Results 81 to 90 of about 4,323 (166)

Autoantibodies in neuromuscular disorders: a review of their utility in clinical practice

open access: yesFrontiers in Neurology
A great proportion of neuromuscular diseases are immune-mediated, included myasthenia gravis, Lambert-Eaton myasthenic syndrome, acute- and chronic-onset autoimmune neuropathies (anti-MAG neuropathy, multifocal motor neuropathy, Guillain-Barré syndromes,
Valentin Loser   +2 more
doaj   +1 more source

Immunoglobulins to mitigate paraneoplastic Lambert Eaton Myasthenic Syndrome under checkpoint inhibition in Merkel cell carcinoma

open access: yesNeurological Research and Practice, 2020
Lambert-Eaton myasthenic syndrome (LEMS) is a rare, autoimmune or paraneoplastic condition characterized by muscle weakness and fatigability. In cancer therapy, immune checkpoint inhibitors (ICI) sensitize the immune system for tumor antigens.
Maike F. Dohrn   +6 more
doaj   +1 more source

Lambert-Eaton Myasthenia Syndrome Initial Presentation Mimicking Myasthenia Gravis

open access: yes, 2023
The neuromuscular junction disorders myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) both present with muscle weakness but usually have clinical features that distinguish the 2 disorders (1-3)
S. Y. Uhm; H. Nguyen; K. P. Kanakia; J. E. Carter
core  

Non-paraneoplastic Lambert-Eaton myasthenic syndrome: a brief review of 10 cases

open access: yesArquivos de Neuro-Psiquiatria, 2010
Lambert-Eaton myasthenic syndrome (LEMS) is an immune-mediated disorder of the presynaptic neuromuscular transmission, which more frequently occurs as the remote effect of a neoplasm, in the paraneoplastic form (P-LEMS), or in a non-paraneoplastic form ...
Paulo J. Lorenzoni   +4 more
doaj   +1 more source

The Lambert-Eaton Myasthenic Syndrome

open access: yes, 2013
The Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disease of the neuromuscular junction. The main symptom in LEMS is proximal muscle weakness in the legs, which is the presenting symptom in most patients. Autonomic dysfunction is also part of
Maarten J. Titulaer   +5 more
core   +1 more source

Electrophysiological study in neuromuscular junction disorders

open access: yesAnnals of Indian Academy of Neurology, 2013
This review is on ultrastructure and subcellular physiology at normal and abnormal neuromuscular junctions. The clinical and electrophysiological findings in myasthenia gravis, Lambert-Eaton myasthenic syndrome (LEMS), congenital myasthenic syndromes ...
Ajith Cherian   +2 more
doaj   +1 more source

Clinical features of neuromuscular disorders in patients with N-type voltage-gated calcium channel antibodies

open access: yesEuropean Journal of Translational Myology, 2016
Neuromuscular junction disorders affect the pre- or postsynaptic nerve to muscle transmission due to autoimmune antibodies. Members of the group like myasthenia gravis and Lambert-Eaton syndrome have pathophysiologically distinct characteristics. However,
Andreas Totzeck   +3 more
doaj   +1 more source

An Ocular Myasthenic Syndrome

open access: yes, 1987
Bilateral ptosisA 15-month old male developed droopy eyelids the day he suffered minor head trauma. Subsequently, over a 2-week period lethargy and fatigue were manifest.A neurological exam, Tensilon and neostigmine tests, and EMG\u27s were reported to ...
Mark J. Kupersmith, MD; R. Reuben; M. Gelwan, M. A. Greco; D. Ma; F. Warren
core  

Lambert-Eaton myasthenic syndrome and polyneuropathy in a patient with epidermoid carcinoma of the lung

open access: yes, 1993
We describe a patient affected by the Lambert-Eaton myasthenic syndrome, sensory motor axonal neuropathy and epidermoid carcinoma of the lung. Serum autoantibodies to voltage-operated calcium channels were detected.
M. Comola   +8 more
core   +1 more source

Autoantibodies in the Lambert-Eaton Myasthenic Syndrome (LEMS) and Amyotrophic Lateral Sclerosis (ALS)

open access: yes, 2013
Autoantibodies to different subtypes of the voltage-gated calcium channel (VGCC) have been described in two very different neurological syndromes, the Lambert-Eaton myasthenic syndrome (LEMS) and amyotrophic lateral sclerosis (ALS).
Maddison, P   +4 more
core   +1 more source

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