Results 81 to 90 of about 4,323 (166)
Autoantibodies in neuromuscular disorders: a review of their utility in clinical practice
A great proportion of neuromuscular diseases are immune-mediated, included myasthenia gravis, Lambert-Eaton myasthenic syndrome, acute- and chronic-onset autoimmune neuropathies (anti-MAG neuropathy, multifocal motor neuropathy, Guillain-Barré syndromes,
Valentin Loser +2 more
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Lambert-Eaton myasthenic syndrome (LEMS) is a rare, autoimmune or paraneoplastic condition characterized by muscle weakness and fatigability. In cancer therapy, immune checkpoint inhibitors (ICI) sensitize the immune system for tumor antigens.
Maike F. Dohrn +6 more
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Lambert-Eaton Myasthenia Syndrome Initial Presentation Mimicking Myasthenia Gravis
The neuromuscular junction disorders myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) both present with muscle weakness but usually have clinical features that distinguish the 2 disorders (1-3)
S. Y. Uhm; H. Nguyen; K. P. Kanakia; J. E. Carter
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Non-paraneoplastic Lambert-Eaton myasthenic syndrome: a brief review of 10 cases
Lambert-Eaton myasthenic syndrome (LEMS) is an immune-mediated disorder of the presynaptic neuromuscular transmission, which more frequently occurs as the remote effect of a neoplasm, in the paraneoplastic form (P-LEMS), or in a non-paraneoplastic form ...
Paulo J. Lorenzoni +4 more
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The Lambert-Eaton Myasthenic Syndrome
The Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disease of the neuromuscular junction. The main symptom in LEMS is proximal muscle weakness in the legs, which is the presenting symptom in most patients. Autonomic dysfunction is also part of
Maarten J. Titulaer +5 more
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Electrophysiological study in neuromuscular junction disorders
This review is on ultrastructure and subcellular physiology at normal and abnormal neuromuscular junctions. The clinical and electrophysiological findings in myasthenia gravis, Lambert-Eaton myasthenic syndrome (LEMS), congenital myasthenic syndromes ...
Ajith Cherian +2 more
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Neuromuscular junction disorders affect the pre- or postsynaptic nerve to muscle transmission due to autoimmune antibodies. Members of the group like myasthenia gravis and Lambert-Eaton syndrome have pathophysiologically distinct characteristics. However,
Andreas Totzeck +3 more
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Bilateral ptosisA 15-month old male developed droopy eyelids the day he suffered minor head trauma. Subsequently, over a 2-week period lethargy and fatigue were manifest.A neurological exam, Tensilon and neostigmine tests, and EMG\u27s were reported to ...
Mark J. Kupersmith, MD; R. Reuben; M. Gelwan, M. A. Greco; D. Ma; F. Warren
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We describe a patient affected by the Lambert-Eaton myasthenic syndrome, sensory motor axonal neuropathy and epidermoid carcinoma of the lung. Serum autoantibodies to voltage-operated calcium channels were detected.
M. Comola +8 more
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Autoantibodies to different subtypes of the voltage-gated calcium channel (VGCC) have been described in two very different neurological syndromes, the Lambert-Eaton myasthenic syndrome (LEMS) and amyotrophic lateral sclerosis (ALS).
Maddison, P +4 more
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