Results 41 to 50 of about 4,323 (166)

Concurrent Paraneoplastic Neuromyelitis Optica and Lambert-Eaton Myasthenic Syndrome

, 2023
Lambert-Eaton Myasthenic Syndrome (LEMS) is uncommon and associated with small cell lung cancer (SCLC). Neuromyelitis optica spectrum disorder (NMOSD) is rare, and has also been reported in association with malignancy, most commonly, breast ...
Haley D\u27Souza; M. Tariq Bhatti; Andrew McKeon; John Chen; Deena Tajfirouz
core  

Recurrent Steroid‐Responsive Exophthalmos as a Paraneoplastic Manifestation of Esophageal Adenocarcinoma

Case Reports in Oncological Medicine, Volume 2026, Issue 1, 2026.
Exophthalmos is most often associated with autoimmune thyroid disease, particularly Graves disease. Paraneoplastic syndromes rarely manifest as orbital inflammation, and only a few cases have been described in association with solid tumors. We present a case of a 67‐year‐old male diagnosed with esophageal cancer.
Yara E. Tovar, Ahmed G. Elsayed, Lipi Buch   +2 more
wiley   +1 more source

Retinal glycoprotein enrichment by concanavalin a enabled identification of novel membrane autoantigen synaptotagmin-1 in equine recurrent uveitis. [PDF]

, 2012
Complete knowledge of autoantigen spectra is crucial for understanding pathomechanisms of autoimmune diseases like equine recurrent uveitis (ERU), a spontaneous model for human autoimmune uveitis. While several ERU autoantigens were identified previously,
Cornelia A. Deeg, Amann, B., Naim, Hassan Y., Amann, Barbara, Hauck Stefanie M., Barbara Amann, Hassan Y. Naim, Swadzba Margarete E., Naim, H.Y., Naim Hassan Y., Hauck, S.M., Cornelia A Deeg, Swadzba, Margarete E., Margarete E. Swadzba, Deeg Cornelia A., Amann Barbara, Stefanie M Hauck, Stefanie M. Hauck, Hassan Y Naim, Deeg, Cornelia A., Hauck, Stefanie M., Margarete E Swadzba, Deeg, C.A., Swadzba, M.E.   +23 more
core   +1 more source

Update on treatment options for Lambert–Eaton myasthenic syndrome: focus on use of amifampridine

Neuropsychiatric Disease and Treatment, 2011
Sabine Lindquist, Martin StangelSection Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, Hannover, GermanyAbstract: In Lambert–Eaton myasthenic syndrome (LEMS), antibodies against presynaptic ...
Lindquist S, Stangel M
doaj  

Gender issues of antibody-mediated diseases in neurology: (NMOSD/autoimmune encephalitis/MG)

Therapeutic Advances in Neurological Disorders, 2020
Neuromyelitis optica spectrum disorder (NMOSD), autoimmune encephalitis (AE), myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) are antibody-mediated neurological diseases.
Ayse Altintas, Justina Dargvainiene, Christiane Schneider-Gold, Nasrin Asgari, Ilya Ayzenberg, Andrea I. Ciplea, Ralf Junker, Frank Leypoldt, Klaus-Peter Wandinger, Kerstin Hellwig   +9 more
doaj   +1 more source

MGBase: A Global, Observational Registry for Collaborative Research in Myasthenia Gravis

Muscle &Nerve, Volume 72, Issue 3, Page 424-432, September 2025.
ABSTRACT Introduction/Aims Patient registries are valuable tools for outcomes research in rare diseases such as myasthenia gravis (MG). Existing MG registries are limited by factors including a lack of geographical scope. MGBase has been designed as a global, observational registry aimed at studying clinical practice outcomes in MG.
Katherine A. Buzzard, Anneke Van der Walt, Helmut Butzkueven, Wen Wen Zhang, Carolina Barnett‐Tapia, Gary Cutter, Jeannine M. Heckmann, Pamela Farr, Carolyn Tran, Charlotte Sartori, Dusko Stupar, Rein More, Linda Sim, Alison Le, Qingxiao Tang, Stephen W. Reddel, the MGBase Study Group, Stefan Blum, Gabvor Lovas, Pamela McCombe, Elisabeth Chroni, Belinda Cruse, Raed Alroughani, John Tzartos, Enrique Gomex‐Figueroa, Cavit Boz, Guntis Karelis, Allan Kermode, Nicholas Crump   +28 more
wiley   +1 more source

Efficacy and Safety of Efgartigimod for Patients With Myasthenia Gravis in a Real‐World Cohort of 77 Patients

CNS Neuroscience &Therapeutics, Volume 31, Issue 4, April 2025.
This real‐world study of 77 myasthenia gravis (MG) patients treated with efgartigimod showed rapid symptom improvement across disease severities. Sustained efficacy was achieved with repeated cycles, positioning efgartigimod as a promising MG therapy combining swift response and durable maintenance benefits. ABSTRACT Aims Efgartigimod, a first‐in‐class
Sijia Hao, Zhe Ruan, Rongjing Guo, Qingqing Wang, Xiaoxi Huang, Chao Sun, Huanhuan Li, Ting Gao, Yonglan Tang, Xiangqi Cao, Yu Liu, Zhuyi Li, Ting Chang   +12 more
wiley   +1 more source

Myasthenia gravis and Lambert-Eaton myasthenic syndrome: treatment options and guidance for management during COVID-19 pandemic

Neurologijos seminarai, 2020
Myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) are immune-mediated neurologic disorders characterized by muscle weakness and fatigue. MG is the most common neuromuscular junction disorder while LEMS is an extraordinary rare disease.
A. Klimašauskienė , R. Bunevičiūtė
doaj   +1 more source

Cerebellar ataxia in non-paraneoplastic Lambert-Eaton myasthenic syndrome.

, 2008
Lambert-Eaton myasthenic syndrome (LEMS) is an immune-mediated disorder of the neuromuscular junction that rarely is associated with cerebellar ataxia (CA).
Scola, RH, Kay, CS, Kowacs, PA, Werneck, LC, Lang, Bethan, Teive, HA, Lang, B, Lorenzoni, PJ   +7 more
core   +1 more source

Clinical Features of Glutamic Acid Decarboxylase‐65 Neurological Autoimmunity: A Case Series From China

CNS Neuroscience &Therapeutics, Volume 31, Issue 2, February 2025.
The clinical spectrum of GAD65 autoimmune neurological diseases appeared highly diverse. Immunotherapy can benefit the majority of patients, and early treatment appeared to be associated with good prognosis. RTX may be more effective than MMF; however, this requires more rigorous prospective studies to explore.
Zhandong Qiu, Fang Xu, Mengyao Zhang, Xixi Yang, Yan Han, Dawei Li, Liang Liu, Jia Chen, Lehong Gao, Qing Xue, Yue Hou, Ying Sun, Li Di, Chunqiu Fan, Junhua Liang, Yue Han, Huiqing Dong, Junwei Hao, Zheng Liu   +18 more
wiley   +1 more source