Results 61 to 70 of about 3,493 (205)

Evaluating α-galactosylceramide as an adjuvant for live attenuated influenza vaccines in pigs

Animal Diseases, 2022
Natural killer T (NKT) cells activated with the glycolipid ligand α-galactosylceramide (α-GalCer) stimulate a wide variety of immune cells that enhance vaccine-mediated immune responses. Several studies have used this approach to adjuvant inactivated and
Bianca L. Artiaga, Igor Morozov, Russell Ransburgh, Taeyong Kwon, Velmurugan Balaraman, Sabarish V. Indran, Darling Melany De Carvalho Madrid, Weihong Gu, Jamie Henningson, Wenjun Ma, Jürgen A. Richt, John P. Driver   +11 more
doaj   +1 more source

A Mutated PB1 Residue 319 Synergizes with the PB2 N265S Mutation of the Live Attenuated Influenza Vaccine to Convey Temperature Sensitivity

Viruses, 2020
Current influenza vaccines have modest efficacy. This is especially true for current live attenuated influenza vaccines (LAIV), which have been inferior to the inactivated versions in recent years.
Andrew Cox, Jordana Schmierer, Josephine D’Angelo, Andrew Smith, Dustyn Levenson, John Treanor, Baek Kim, Stephen Dewhurst   +7 more
doaj   +1 more source

Human Immune Response to Influenza Neuraminidase After Vaccination: A Systematic Review

Influenza and Other Respiratory Viruses, Volume 19, Issue 12, December 2025.
ABSTRACTBackgroundLicensed influenza vaccines primarily target hemagglutinin (HA)‐related immunity, but neuraminidase (NA)‐based immunity is gaining attention as an independent correlate of protection. Inactivated influenza vaccines contain unspecified quantities of residual NA, with limited understanding of the resulting antibody induction and ...
Vardhini Ganesh, Justin Iampietro, Saranya Sridhar, Ana P. Goncalvez   +3 more
wiley   +1 more source

Safety and immunogenicity following administration of a live, attenuated monovalent 2009 H1N1 influenza vaccine to children and adults in two randomized controlled trials. [PDF]

PLoS ONE, 2010
The safety, tolerability, and immunogenicity of a monovalent intranasal 2009 A/H1N1 live attenuated influenza vaccine (LAIV) were evaluated in children and adults.Two randomized, double-blind, placebo-controlled studies were completed in children (2-17 y)
Raburn M Mallory, Elissa Malkin, Christopher S Ambrose, Terramika Bellamy, Li Shi, Tingting Yi, Taff Jones, George Kemble, Filip Dubovsky   +8 more
doaj   +1 more source

Effectiveness of Influenza Vaccines and Duration of Protection Against Hospitalisation in England: 2022/2023 and 2023/2024 Seasons

Influenza and Other Respiratory Viruses, Volume 19, Issue 12, December 2025.
ABSTRACT Background Linkage of national, healthcare data can provide greater resolution of vaccine effectiveness (VE) against influenza subtypes, as well as the relative effectiveness of different vaccine types and the effects of waning on VE. We present 2022/2023 and 2023/2024 end‐of‐season VE against hospitalisation with laboratory confirmed ...
Heather J. Whitaker, Freja C. M. Kirsebom, Katie Hassell, Catherine Quinot, Julia Stowe, Katja Hoschler, Maria Zambon, Nick J. Andrews, Conall H. Watson, Jamie Lopez Bernal   +9 more
wiley   +1 more source

985. Safety of Guidelines Recommending LAIV for Routine Use in Children and Adolescents With Asthma [PDF]

Open Forum Infectious Diseases, 2018
Abstract Background Asthma is the most common chronic medical condition in children. Prior observational studies of live attenuated influenza vaccine (LAIV) safety in asthmatic children have been limited due to confounding by indication, with LAIV restricted to patients with mild asthma.
Nordin, James, Vazquez-Benitez, Gabriela, Olsen, Avalow, Kuckler, Leslie, Kharbanda, Elyse   +4 more
openaire   +1 more source

Estimated Relative Effectiveness and Public Health Impact of Cell‐Based Versus Egg‐Based Influenza Vaccines During the 2022–2023 Season in the United States

Influenza and Other Respiratory Viruses, Volume 19, Issue 11, November 2025.
ABSTRACT Background Egg adaptation can reduce the effectiveness of egg‐based influenza vaccines. Previous studies have demonstrated improved effectiveness of cell versus egg‐based quadrivalent influenza vaccines (QIVc and QIVe, respectively) during the 2017–2020 influenza seasons among persons aged ≥ 4 years.
Alicia N. Stein, Anusorn Thanataveerat, Kimberly W. McDermott, Alex Dean, Stephanie Wall, Cory Pack, Sheena G. Sullivan, Ian McGovern, Mendel D. M. Haag   +8 more
wiley   +1 more source

CD4+ tissue‐resident memory T cells and their role in immunity

Immunology &Cell Biology, Volume 103, Issue 8, Page 809-819, September 2025.
In this article, we review and discuss the role of CD4+ tissue‐resident memory T (TRM) cells and their role in immune protection in tissues, such as the lungs, by facilitating pathogen clearance through cytokine production and local immune interactions.
Margarida Kirkby, Marc Veldhoen
wiley   +1 more source

Valorización de Laive S.A.

, 2020
Con el presente trabajo, buscamos obtener el valor fundamental de la acción de la empresa Laive al cierre del año 2018 a través de los métodos de flujo de caja descontado y dividendos descontados, aprendidos en la Maestría en Finanzas. Laive se dedica principalmente a la elaboración, producción y comercialización de lácteos y sus derivados que, al ...
Carrasco Montero, Claudia Marilia, Castillo Quispe, David Israel, Valer Gómez, Jesús Rodrigo   +2 more
openaire   +1 more source

rNP cross-reactivity among LAIV, XSV and SEOV.

, 2019
Western blot was used to characterize the reactivity of (A) prokaryotically expressed rNPs by SEOV-convalescent human serum (H anti-SEOV) and negative human serum (H Neg.), and (B) eukaryotically expressed rNPs by three specific anti-rNP hyperimmune sera
Yamei Wei (3149352), Xiaohong Huang (222480), Fuqiang Zhang (404974), Jianmin Wu (19537), Zhizhou Tan (6250940), Huancheng Guo (404972), Ling’en Yang (6250946), Biao He (1833), Lin Xu (94491), Qi Li (67548), Changchun Tu (404976), Jianqiu Cai (6250943), Jing Chen (4762)   +12 more
core   +1 more source