Results 31 to 40 of about 227 (88)

Characterisation of Lagovirus europaeus GI-RHDVs (Rabbit Haemorrhagic Disease Viruses) in Terms of Their Pathogenicity and Immunogenicity. [PDF]

Int J Mol Sci
Rabbit haemorrhagic disease viruses (RHDV) belong to the family Caliciviridae, genus Lagovirus europaeus, genogroup GI, comprising four genotypes GI.1–GI.4, of which the genotypes GI.1 and GI.2 are pathogenic RHD viruses, while the genotypes GI.3 and GI.4 are non-pathogenic RCV (Rabbit calicivirus) viruses.
Tokarz-Deptuła B, Kulus J, Baraniecki Ł, Stosik M, Deptuła W.   +4 more
europepmc   +3 more sources

Immune response in the recombinant strain of Lagovirus europaeus GI.1a

Infection, Genetics and Evolution, 2023
Lagovirus europaeus/GI.1 is the virus that causes severe and dangerous rabbit haemorrhagic disease (RHD) in rabbits. Recombination formation in RHD viruses is common. Recombination is thought to play a key role in the evolution of lagoviruses and therefore most likely influences the pathogenicity of L. europaeus/GI strains.
Dominika, Bębnowska, Rafał, Hrynkiewicz, Izabela, Korona-Głowniak, Paulina, Niedźwiedzka-Rystwej   +3 more
openaire   +2 more sources

Apoptotic Cell Death in an Animal Model of Virus-Induced Acute Liver Failure-Observations during Lagovirus europaeus/GI.2 Infection. [PDF]

Int J Mol Sci
Lagovirus europaeus/GI.2 causes severe and highly fatal Rabbit Hemorrhagic Disease (RHD). Because of its characteristics, this infection is used as an animal model for acute liver failure (ALF). Apoptosis is one of the key processes underlying ALF and has been described as one of the mechanisms of RHD pathogenesis.
Bębnowska D, Hrynkiewicz R, Rzeszotek S, Freus M, Poniewierska-Baran A, Niedźwiedzka-Rystwej P.   +5 more
europepmc   +3 more sources

Widespread occurrence of the non‐pathogenic hare calicivirus (HaCV Lagovirus GII.2) in captive‐reared and free‐living wild hares in Europe

Transboundary and Emerging Diseases, Volume 68, Issue 2, Page 509-518, March 2021., 2021
Abstract The Lagovirus genus comprises both pathogenic viruses as European brown hare syndrome virus (EBHSV‐ GII.1) and rabbit hemorrhagic disease viruses (RHDV‐GI.1 and RHDV2‐GI.2), that principally infect European brown hares (Lepus europeaus) and European rabbits (Oryctolagus cuniculus), respectively, causing severe necrotic hepatitis, spleen ...
Patrizia Cavadini, Stefano Molinari, Francesca Merzoni, Alice Vismarra, Annika Posautz, Vanesa Alzaga Gil, Mario Chiari, Francesca Giannini, Lorenzo Capucci, Antonio Lavazza   +9 more
wiley   +1 more source

MicroRNAs Regulate the Expression of Genes Related to the Innate Immune and Inflammatory Response in Rabbits Infected with Lagovirus europaeus GI.1 and GI.2 Genotypes. [PDF]

Int J Mol Sci
MicroRNAs (miR) are a group of small, non-coding RNAs of 17–25 nucleotides that regulate gene expression at the post-transcriptional level. Dysregulation of miRNA expression or function may contribute to abnormal gene expression and signaling pathways, leading to disease pathology. Lagovirus europaeus (L.
Ostrycharz-Jasek E, Fitzner A, Siennicka A, Budkowska M, Hukowska-Szematowicz B.   +4 more
europepmc   +3 more sources

The Interplay between Autophagy and Virus Pathogenesis—The Significance of Autophagy in Viral Hepatitis and Viral Hemorrhagic Fevers

Cells, 2022
Autophagy is a process focused on maintaining the homeostasis of organisms; nevertheless, the role of this process has also been widely documented in viral infections. Thus, xenophagy is a selective form of autophagy targeting viruses.
Dominika Bębnowska, Paulina Niedźwiedzka-Rystwej   +1 more
doaj   +1 more source

Genetic diversity and evolution of Hare Calicivirus (HaCV), a recently identified lagovirus from Lepus europaeus

Infection, Genetics and Evolution, 2020
First recognized as highly pathogenic viruses, hare lagoviruses belonging to genotype GII.1 (EBHSV) infect various Lepus species. Genetically distinct benign lagoviruses (Hare Calicivirus, HaCV) have recently been identified but few data have been available so far on these strains.
Droillard, Clément, Lemaitre, Evelyne, Chatel, Marina, Quéméner, Agnès, Briand, François-Xavier, Guitton, Jean-Sébastien, Marchandeau, Stéphane, Le Pendu, Jacques, Eterradossi, Nicolas, Le Gall-Reculé, Ghislaine   +9 more
openaire   +5 more sources

RHDV2 epidemic in UK pet rabbits. Part 1: clinical features, gross post mortem and histopathological findings

Journal of Small Animal Practice, Volume 61, Issue 7, Page 419-427, July 2020., 2020
Objectives To report clinical features, gross post mortem and histopathological findings from an investigation into sudden or unexpected death in rabbits that was undertaken during an outbreak of rabbit haemorrhagic disease. Materials and Methods Using a standard protocol, veterinarians were invited to submit case histories and results of their post ...
N. Harcourt‐Brown, M. Silkstone, T. J. Whitbread, F. M. Harcourt‐Brown   +3 more
wiley   +1 more source

European Brown Hare Syndrome in Poland: Current Epidemiological Situation

Viruses, 2022
European brown hare syndrome (EBHS) is one of the main causes of mortality in brown hares (Lepus europaeus) and mountain hares (Lepus timidus) in Europe.
Andrzej Fitzner, Wiesław Niedbalski, Andrzej Kęsy, Bogusław Rataj, Marian Flis   +4 more
doaj   +1 more source

Relationship between Anti‐European Brown Hare Syndrome Serological Titers and Brown Hare (Lepus europaeus Pallas) Densities

International Journal of Zoology, Volume 2011, Issue 1, 2011., 2011
Thirty‐three protected wild game reproduction areas, located in the province of Florence (Central Italy), were monitored for habitat characteristics and hare census over a period of 2 years. A total of 172 hares was captured, checked for sex, and age, and blood samples were taken.
Gisella Paci, Antonio Lavazza, Marco Ferretti, Francesco Santilli, Marco Bagliacca, Frank Seebacher   +5 more
wiley   +1 more source