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Thoracic Cancer, Volume 15, Issue 17, Page 1350-1356, June 2024.In a retrospective study, serum from patients with biopsy‐proven small‐cell lung cancer (SCLC) at the time of diagnosis was studied prior to treatment. The sera were analyzed for the presence of neuronal autoantibodies blinded to clinical status. The main finding was demonstration that neuronal autoantibodies were frequent at the time of diagnosis ...
Anne With Mikkelsen +4 more
wiley +1 more source
Patient perspectives on Lambert-Eaton myasthenic syndrome
To better understand what it\u27s like to live with Lambert-Eaton myasthenic syndrome (LEMS), we spoke to two individuals who have been living with non-tumor LEMS for years.
Randall, David P +5 more
core +1 more source
Type 2 fiber predominance in Lambert-Eaton myasthenic syndrome.
, 1991 Serial muscle biopsies in a noncarcinomatous case of Lambert-Eaton myasthenic syndrome (LEMS) have shown progressive atrophy and loss of type 1 fibers, resulting in overwhelming type 2 predominance. A similar abnormality was found in a single biopsy from
Hilton-Jones, David +5 more
core +1 more source
Chinese Journal of Cancer, 2016 Lambert–Eaton myasthenic syndrome (LEMS) is a paraneoplastic syndrome and only 3% of small cell lung carcinoma (SCLC) patients have LEMS. Moreover, the recurrence of SCLC after a disease-free survival (DFS) of more than 10 years is rare.
Fumio Asano +10 more
doaj +1 more source
Idiopathic Lambert-Eaton myasthenic syndrome. Report of one case [PDF]
, 2006 Lambert-Eaton myasthenic syndrome (LEMS) is an autoinmune idiopathic or paraneoplastic syndrome producing antibodies agaisnt presynaptic voltage calcium channels.
Idiáquez C., Juan +3 more
core
Transient Lambert-Eaton myasthenic syndrome associated with systemic lupus erythematosus [PDF]
, 1989 We present a patient who developed the Lambert–Eaton myasthenic syndrome (LEMS) in association with systemic lupus erythematosus (SLE). Severe proximal weakness with electrodiagnostic evidence of LEMS developed over 2 days during an exacerbation of ...
Albers, James W. +2 more
core +1 more source
Electrophysiological and muscle pathological characteristics of Lambert - Eaton myasthenic syndrome
Chinese Journal of Contemporary Neurology and NeurosurgeryObjective To summarize the electrophysiological and muscle pathological characteristics of Lambert - Eaton myasthenic syndrome (LEMS). Methods and Results Twelve LEMS patients referred to China - Japan Friendship Hospital between January 2010 and ...
SUN Qing +5 more
doaj +1 more source
Lambert-Eaton myasthenic syndrome associated with intravascular uterine leiomyoma.
, 2011 Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune neurologic disease with impaired transmission across neuromuscular junction, and . LEMS is thought to be caused by antibodies directed against presynaptic P/Q-type voltage-gated calcium channels ...
Ariatti A +3 more
core +1 more source
Diagnosis and treatment of paraneoplastic neurological disorders [PDF]
, 2004 In about two thirds of cases, patients with paraneoplastic neurological disorders present to the neurologist without a known tumor. Due to the ongoing immune response, this tumor tends to stay biologically relatively benign, and therefore difficult to ...
Voltz, R., Graus, F.
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Lambert-Eaton myasthenic syndrome – a misdiagnosed condition [PDF]
, 2019 Background: Lambert-Eaton myasthenic syndrome (LEMS) is a rare disorder of the neuromuscular junction. Clinical features include proximal muscle weakness, markedly in the lower limbs, reduced deep tendon reflexes that can increase after exercise, and ...
Sangheli, Marina +5 more
core +1 more source