Primer investigation of RIG-I-like receptors expression in virus infection with the acute character [PDF]
This study investigates the expression of RIG-I-like receptors (RLRs) – RIG-I, MDA5, and LGP2 – in Lagovirus europaeus /GI.2 infections causing Rabbit Hemorrhagic Disease.
Filip Lewandowski +4 more
doaj +3 more sources
Epidemiology of RHDV2 (Lagovirus europaeus/GI.2) in free-living wild European rabbits in Portugal
As the detection of the first outbreak of a novel aetiological agent of rabbit haemorrhagic disease commonly called RHDV2 or RHDVb (Lagovirus europaeus/GI.2, henceforth GI.2) in France in 2010, the virus rapidly spread throughout continental Europe and ...
CARLOS Rouco +2 more
exaly +6 more sources
MicroRNAs Regulate the Expression of Genes Related to the Innate Immune and Inflammatory Response in Rabbits Infected with Lagovirus europaeus GI.1 and GI.2 Genotypes. [PDF]
MicroRNAs (miR) are a group of small, non-coding RNAs of 17–25 nucleotides that regulate gene expression at the post-transcriptional level. Dysregulation of miRNA expression or function may contribute to abnormal gene expression and signaling ...
Ostrycharz-Jasek E +4 more
europepmc +4 more sources
Large-scale lagovirus disease outbreaks in European brown hares (Lepus europaeus) in France caused by RHDV2 strains spatially shared with rabbits (Oryctolagus cuniculus) [PDF]
Rabbit haemorrhagic disease virus (RHDV) is a lagovirus that causes rabbit haemorrhagic disease (RHD) in European rabbits (Oryctolagus cuniculus). In 2010, a new genotype called RHDV2 emerged in France. It exhibits a larger host range than classical RHDV
Ghislaine Le Gall-Reculé +7 more
doaj +6 more sources
Evaluation of autophagic and apoptotic markers during infection with animal virus causing hemorrhagic fever in rabbits [PDF]
IntroductionLagovirus europaeus/GI.1 and GI.2 cause severe Rabbit Haemorrhagic Disease, and immune processes are among the important pathomechanisms of the disease.
Dominika Bębnowska +15 more
doaj +4 more sources
Recombination at the emergence of the pathogenic rabbit haemorrhagic disease virus Lagovirus europaeus/GI.2 [PDF]
AbstractRabbit haemorrhagic disease is a viral disease that emerged in the 1980s and causes high mortality and morbidity in the European rabbit (Oryctolagus cuniculus). In 2010, a new genotype of the rabbit haemorrhagic disease virus emerged and replaced the former circulating Lagovirus europaeus/GI.1 strains.
Joana Abrantes +2 more
exaly +5 more sources
Etiology of viral induced acute liver failure and defensins as potential therapeutic agents in ALF treatment [PDF]
Acute liver failure (ALF) is a rare and severe disease, which, despite continuous advances in medicine, is still characterized by high mortality (65-85%). Very often, a liver transplant is the only effective treatment for ALF.
Rafał Hrynkiewicz +1 more
doaj +2 more sources
An RT-qPCR Assay from Rectal Swabs for the Detection of Rabbit Hemorrhagic Disease Virus 2 in Natural Cases. [PDF]
Rabbit hemorrhagic disease virus 2 (RHDV2 or Lagovirus europaeus GI.2) is spreading across North America. This has enabled submissions of lagomorphs for testing to veterinary diagnostic laboratories (VDLs). The liver is currently the gold‐standard sample type for testing by RT‐qPCR.
Asin J +6 more
europepmc +2 more sources
Factors affecting RIG-I-Like receptors activation - New research direction for viral hemorrhagic fevers [PDF]
Viral hemorrhagic fever (VHF) is a term referring to a group of life-threatening infections caused by several virus families (Arenaviridae, Bunyaviridae, Filoviridae and Flaviviridae).
Paulina Małkowska +2 more
doaj +2 more sources
Pathological and virological insights from an outbreak of European brown hare syndrome in the Italian hare (Lepus corsicanus) [PDF]
European brown hare syndrome (EBHS) is a highly contagious and fatal viral disease, mainly affecting European brown hares (Lepus europaeus). The etiological agent, EBHS virus (EBHSV), belongs to the Lagovirus genus within the Caliciviridae family.
Mariagiovanna Domanico +18 more
doaj +2 more sources

