Results 101 to 110 of about 37,464 (274)

PEG 3350 Versus Lactulose for Treatment of Functional Constipation in Children: Randomized Study

Journal of Pediatric Gastroenterology and Nutrition - JPGN, 2019
Objectives: The aim of this study was to compare the clinical efficacy and tolerance of polyethylene glycol 3350 (PEG) and lactulose for the treatment of functional constipation in infants and children. Methods: This randomized, multicenter study covered
D. Jarzębicka, Joanna Sieczkowska-Golub, J. Kierkuś, P. Czubkowski, M. Kowalczuk-Kryston, Maciej Pelc, D. Lebensztejn, B. Korczowski, P. Socha, G. Oracz   +9 more
semanticscholar   +1 more source

Identifying Drugs Associated With Parkinson's Disease Risk Using Machine Learning

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Machine learning (ML)–based methods have been proposed as a potential approach for identifying candidate drugs to be repurposed as disease‐modifying treatments for Parkinson's disease (PD). We applied an ML‐based signal detection method to identify drugs associated with PD and evaluated the method's generalizability.
Eeva Pylkkö, Émeline Courtois, Anne Paakinaho, Sirpa Hartikainen, Valtteri Kaasinen, Alexis Elbaz, Anne C. M. Thiébaut, Ismaïl Ahmed, Anna‐Maija Tolppanen   +8 more
wiley   +1 more source

Probiotics as Alternative Therapy for Psychometric Disorders in Hepatic Encephalopathy

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2020
Aim: To identify whether probiotics have the same effectiveness as lactulose in improving the results of psychometric testing in patients with hepatic encephalopathy. Method: Literature Searching were performed on Pubmed, EBSCOhost, Scopus, and Cochrane
Bany Faris Amin, Irfan Kresnadi, Vannessa Karenina, GM Yudi Prasetia A, Trivani Putri, Juferdy Kurniawan   +5 more
doaj   +1 more source

The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors [PDF]

, 2015
OBJECTIVE: Gut barrier is a functional unit organized as a multi-layer system and its multiple functions are crucial for maintaining gut homeostasis. Numerous scientific evidences showed a significant association between gut barrier leaking and gastro ...
Bruno, G, Franceschi, F, Gasbarrini, A, Lopetuso, Lr, Petito, V, Scaldaferri, F   +5 more
core  

Synthesis of Oligosaccharides Derived from Lactulose (OsLu) Using Soluble and Immobilized Aspergillus oryzae β-Galactosidase [PDF]

, 2016
β-Galactosidase from Aspergillus oryzae offers a high yield for the synthesis of oligosaccharides derived from lactulose (OsLu) by transgalactosylation.
Batista-Viera, F., Cardelle-Cobas, A., Corzo, N., Corzo-Martínez, M., Giacomini, C., Irazoqui, G., Olano, A.   +6 more
core   +4 more sources

Machine learning methods for predicting adverse drug events: A systematic review

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 422-444, February 2026.
Abstract Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...
Niaz Chalabianloo, Fatemeh Ahmadi, Mohammad Ali Omrani, Sheikh S. Abdullah, Neda Rostamzadeh, Atefeh Jafari, Lujain Izzedin, Kamran Sedig, Flory T. Muanda   +8 more
wiley   +1 more source

EVALUATION OF EFFICACY OF RIFAXIMIN IN THE TREATMENT OF HEPATIC ENCEPHALOPATHY IN PATIENTS WITH CIRRHOSIS

Gomal Journal of Medical Sciences, 2016
Background: Cirrhosis is a major cause of mortality and morbidity worldwide. It is also a frequent cause of hospital admissions. The objective of this study was to determine the efficacy of rifaximin and lactulose versus lactulose alone for the treatment
Hafsa Habib, Dur-e- Nayab, Zafar Hayat, Shahid Jamil, Habibullah Khan   +4 more
doaj  

Bifidobacteria metabolize lactulose to optimize gut metabolites and prevent systemic infection in patients with liver disease

Nature Microbiology, 2023
Matthew A. Odenwald, Huaiying Lin, C. Lehmann, N. Dylla, Cody G. Cole, Jake D Mostad, Téa E. Pappas, Ramanujam Ramaswamy, A. Moran, Alan L. Hutchison, Matthew R. Stutz, Mark Dela Cruz, Emerald Adler, Jaye Boissiere, M. Khalid, J. Cantoral, Fidel Haro, R. A. Oliveira, Emily Waligurski, T. Cotter, Samuel H. Light, K. Beavis, Anitha Sundararajan, A. Sidebottom, K. G. Reddy, Sonali Paul, Anjana Pillai, Helen S. Te, M. Rinella, Michael R. Charlton, E. Pamer, A. Aronsohn   +31 more
semanticscholar   +1 more source

Efficacy of low volume transanal irrigation in children with retentive fecal incontinence: A randomized controlled trial

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 2, Page 425-433, February 2026.
Abstract Objectives To assess whether low‐volume transanal irrigation (L‐TAI) is effective as add‐on to oral laxative therapy for children with functional constipation and retentive fecal incontinence. Methods Two‐arm randomized controlled trial, including children aged 4–14 suffering from retentive fecal incontinence.
Signe Øbo Larsen, Sofie Axelgaard, Iben Møller Jønsson, Bolette Brodersen, Simon Bang Kristensen, Birgitte Ryom Nielsen, Søren Hagstrøm, Luise Borch   +7 more
wiley   +1 more source

Effects of inulin and lactulose on the intestinal morphology of calves

Animal, 2010
For some time now prebiotics have been proposed to improve health by stimulation of beneficial bacteria in the intestine of humans and animals. The current study is aiming to show effects of feeding of either 2% inulin or 2% lactulose in milk replacer on
S. Masanetz, N. Wimmer, C. Plitzner, E. Limbeck, W. Preißinger, M.W. Pfaffl   +5 more
doaj   +1 more source