Results 31 to 40 of about 3,493 (205)

The effect of live attenuated influenza vaccine on pneumococcal colonisation densities among children aged 24–59 months in The Gambia: a phase 4, open label, randomised, controlled trial

open access: yesThe Lancet Microbe, 2021
Summary: Background: Influenza and other respiratory viruses promote Streptococcus pneumoniae proliferation in the upper respiratory tract. We sought to investigate for what we believe is the first time, the effect of intranasal live attenuated ...
Chikondi Peno, MSc   +17 more
doaj   +1 more source

A Bivalent Live-Attenuated Vaccine for the Prevention of Equine Influenza Virus

open access: yesViruses, 2019
Vaccination remains the most effective approach for preventing and controlling equine influenza virus (EIV) in horses. However, the ongoing evolution of EIV has increased the genetic and antigenic differences between currently available vaccines and ...
Pilar Blanco-Lobo   +7 more
doaj   +1 more source

A New Master Donor Virus for the Development of Live-Attenuated Influenza B Virus Vaccines

open access: yesViruses, 2021
Influenza B viruses (IBV) circulate annually, with young children, the elderly and immunocompromised individuals being at high risk. Yearly vaccinations are recommended to protect against seasonally influenza viruses, including IBV.
Chantelle L. White   +6 more
doaj   +1 more source

Immunogenicity and protective efficacy of prime-boost immunization in mice vaccinated with live and inactivated influenza A (H5N1) vaccines

open access: yesИнфекция и иммунитет, 2019
Avian influenza A (H1N1) in humans is characterized by severe clinical manifestation and high mortality. The main drawback of current human H5N1 vaccines is related to low immunogenicity.
I. Losev   +3 more
doaj   +1 more source

Increasing the Safety Profile of the Master Donor Live Attenuated Influenza Vaccine

open access: yesPathogens, 2020
Seasonal influenza epidemics remain one of the largest public health burdens nowadays. The best and most effective strategy to date in preventing influenza infection is a worldwide vaccination campaign. Currently, two vaccines are available to the public
Thomas A. Hilimire   +4 more
doaj   +1 more source

Demonstrating the capacity of the National Advisory Committee on Immunization for timely responses to post-market vaccine monitoring signals: Canada’s experience with the live-attenuated influenza vaccine

open access: yesCanada Communicable Disease Report, 2021
Over the last several years, the recommended use of the live-attenuated influenza vaccine (LAIV) for children has evolved in the United States (US) in response to evidence of a potential decrease in LAIV effectiveness based on post-market monitoring ...
Linlu Zhao   +4 more
doaj   +1 more source

Live Attenuated Influenza Vaccine (LAIV) Immunization in Children and Adults: Lesson for Development of Universal Influenza Vaccine [PDF]

open access: yes, 2019
According to the WHO (World Health Organization), one billion peoples are infected annually of whom three to five millions become severely ill and 250-500 000 deaths worldwide (He, Wang et al.
Islam, Shahinul
core   +1 more source

Sequential Immunization With Live-Attenuated Chimeric Hemagglutinin-Based Vaccines Confers Heterosubtypic Immunity Against Influenza A Viruses in a Preclinical Ferret Model

open access: yesFrontiers in Immunology, 2019
Due to continuous antigenic drift and occasional antigenic shift, influenza viruses escape from human adaptive immunity resulting in significant morbidity and mortality in humans. Therefore, to avoid the need for annual reformulation and readministration
Wen-Chun Liu   +13 more
doaj   +1 more source

Pneumococcal colonization impairs mucosal immune responses to live attenuated influenza vaccine

open access: yesJCI Insight, 2021
Influenza virus infections affect millions of people annually, and current available vaccines provide varying rates of protection. However, the way in which the nasal microbiota, particularly established pneumococcal colonization, shape the response to ...
Beatriz F. Carniel   +17 more
doaj   +1 more source

664Influenza Vaccination in Chronically Ill Children: Taking a Closer Look at LAIV [PDF]

open access: yesOpen Forum Infectious Diseases, 2014
(1)Division of Infectious Diseases; Department of Pediatrics, The Montreal Children's Hospital, Montreal, QC, Canada, (2) Ministere de la Sante et des Services Sociaux du Quebec, Montreal, QC, Canada, (3)Vaccine Study Centre, Research Institute of the McGill Univ.
Merckx, Joanna   +4 more
openaire   +1 more source

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