Results 21 to 30 of about 173,782 (265)

Numerical simulation of hydraulic fracture propagation in laminated shale reservoirs

Petroleum Exploration and Development, 2020
The main area of the Jiaoshiba anticline of the Fuling shale gas field was taken as the research object, laboratory rock mechanical experiments and direct shear experiments were conducted to clarify the mechanical anisotropy characteristics and ...
Tong ZHOU, Haibo WANG, Fengxia LI, Yuanzhao LI, Yushi ZOU, Chi ZHANG   +5 more
doaj   +1 more source

Homeodomain proteins hierarchically specify neuronal diversity and synaptic connectivity

eLife
How our brain generates diverse neuron types that assemble into precise neural circuits remains unclear. Using Drosophila lamina neuron types (L1-L5), we show that the primary homeodomain transcription factor (HDTF) brain-specific homeobox (Bsh) is ...
Chundi Xu, Tyler B Ramos, Edward M Rogers, Michael B Reiser, Chris Q Doe   +4 more
doaj   +1 more source

Glomerular Basement Membrane: Lamina rara, Lamina densa

Kidney and Blood Pressure Research, 1981
Electron immunohistochemical and histochemical studies of glomerular and tubular basement membranes were undertaken to elucidate the relationship between lamina rara and lamina densa. Our results indicate that the lamina rara is not a fixation artifact and it has common antigenic determinants with lamina densa (type IV collagen antigens).
A, Martinez-Hernandez, C A, Marsh, J F, Horn, E, Munoz   +3 more
openaire   +2 more sources

Axis Screw Fixation – A Step-by-Step Review of the Surgical Techniques

Brazilian Neurosurgery, 2017
In this article, we present the techniques of axis screw fixation (laminar, pars, pedicle and transarticular screws), discussing the indications and contraindications of each one, as well as surgical tips and anatomical landmarks.
Andrei F. Joaquim, K. Daniel Riew
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The Long-Time Chronoamperometric Current at an Inlaid Microband (or Laminar) Electrode

Sensors, 2013
In this article, we derive an approximate asymptotic analytical expression for the long-time chronoamperometric current response at an inlaid microband (or laminar) electrode.
Christopher G. Bell
doaj   +1 more source

Morphological comparison of astrocytes in the lamina cribrosa and glial lamina

Investigative Ophthalmology & Visual Science
Abstract Purpose Although the mechanisms underlying glaucomatous neurodegeneration are not yet well understood, cellular and small animal models suggest that LC astrocytes undergo early morphologic and functional changes, indicating their role as early responders to glaucomatous ...
Susannah Waxman, Hannah Schilpp, Ashley Linton, Tatjana C. Jakobs, Ian A. Sigal   +4 more
openaire   +3 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Crosstalk between mitotic reassembly and repair of the nuclear envelope

Nucleus
In eukaryotic cells, the nuclear envelope (NE) is a membrane partition between the nucleus and the cytoplasm to compartmentalize nuclear contents. It plays an important role in facilitating nuclear functions including transcription, DNA replication and ...
Yohei Kono, Takeshi Shimi
doaj   +1 more source

Morphometric Analysis of Sub-axial Cervical Vertebrae and Its Surgical Implications [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background: The predilection of the cervical spine to a wide array of traumatic, degenerative and neoplastic diseases necessitates frequent surgical interventions.
Sandeep Saluja, Sachin Patil, Neelam Vasudeva   +2 more
doaj   +1 more source