Results 21 to 30 of about 7,926 (103)

A new HaCV-EBHSV recombinant lagovirus circulating in European brown hares (Lepus europaeus) from Catalonia, Spain [PDF]

Scientific Reports
In 2020/2021, several European brown hare syndrome virus (EBHSV) outbreaks were recorded in European hares (Lepus europaeus) from Catalonia, Spain. Recombination analysis combined with phylogenetic reconstruction and estimation of genetic distances of ...
Tereza Almeida, Ana M. Lopes, Josep Estruch, Carlos Rouco, Patrizia Cavadini, Aleksija Neimanis, Dolores Gavier-Widén, Ghislaine Le Gall-Reculé, Roser Velarde, Joana Abrantes   +9 more
doaj   +11 more sources

Evaluation of autophagic and apoptotic markers during infection with animal virus causing hemorrhagic fever in rabbits [PDF]

Frontiers in Microbiology
IntroductionLagovirus europaeus/GI.1 and GI.2 cause severe Rabbit Haemorrhagic Disease, and immune processes are among the important pathomechanisms of the disease.
Dominika Bębnowska, Dominika Bębnowska, Sylwia Rzeszotek, Agnieszka Kolasa, Karolina Wiśniewska, Karolina Wiśniewska, Magdalena Żabińska, Aneta Szulc, Zuzanna Cyske, Zuzanna Cyske, Karolina Pierzynowska, Karolina Pierzynowska, Aleksandra Wilk, Paulina Niedźwiedzka-Rystwej, Paulina Niedźwiedzka-Rystwej, Paulina Niedźwiedzka-Rystwej   +15 more
doaj   +4 more sources

Reactivity of Selected Markers of Innate and Adaptive Immunity in Rabbits Experimentally Infected With Antigenic Variants of RHD (Lagovirus europaeus/GI.1a) [PDF]

Veterinary Research Communications, 2022
AbstractLagovirus europaeus/GI.1 causes a fatal viral condition in rabbits characterized by acute viral hepatitis and disseminated intravascular coagulation. Due to rapid viral and environmental changes variants (Lagovirus europaeus/GI.1a and GI.2) have appeared and few immunological studies were performed.
Wiesław Deptuła, Beata Tokarz-Deptuła, Paulina Niedźwiedzka-Rystwej   +2 more
exaly   +5 more sources

An Outbreak of Rabbit Hemorrhagic Disease (RHD) Caused by Lagovirus europaeus GI.2/Rabbit Hemorrhagic Disease Virus 2 (RHDV2) in Ehime, Japan [PDF]

Journal of Veterinary Medical Science, 2021
A total of ten 1-2-year-old rabbits died within 2 weeks at a facility in Ehime prefecture in May 2019. Necropsy revealed liver discoloration and fragility, hemorrhage of some organs and blood coagulation failure. On histopathologic examination, necrotizing hepatitis was a common finding, together with fibrin thrombi in the small vessels and hemorrhage ...
Osamu Mikami, Ayako Miyazaki
exaly   +5 more sources

Apoptotic Cell Death in an Animal Model of Virus-Induced Acute Liver Failure-Observations during Lagovirus europaeus/GI.2 Infection. [PDF]

Int J Mol Sci
Lagovirus europaeus/GI.2 causes severe and highly fatal Rabbit Hemorrhagic Disease (RHD). Because of its characteristics, this infection is used as an animal model for acute liver failure (ALF).
Bębnowska D, Hrynkiewicz R, Rzeszotek S, Freus M, Poniewierska-Baran A, Niedźwiedzka-Rystwej P.   +5 more
europepmc   +4 more sources

Characterisation of Lagovirus europaeus GI-RHDVs (Rabbit Haemorrhagic Disease Viruses) in Terms of Their Pathogenicity and Immunogenicity. [PDF]

Int J Mol Sci
Rabbit haemorrhagic disease viruses (RHDV) belong to the family Caliciviridae, genus Lagovirus europaeus, genogroup GI, comprising four genotypes GI.1–GI.4, of which the genotypes GI.1 and GI.2 are pathogenic RHD viruses, while the genotypes GI.3 ...
Tokarz-Deptuła B, Kulus J, Baraniecki Ł, Stosik M, Deptuła W.   +4 more
europepmc   +4 more sources

MicroRNAs Regulate the Expression of Genes Related to the Innate Immune and Inflammatory Response in Rabbits Infected with Lagovirus europaeus GI.1 and GI.2 Genotypes. [PDF]

Int J Mol Sci
MicroRNAs (miR) are a group of small, non-coding RNAs of 17–25 nucleotides that regulate gene expression at the post-transcriptional level. Dysregulation of miRNA expression or function may contribute to abnormal gene expression and signaling ...
Ostrycharz-Jasek E, Fitzner A, Siennicka A, Budkowska M, Hukowska-Szematowicz B.   +4 more
europepmc   +4 more sources

Etiology of viral induced acute liver failure and defensins as potential therapeutic agents in ALF treatment [PDF]

Frontiers in Immunology, 2023
Acute liver failure (ALF) is a rare and severe disease, which, despite continuous advances in medicine, is still characterized by high mortality (65-85%). Very often, a liver transplant is the only effective treatment for ALF.
Rafał Hrynkiewicz, Paulina Niedźwiedzka-Rystwej   +1 more
doaj   +2 more sources

Pathological and virological insights from an outbreak of European brown hare syndrome in the Italian hare (Lepus corsicanus) [PDF]

Frontiers in Microbiology, 2023
European brown hare syndrome (EBHS) is a highly contagious and fatal viral disease, mainly affecting European brown hares (Lepus europaeus). The etiological agent, EBHS virus (EBHSV), belongs to the Lagovirus genus within the Caliciviridae family.
Mariagiovanna Domanico, Patrizia Cavadini, Roberto Nardini, Daniele Cecca, Giovanni Mastrandrea, Claudia Eleni, Valentina Galietta, Lorenzo Attili, Antonella Pizzarelli, Roberta Onorati, Cristina Amoruso, Donatella Stilli, Giulia Pacchiarotti, Francesca Merzoni, Andrea Caprioli, Ida Ricci, Antonio Battisti, Antonio Lavazza, Maria Teresa Scicluna   +18 more
doaj   +2 more sources

Lagovirus europaeus GI.2/RHDV2 (Rabbit Haemorrhagic Disease Virus 2) [PDF]

, 2018
Rabbit haemorrhagic disease (RHD) was first detected in 1984 and quickly spread among wild and domestic European rabbits (Oryctolagus cuniculus) throughout the world.
Neimanis, Aleksija
core   +3 more sources