Circulating sphingolipids in relation to cognitive decline and incident dementia: The Cardiovascular Health Study. [PDF]
Moseholm KF +10 more
europepmc +1 more source
Combined Weight Loss and Exercise Training Alters Skeletal Muscle Subcellular Lipid Localization and Intermuscular Adipose Tissue Cellular Composition. [PDF]
Zemski Berry K +19 more
europepmc +1 more source
Regulation of Glycosylation in Bone Metabolism. [PDF]
Hamamura K, Nagao M, Furukawa K.
europepmc +1 more source
Glycolipids implicated as mediators of clinically visible retinal pigment epithelial migration in age-related macular degeneration. [PDF]
Wang Z +4 more
europepmc +1 more source
Central Roles of Glucosylceramide in Driving Cancer Pathogenesis. [PDF]
Zhao X, Pandey MK.
europepmc +1 more source
Orchestrating Stress Responses in Multiple Sclerosis: A Role for Astrocytic IFNγ Signaling. [PDF]
Habean ML, Kaiser KE, Williams JL.
europepmc +1 more source
Effect of cholesterol on the lactosylceramide domains in phospholipid bilayers
Lactosylceramide (LacCer) in the plasma membranes of immune cells is an important lipid for signaling in innate immunity through the formation of LacCer-rich domains together with cholesterol (Cho). However, the properties of the LacCer domains formed in multicomponent membranes remain unclear.
Shinya Hanashima +6 more
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New Vis-Tas in Lactosylceramide Research
Advances in Experimental Medicine and Biology, 2014Lactosylceramide (LacCer) is a member of a large family of compounds collectively called the glycosphingolipids (GSL). These molecules are present in all mammalian cells, some bacteria and fungus. GSLs are composed of an amino acid serine, fatty acids and sugars and are usually localized on the cell surface wherein they serve as receptors for diverse ...
Subroto, Chatterjee +2 more
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Astrocyte-derived lactosylceramide implicated in multiple sclerosis
Nature Medicine, 2014Multiple sclerosis (MS) is a demyelinating autoimmune disease of the central nervous system. A new study has shown that the lipid lactosylceramide, produced by astrocytes, contributes to disease progression in a mouse model of MS.
Abdolmohamad, Rostami, Bogoljub, Ciric
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Galactocerebrosidase (GALC) hydrolyses galactose residues from various substrates, including galactosylceramide, psychosine (galactosylsphingosine), and lactosylceramide.
N. Papini +8 more
semanticscholar +1 more source

