Results 51 to 60 of about 4,323 (166)

Lamber-Eaton myasthenic syndrome associated with multiple myeloma: A case report

Current Problems in Cancer: Case Reports
Background: Lambert-Eaton myasthenic syndrome (LEMS) is an uncommon illness of the neuromuscular junction. It typically manifests as a combination of proximal muscular weakness, autonomic dysfunction, and areflexia.
Sebastian S Casillas-Berumen, Ahsan Salik, Alex Yu, Mageda Al Areqi, Ayesha Ali, Resham Mirza, Shaan Chaudhri, Gurpreet Lamba   +7 more
doaj   +1 more source

Anti-CV2/CRMP5 antibody-positive paraneoplastic neurological syndromes with chronic intestinal pseudo-obstruction in a small-cell lung cancer patient: a case report and literature review

Journal of International Medical Research, 2020
Patients with anti-CV2/collapsin response mediator protein (CRMP)5 antibodies present with more frequent chorea, cerebellar ataxia, uveo/retinal symptoms, and Lambert–Eaton myasthenic syndrome or myasthenia gravis.
Jinhua Yan, Zhongbo Chen, Yumei Liang, Huijia Yang, Lizhi Cao, Yuling Zhou, Yang Zhao, Ying Zhang   +7 more
doaj   +1 more source

Nanoflowers Templated CuO/Cu Hybrid Metasurface for Sensitive THz‐TDS Detection of Acetylcholine

Advanced Sensor Research, Volume 3, Issue 12, December 2024.
This research focuses on sensitively detecting acetylcholine in the terahertz range through the integration of CuO nanoflowers with Cu nanoslots. The terahertz transmittance measurements are recalibrated by incorporating acidic components hydrolyzed from acetylcholine.
Soo Hyun Lee, Taeyeon Kim, Minah Seo
wiley   +1 more source

Antibodies against the β subunit of voltage-dependent calcium channels in Lambert–Eaton Myasthenic Syndrome

, 1999
International audienceLambert-Eaton myasthenic syndrome is an autoimmune disease that impairs neuromuscular transmission. Several studies suggest that neurotransmitter release is reduced by an immune response directed against the calcium channel complex ...
M De Waard, Seagar, M, Raymond, C, Iborra, C, D Walker, Martin-Moutot, N, N Martin-Moutot, C Iborra, Bichet, D, C Raymond, Walker, D, de Waard, M, D Bichet, M Seagar   +13 more
core   +1 more source

SOX1 antibodies are markers of paraneoplastic Lambert-Eaton myasthenic syndrome [PDF]

, 2008
BACKGROUND/OBJECTIVE: We reported that 43% of patients with Lambert-Eaton myasthenic syndrome (LEMS) and small cell lung cancer (SCLC) had an antibody called anti-glial nuclear antibody (AGNA), defined by the immunoreaction with the nuclei of the ...
Saiz, A., Titulaer, M., Verschuuren, J., Güre, A. O., Graus, F., Sabater, L.   +5 more
core   +1 more source

Diaphragmatic Palsy Due to a Paraneoplastic Autoimmune Syndrome Revealed by Checkpoint Inhibitors

Reports
Background and Clinical Significance: Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment but may underlie diverse and potentially life-threatening immune-related adverse events (irAEs).
Jean-Baptiste Destival, Jean-Marie Michot, Cécile Cauquil, Nicolas Noël, Salima Hacein-Bey-Abina, Pascale Chrétien, Olivier Lambotte   +6 more
doaj   +1 more source

Paraneoplastic neurological syndrome and its impact on the treatment outcomes of small‐cell lung cancer: A single‐center retrospective analysis

Thoracic Cancer, Volume 15, Issue 34, Page 2418-2427, December 2024.
Patients diagnosed with small‐cell lung cancer (SCLC) at a single center between August 2007 and April 2021 were retrospectively analyzed. A total of 318 patients were evaluated; paraneoplastic neurological syndrome (PNS) was present in 2.8% (n = 9) of the overall population.
Yuki Sato, Satoru Fujiwara, Chigusa Shirakawa, Ryosuke Hirabayashi, Kazuma Nagata, Atsushi Nakagawa, Ryo Tachikawa, Keisuke Tomii   +7 more
wiley   +1 more source

Pseudomyopathic Changes in Needle Electromyography in Lambert-Eaton Myasthenic Syndrome

Case Reports in Neurological Medicine, 2013
Lambert-Eaton myasthenic syndrome (LEMS) is a rare presynaptic disorder of the neuromuscular junction in association with cancer and subsequently in cases in which no neoplasm has been detected (O’Neill et al., 1988).
Teppei Komatsu, Kota Bokuda, Toshio Shimizu, Tetsuo Komori, Reiji Koide   +4 more
doaj   +1 more source

Antibodies against endogenous retroviruses

Immunological Reviews, Volume 328, Issue 1, Page 300-313, November 2024.
Summary The human genome harbors hundreds of thousands of integrations of ancient retroviruses, amassed over millions of years of evolution. To reduce further amplification in the genome, the host prevents transcription of these now endogenous retroviruses (ERVs) through epigenetic repression and, with evolutionary time, ERVs are incapacitated by ...
Mihaela Chisca, Jean‐David Larouche, Qi Xing, George Kassiotis   +3 more
wiley   +1 more source

The impact of diagnosis delay on European patients with generalised myasthenia gravis

Annals of Clinical and Translational Neurology, Volume 11, Issue 9, Page 2254-2267, September 2024.
Abstract Objective The objective was to determine the mean duration of diagnosis delay for patients with myasthenia gravis from five European countries and explore the impact of >1 year diagnosis delay. Methods Patients with myasthenia gravis (N = 387) from Europe (France/Germany/Italy/Spain/United Kingdom) and their physicians participated in the ...
Elena Cortés‐Vicente, Andras J. Borsi, Charlotte Gary, Wim G.J. Noel, Jennifer M.S. Lee, Wisam Karmous, Qiaoyi Zhang, Kavita H. Gandhi, Alberto E. Batista, Jonathan J. DeCourcy, Sophie G. Barlow, Shiva L. Birija, Gregor A. Gibson   +12 more
wiley   +1 more source