Results 71 to 80 of about 13,522 (173)

Clinical Trial: Lemborexant Efficacy and Safety in Liver Cirrhosis—Randomized, Double‐Blind, Crossover Clinical Trial

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 4, Page 458-470, August 2026.
RESTORE is a prospective, double‐blind, placebo‐controlled, crossover trial evaluating Lemborexant in cirrhosis at Cipto Mangunkusumo National Referral Hospital. Both 5 and 10 mg doses reduced PSQI by week 2, with sustained benefits post‐crossover. The 5 mg group improved Stroop Test performance, whereas the 10 mg group had prolonged reaction time ...
Rino Alvani Gani, Pitt Akbar, Irsan Hasan, Andri Sanityoso Sulaiman, Cosmas Rinaldi Adithya Lesmana, Juferdy Kurniawan, Sarah Melissa Panjaitan, Valerie Josephine Dirjayanto   +7 more
wiley   +1 more source

Lactulose for minimal hepatic encephalopathy in patients with extrahepatic portal vein obstruction

The Saudi Journal of Gastroenterology, 2012
Background/Aims: Minimal hepatic encephalopathy (MHE) is common in patients with extrahepatic portal vein obstruction (EHPVO). There is no study on the treatment of MHE using lactulose in patients with EHPVO.
Praveen Sharma, Barjesh Chander Sharma
doaj   +1 more source

Neurofilament Light Chain in Cerebrospinal Fluid and Blood Identifies Patients With Minimal and Overt Hepatic Encephalopathy

Liver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background Minimal hepatic encephalopathy (MHE) is an underdiagnosed complication of liver cirrhosis, associated with progression to overt hepatic encephalopathy (HE). The Portosystemic Hepatic Encephalopathy Score (PHES) is the recommended diagnostic standard, but its use is hindered by resource constraints and limited accuracy. Neurofilament
Elise Jonasson, Lea L. Grønkjær, Birgitte G. Jacobsen, Dorte A. Olsen, Charlotte W. Wernberg, Jens Kuhle, Jonna S. Madsen, Tobias Sejbaek, Mette M. Lauridsen   +8 more
wiley   +1 more source

Lactulose

Nursing times, 2006
europepmc   +2 more sources

The Role of Gut Microbiota in Liver Regeneration After Partial Hepatectomy: New Evidence From Animal and Human Studies

The FASEB Journal, Volume 40, Issue 14, 31 July 2026.
Partial hepatectomy (PH) reshapes gut microbiota composition, resulting in the release of microbial metabolites and components, including short chain fatty acids (SCFAs)/β‐hydroxybutyric acid (BHB), bacterial DNA and extracellular vesicles (EVs), bile acids (deoxycholic acid, DCA), and aminobenzoate degradation products.
Roberto Loi, Gabriella Simbula, Andrea Caddeo, Monica Pibiri   +3 more
wiley   +1 more source

Comparison of preference and safety of powder and liquid lactulose in adult patients with chronic constipation

Clinical and Experimental Gastroenterology, 2010
Charles F Barish1, Bryan Voss2, Byron Kaelin21Wake Research Associates, Raleigh, North Carolina, USA; 2Cumberland Pharmaceuticals Inc., Nashville, Tennessee, USABackground: Chronic constipation is an important clinical condition which can result in ...
Charles F Barish, Bryan Voss, Byron Kaelin   +2 more
doaj  

Efficacy Comparison of Nitazoxanide Combined with Lactulose versus Lactulose Monotherapy in Managing Overt Hepatic Encephalopathy

Journal of Rawalpindi Medical College
Objective: To evaluate the efficacy of combining Nitazoxanide with lactulose compared to lactulose alone in the treatment of overt hepatic encephalopathy.
Taimoor Hafeez Janjua, Amanat Ali, Sameer Ahmed, Sabeen Shakir, Zunera Rashid, Asma Irfan   +5 more
doaj   +1 more source

Correction to “The Dynamic Evolution of Lipid Profiles Following Transjugular Intrahepatic Portosystemic Shunt in Patients With Liver Cirrhosis”

Portal Hypertension &Cirrhosis, EarlyView.
wiley   +1 more source

Prevention of peptic ulcer by aqueous extract of Aegle marmelos leaf in rats

IMC Journal of Medical Science, 2018
Background and objectives: Minimal hepatic encephalopathy (MHE) impairs health related quality of life and predicts overt hepatic encephalopathy (HE) in cirrhotic patients. Lactulose is effective in the treatment of MHE.
Sharmin Rahman, Mohammad Rezaul Quader, Md. Ismail Khan   +2 more
doaj  

Factors associated with non-response to lactulose therapy in cirrhotic patients with minimal hepatic encephalopathy

IMC Journal of Medical Science, 2018
Background and objectives: Minimal hepatic encephalopathy (MHE) impairs health related quality of life and predicts overt hepatic encephalopathy (HE) in cirrhotic patients. Lactulose is effective in the treatment of MHE.
Shireen Ahmed, Md. Golam Azam, Indrajit Kumar Datta, Md. Nazmul Hoque, Tareq M Bhuiyan   +4 more
doaj