood circulation. EP binds to the elastin receptor complex (ERC) at the cell surface, composed of elastin-binding protein (EBP), a ...
Berge, Elodie, Blaise, Sebastien, Castaing-Berthou, Audrey, Debelle, Laurent, Duca, Laurent, Fougerat, Anne, Garnotel, Roselyne, Gayral, Stephanie, Laffargue, Muriel, Malet, Nicole, Martinez, Laurent O., Martiny, Laurent, Maurice, Pascal, Montheil, Aurelie, Pshezhetsky, Alexey V., Wymann, Matthias P.   +15 more
core  

Intracellular localization of lactosylceramide, the major human neutrophil glycosphingolipid.

Journal of Biological Chemistry, 1987
The abundance of lactosylceramide (LacCer; Gal beta 1-4Glc beta 1-1Cer) in human polymorphonuclear neutrophils (PMN) (about 10(9) molecules/cell) seemed inconsistent with an exclusive plasma membrane LacCer localization in these cells. Therefore, the distribution of LacCer between plasma membrane and intracellular compartments was analyzed.
F W, Symington, W A, Murray, S I, Bearman, S, Hakomori   +3 more
openaire   +2 more sources

Glycolipid accumulation in bronchoalveolar space in adult respiratory distress syndrome.

Journal of Lipid Research, 1984
Surfactant lipids in the alveolar space are believed to play an important role in normal respiratory function. Although the surface-active phospholipids have been extensively studied, the possible role of glycolipids in the surfactant remains to be ...
H Rauvala, M Hallman
doaj   +1 more source

Lactosylceramide Mediates the Expression of Adhesion Molecules in TNF-α and IFNγ-stimulated Primary Cultured Astrocytes.

Korean Journal of Physiology and Pharmacology, 2011
Here we have investigated how lactosylceramide (LacCer) modulates gene expression of adhesion molecules in TNF-α and IFNγ (CM)-stimulated astrocytes. We have observed that stimulation of astrocytes with CM increased the gene expression of ICAM-1 and VCAM-
Jin-Koo Lee, Jin-Kyu Kim, Soo-Hyun Park, Y. Sim, Jun-Sub Jung, H. Suh   +5 more
semanticscholar   +1 more source

From elastin peptides to neuraminidase-1-dependent lactosylceramide generation

Comptes Rendus. Chimie, 2011
Elastin peptides constitute a group of biologically active peptides derived from the fragmentation of insoluble elastin. These molecules, currently termed elastokines, have been shown to interact preferably with the elastin receptor complex.
Rusciani, A., Duca, L., Brassart, B., Martiny, L., Debelle, L.   +4 more
openaire   +1 more source