Results 61 to 70 of about 13,522 (173)

IBS with constipation: new possibilities for drug therapy

Лечащий Врач
Background. Irritable bowel syndrome with a predominance of constipation is a common chronic pathology in the population. The main drug therapy for irritable bowel syndrome with a predominance of constipation remains the prescription of laxatives. One of
M. V. Chernogorova, E. A. Medvedeva, G. L. Yurenev   +2 more
doaj   +1 more source

Modified Manual Therapeutic Plasma Exchange Technique as a Successful Treatment for Postattenuation Neurological Signs (PANS) in a Dog

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To investigate and describe the therapeutic potential of manual plasma exchange for controlling seizures and neurologic dysfunction in a dog with postattenuation neurologic signs (PANS). Case Summary A 4‐year‐old neutered female Yorkshire Terrier was initially diagnosed using computed tomography with a congenital extrahepatic ...
Marcos Fumero‐Hernández, Marta Ribas, Patricia Bou, Carlos Torrente, Luis Bosch   +4 more
wiley   +1 more source

Rapid Transgalactosylation Towards Lactulose Synthesis in a Small-scale Enzymatic Membrane Reactor (EMR)

Chemical Engineering Transactions, 2014
A small-scale EMR system was developed with a reliable control design giving the possibility for continuous operation at constant flux (constant hydraulic residence time, tHRT).
A.B. Sitanggang, A. Drews, M. Kraume
doaj   +1 more source

Effect of foot immersion and neck cooling on renal, intestinal, immune and inflammatory markers in older adults exposed to extreme heat

Experimental Physiology, EarlyView.
Abstract Older adults with reduced thermoregulatory capabilities are increasingly at risk of heat‐related pathophysiological outcomes (e.g., acute kidney injury, heatstroke) due to increasingly frequent, prolonged and intense heatwaves. Foot immersion and neck cooling have been proposed as practical, non‐electrical cooling strategies for protecting ...
Thomas McCarthy, Ben J. Lee, James J. McCormick, Kelli E. King, Emma R. McCourt, Luana C. Main, Robert D. Meade, Glen P. Kenny   +7 more
wiley   +1 more source

Fatigue and Cognitive Impairment in Adults With Primary Sclerosing Cholangitis: Results From Concept Elicitation Interviews

Liver International, Volume 46, Issue 9, September 2026.
ABSTRACT Background and Aims To understand the experience of fatigue and cognitive impairment in adults with symptomatic primary sclerosing cholangitis (PSC) as an essential first step towards developing PSC‐specific symptom measures. Methods Purposeful sampling was used to identify 17 symptomatic adults from the PSC Symptom Assessment Project who met ...
Donna M. Evon, Kaya Merkler, Laura Mkumba, Nicole Lucas, Lauren Wright, Joanne Hatchett, Rachel Gomel, Patrick J. Smith, Sasha Deutsch‐Link, Christopher L. Bowlus, Mark G. Swain, Bryce B. Reeve   +11 more
wiley   +1 more source

Disulfiram‐Induced Hepatotoxicity in a Patient With Alcohol Use Disorder: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Disulfiram can cause severe and potentially fatal hepatotoxicity, particularly in patients with preexisting liver disease. In Bhutan, where alcohol‐related liver disease represents a major public health burden and pharmacological options for relapse prevention remain limited, careful patient selection, hepatic assessment, and early monitoring ...
Sonam Wangchuk, Bikram Chhetri, Jiann Lin Loo   +2 more
wiley   +1 more source

Lactulose Biosynthesis with Enzymes of Lactose-Fermenting Micromycetes and Bacteria

Техника и технология пищевых производств
Lactulose is a well-studied prebiotic popular in medicine and the food industry. β-Galactosidases offer an alternative to traditional chemical methods of lactulose production. The article describes lactulose biosynthesis with crude enzyme preparations of
Svetlana A. Ryabtseva, Maria A. Shpack, Aleksei D. Lodygin, Alexander V. Serov, Serafima N. Sazanova, Marina V. Skorokhodova, Vera Yu. Romakhova   +6 more
doaj   +1 more source

Splenic lymphoid hyperplasia in a cat presenting with hyperammonaemia, hypercalcaemia and hypercobalaminaemia

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract A 5‐year‐old, male neutered, Bengal‐cross cat presented with progressive neurological signs (ataxia and torticollis). Initial haematology, serum biochemistry and electrolytes (including calcium) were unremarkable; however, ammonia was markedly elevated.
Kerry E. Rolph, Tim Scase, Owen Davies
wiley   +1 more source

METH-Induced Neurotoxicity Is Alleviated by Lactulose Pretreatment Through Suppressing Oxidative Stress and Neuroinflammation in Rat Striatum

Frontiers in Neuroscience, 2018
Abuse of methamphetamine (METH) results in neurological and psychiatric abnormalities. Lactulose is a poorly absorbed derivative of lactose and can effectively alleviate METH-induced neurotoxicity in rats.
Xiao-Li Xie, Wen-Tao Zhou, Kai-Kai Zhang, Li-Jian Chen, Qi Wang   +4 more
doaj   +1 more source

Ammonia Metabolism in the Aging Liver: Emerging Mechanistic Insights

Aging Cell, Volume 25, Issue 8, August 2026.
Liver aging may weaken ammonia‐detoxification reserve by disrupting mitochondrial ureagenesis, GS‐mediated scavenging, glutamine metabolism, and metabolic zonation. This emerging framework links impaired nitrogen handling to potential hepatic stress amplification and systemic crosstalk, while highlighting the need for direct validation in physiological
Heng Zhang, Guangyu Liang, Anding Liu
wiley   +1 more source