Results 231 to 240 of about 21,188,703 (341)

Amphibian oocyte nuclei expressing lamin A with the progeria mutation E145K exhibit an increased elastic modulus

, 2011
Anna Kaufmann, Fabian Heinemann, Manfred Radmacher, Reimer Stick   +3 more
openalex   +1 more source

Elevated Serum C-Reactive Protein and Free Fatty Acids Among Nondiabetic Carriers of Missense Mutations in the Gene Encoding Lamin A/C ( LMNA ) With Partial Lipodystrophy [PDF]

, 2003
Robert A. Hegele, Maria E. Kraw, Matthew R. Ban, Brooke A. Miskie, Murray W. Huff, Henian Cao   +5 more
openalex   +1 more source

Why and How Are Infants with Hutchinson-Gilford Progeria Syndrome Born Without Severe Manifestations? [PDF]

Med Sci (Basel)
Erokhina MA, Vorotelyak EA, Vasiliev AV, Abdyev VK.   +3 more
europepmc   +1 more source

Astrocyte Senescence Impairs Synaptogenesis due to Thrombospondin‐1 Loss

Aging Cell, Volume 25, Issue 2, February 2026.
Senescent hippocampal astrocytes lose TSP secretion, impairing excitatory synaptogenesis via the α2δ‐1 pathway. Restoring TSP‐1 rescues synaptic formation, revealing the contribution of astrocyte senescence to age‐related hippocampal synaptic decline.
Stefano Ercoli, Lucía Casares‐Crespo, Elena Juárez‐Escoto, Helena Mira   +3 more
wiley   +1 more source

Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary Aging

Aging Cell, Volume 25, Issue 2, February 2026.
Mouse models revealed age‐associated increased circumferential stiffness of the proximal pulmonary artery that was associated with reorientation of collagen and decreased function of the lung and right ventricle. Age‐related transcriptional changes were indicative of senescence, ECM turnover, TGFβ signaling, and altered intercellular signaling among ...
Ruben De Man, Zhongyu Cai, Pramath Doddaballapur, Nicole Guerrera, Alexandria Regan, Liqin Lin, Erica Schwarz, Aurelien Justet, Nebal S. Abu Hussein, Jack Di Palo, Cristina Cavinato, Micha Sam B. Raredon, Paul M. Heerdt, Inderjit Singh, Xiting Yan, Min‐Jong Kang, Danielle R. Bruns, Patty J. Lee, George Tellides, Jay D. Humphrey, Naftali Kaminski, Abhay B. Ramachandra, Edward P. Manning   +22 more
wiley   +1 more source

Nuclear mechanobiology rules immune cells' functions: from differentiation to cell trafficking and pathogen killing. [PDF]

Nucleus
Renkawitz J, Yesin A, Kroll J, Cabral AT, D'Annunzio S, Thiam HR.   +5 more
europepmc   +1 more source

LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation [PDF]

, 2013
Irina Solovei, Audrey S. Wang, Katharina Thanisch, Christine S. Schmidt, Stefan Krebs, Monika Zwerger, Tatiana V. Cohen, Didier Devys, Roland Foisner, Leo Peichl, Harald Herrmann, Helmut Blum, Dieter Engelkamp, Colin L. Stewart, Heinrich Leonhardt, Boris Joffe   +15 more
openalex   +1 more source

Effects of lamin A / C structure on 53BP1 foci kinetics

, 2021
Robert Lehn
openalex   +2 more sources

Denosumab Regulates Titanium Particles‐Induced Macrophages Inflammation and Osteolysis by Targeting the ST18/PARP1 Interaction

Orthopaedic Surgery, Volume 18, Issue 2, Page 322-334, February 2026.
The schematic diagram of the role of Denosumab and ST18/PARP1 axis in the prevention of prosthesis‐related AL. Denosumab regulates TiPs‐induced macrophage activation and osteolysis through the NF‐κB pathway and M1 polarization, with ST18 acting as a key mediator.
Zhipeng Chen, Fan Yang, Yifan Yu, Junxi Chen, Jichao Ye, Yue Ding   +5 more
wiley   +1 more source

Nucleoplasmic Lamin A/C controls replication fork restart upon stress by modulating local H3K9me3 and ADP-ribosylation levels. [PDF]

Nat Commun
Cherdyntseva V, Paulson J, González-Acosta D, Ubieto-Capella P, Rodrigues M, Aouami M, Adakli S, Gagné JP, Bakker C, Poirier GG, Taneja N, Lopes M.   +11 more
europepmc   +1 more source