Results 91 to 100 of about 17,924 (204)

Lactulose Biosynthesis with Enzymes of Lactose-Fermenting Micromycetes and Bacteria

open access: yesТехника и технология пищевых производств
Lactulose is a well-studied prebiotic popular in medicine and the food industry. β-Galactosidases offer an alternative to traditional chemical methods of lactulose production. The article describes lactulose biosynthesis with crude enzyme preparations of
Svetlana A. Ryabtseva   +6 more
doaj   +1 more source

METH-Induced Neurotoxicity Is Alleviated by Lactulose Pretreatment Through Suppressing Oxidative Stress and Neuroinflammation in Rat Striatum

open access: yesFrontiers in Neuroscience, 2018
Abuse of methamphetamine (METH) results in neurological and psychiatric abnormalities. Lactulose is a poorly absorbed derivative of lactose and can effectively alleviate METH-induced neurotoxicity in rats.
Xiao-Li Xie   +4 more
doaj   +1 more source

Review Article: The Impact of the Gut Microbiome on Ulcerative Colitis Pharmacotherapy

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 6, Page 729-747, September 2026.
The gut microbiome modulates ulcerative colitis pharmacotherapy through microbial drug metabolism, immune regulation and altered drug bioavailability. Microbial composition influences response to aminosalicylates, corticosteroids, immunomodulators, biologics and small molecules, while microbiome‐targeted therapies show emerging promise.
Kate Collins   +6 more
wiley   +1 more source

Medication Reconciliation in Outpatient Psychiatry: An Indicator of Communication With Primary Care? A Quantitative Descriptive Study

open access: yesJournal of Advanced Nursing, Volume 82, Issue 9, Page 8658-8670, September 2026.
ABSTRACT Aims To quantify medication discrepancies between an outpatient psychiatric service and general practitioners in northern France, and investigate general practitioner identification in psychiatric records. Design Quantitative, exploratory, retrospective, descriptive, monocentric study.
Gwladys Acoulon   +5 more
wiley   +1 more source

Design and application of a lactulose biosensor

open access: yes, 2017
In this study the repressor of Escherichia coli lac operon, LacI, has been engineered for altered effector specificity. A LacI saturation mutagenesis library was subjected to Fluorescence Activated Cell Sorting (FACS) dual screening.
Dandan Xiong   +8 more
core   +1 more source

Lactulose for minimal hepatic encephalopathy in patients with extrahepatic portal vein obstruction

open access: yesThe Saudi Journal of Gastroenterology, 2012
Background/Aims: Minimal hepatic encephalopathy (MHE) is common in patients with extrahepatic portal vein obstruction (EHPVO). There is no study on the treatment of MHE using lactulose in patients with EHPVO.
Praveen Sharma, Barjesh Chander Sharma
doaj   +1 more source

Fatigue and Cognitive Impairment in Adults With Primary Sclerosing Cholangitis: Results From Concept Elicitation Interviews

open access: yesLiver International, Volume 46, Issue 9, September 2026.
ABSTRACT Background and Aims To understand the experience of fatigue and cognitive impairment in adults with symptomatic primary sclerosing cholangitis (PSC) as an essential first step towards developing PSC‐specific symptom measures. Methods Purposeful sampling was used to identify 17 symptomatic adults from the PSC Symptom Assessment Project who met ...
Donna M. Evon   +11 more
wiley   +1 more source

Betwixt playing the waiting game and waiting in vain: Temporal governance and the thin alignment of care under universal health coverage in Kenya

open access: yesMedical Anthropology Quarterly, Volume 40, Issue 3, September 2026.
Abstract This article investigates how Kenyan citizens access healthcare within the framework of Universal Health Coverage (UHC) reforms. Based on ethnographic fieldwork, it reconceptualizes waiting as a politically structured phenomenon rather than a simple delay. The analysis shows that UHC reforms do not eliminate waiting but instead redistribute it,
Edwin Ambani Ameso
wiley   +1 more source

Effect of oral lactulose on clinical and immunohistochemical parameters in patients with inflammatory bowel disease: a pilot study

open access: yesBMC Gastroenterology, 2007
Background The prebiotic potential of lactulose is well established and preclinical studies demonstrated a protective effect of lactulose in murine models of colitis.
Manns Michael P   +5 more
doaj   +1 more source

Effect of an Integrated Early Enteral Nutrition Management Protocol on Nutritional Target Attainment in Mechanically Ventilated ICU Patients: A Quasi‐Experimental Study Guided by the MRC Framework

open access: yesNursing in Critical Care, Volume 31, Issue 5, September 2026.
ABSTRACT Background Achieving early enteral nutrition (EN) targets remains challenging in mechanically ventilated intensive care unit (ICU) patients. Evidence for nursing‐led multicomponent protocols incorporating traditional Chinese medicine (TCM) approaches is limited.
Jie Zhang   +5 more
wiley   +1 more source

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