Results 121 to 130 of about 33,291 (295)

Antibiotic Exposure and Risk of Allograft Rejection and Survival After Liver Transplant: An Observational Cohort Study From a Tertiary Referral Centre

Transplant Infectious Disease, EarlyView.
Because the relationship between the gut microbiota and liver transplant outcomes is not well described, it is possible that there are, as yet, unrecognized negative impacts of antibiotic exposures on key liver transplant‐related outcomes. We observed a negative association between antibiotic exposures, particularly those with an anaerobic spectrum of ...
Olivia C. Smibert, Sara Vogrin, Marie Sinclair, Avik Majumdar, Mohamed Nasra, Dinesh Pandey, Hossein Jahanabadi, Jason A. Trubiano, Kate A. Markey, Monica A. Slavin, Adam Testro, Jason C. Kwong   +11 more
wiley   +1 more source

Magnetic Resonance Imaging Reveals Novel Insights into the Dual Mode of Action of Bisacodyl: A Randomized, Placebo‐controlled Trial in Constipation

Clinical Pharmacology &Therapeutics, Volume 117, Issue 5, Page 1284-1291, May 2025.
Bisacodyl is a widely used laxative that stimulates both motility and secretion. Our aim was to exploit the unique capabilities of MRI to define bisacodyl's mode of action. Two placebo‐controlled cross‐over trials were performed, one using a single dose of Bisacodyl 5 mg while the second dosed daily for 3 consecutive days.
Abdulsalam Aliyu, Neele Dellschaft, Caroline Hoad, Hannah Williams, Emily Gaudoin, Sarah Sulaiman, Colin Crooks, Penny Gowland, Alexia Aran, Robert Lange, Beatrice Bois De Fer, Maura Corsetti, Luca Marciani, Robin Spiller   +13 more
wiley   +1 more source

Assessment of intestinal inflammation via fecal calprotectin for early prediction of adverse outcomes in advanced chronic liver disease

United European Gastroenterology Journal, Volume 13, Issue 3, Page 305-316, April 2025.
Abstract Background and aims Intestinal inflammation assessed by fecal calprotectin (F‐CAL) in advanced chronic liver disease (ACLD) may represent an early sign of intestinal barrier dysfunction. We aimed to explore the usefulness of F‐CAL testing in ACLD in the prediction of adverse outcomes (AO, death, or LT) and refinement of prognostic ...
Tomas Koller, Petra Vrbova, Natalia Kubanek, Daniela Zilincanova, Svetlana Adamcova Selcanova, Daniel Jan Havaj, Lubomir Skladany   +6 more
wiley   +1 more source

Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose [PDF]

, 2012
Bifidogenic effect and stimulation of short chain fatty acid (SCFA) production by fractions of oligosaccharides with a DP≥3 and Gal β(1-6) linkages synthesised from lactose or lactulose by Pectinex Ultra SP-L and Lactozym 3000 L HP G were evaluated in ...
Cardelle-Cobas, Alejandra, Fernández García, María, González de los Reyes-Gavilán, Clara, Martínez Villaluenga, Cristina, Ruas-Madiedo, Patricia, Salazar, Nuria, Villamiel, Mar   +6 more
core   +1 more source

Combination of rifaximin and lactulose improves clinical efficacy and mortality in patients with hepatic encephalopathy

Drug Design, Development and Therapy, 2018
Background Rifaximin and lactulose are common effective agents for hepatic encephalopathy (HE). Whether a combination of rifaximin and lactulose improves the efficacy and mortality in patients with HE compared with lactulose alone needs to be analyzed.
Zhida Wang, Pei Chu, Wen-jin Wang
semanticscholar   +1 more source

Lactulose for minimal hepatic encephalopathy in patients with extrahepatic portal vein obstruction

The Saudi Journal of Gastroenterology, 2012
Background/Aims: Minimal hepatic encephalopathy (MHE) is common in patients with extrahepatic portal vein obstruction (EHPVO). There is no study on the treatment of MHE using lactulose in patients with EHPVO.
Praveen Sharma, Barjesh Chander Sharma
doaj   +1 more source

Is Lactulose Plus Rifaximin Better Than Lactulose Alone In The Management Of Hepatic Encephalopathy?

Journal of the College of Physicians and Surgeons Pakistan, 2018
To compare the efficacy of lactulose plus rifaximin with efficacy of lactulose alone in the treatment of hepatic encephalopathy.A randomized controlled trial.Department of Medicine, Jinnah Hospital, Lahore, from December 2014 to June 2015.All patients who presented with hepatic encephalopathy due to decompensated chronic liver disease were randomly ...
Nauman Ismat Butt, Aniqa Anser Tufail Khan Kakar, Arif Mahmood Siddiqui, Usman Ismat Butt, Tashia Malik   +4 more
openaire   +2 more sources

Stability of oligosaccharides derived from lactulose during the processing of milk and apple juice [PDF]

, 1994
The scientific evidence on the bioactivity of oligosaccharides from lactulose has encouraged us to study their physicochemical modifications during the processing of milk and apple juice.
A Aho, A Chandra, AL Buchsbaum, D Jacobs, F Afrati, F Bancilhon, F Bancilhon, F Bry, G Dong, G Dong, G Dong, GF Italiano, GG Hillerbrand, H Jakobsson, J. W. Lloyd, JM Nicolas, JW Lloyd, KR Apt, KR Apt, M Vardi, MH Emden, S Abiteboul, T Ibaraki, X Qian, Y Ioannidis   +24 more
core   +1 more source

EB 2017 Article: Interpretation of the lactulose:mannitol test in rural Malawian children at risk for perturbations in intestinal permeability

Experimental biology and medicine, 2018
The dual sugar absorption test, specifically the lactulose:mannitol test, is used to assess gut health. Lactulose absorption is said to represent gut damage and mannitol absorption is used as a measure of normal small bowel function and serves as ...
M. I. Ordiz, Caroline C. Davitt, Kevin B. Stephenson, Sophia E. Agapova, O. Divala, N. Shaikh, M. Manary, M. Manary, M. Manary   +8 more
semanticscholar   +1 more source

COMPARISON OF RIFAXIMIN PLUS LACTULOSE WITH THE LACTULOSE ALONE FOR THE TREATMENT OF HEPATIC ENCEPHALOPATHY

, 2020
Hepatic encephalopathy is a stimulating complication of liver dysfunction. Therapeutic options for hepatic encephalopathy are currently limited and present significant risks and benefits associated with its use. Rifaximin is a new antimicrobial agent with a broad spectrum of activity that has shown promising results as an alternative option for liver ...
openaire   +1 more source